The purpose of the academic paper is to study the most effective mechanisms for managing the health care system in the crisis caused by the spread of COVID-19. Methodology. The qualitative research methods (content analysis of strategic leadership) and a strategic approach to the formation of a mechanism for managing the health care system within the conditions of the coronavirus pandemic have been used in the academic paper. The study is based on the concept of strategic management within the conditions of crisis based on data from the World Health Organization, which contains information on the response of health care systems to the coronavirus pandemic, management policy in terms of basic governance criteria. In order to analyze and assess the differences, advantages and disadvantages of governance, four countries with different levels of social-economic development and geographical location have been selected, namely: Germany, Georgia, Italy, and Ukraine. The results show the dependence of the effectiveness of health care management mechanisms within the conditions of the crisis on the level of centralization, social-economic development of the country. Advanced countries rely on their own governance apparatus with a greater level of regional independence in decision-making, in particular on legal regulation. Countries with economies in transition are dependent on the governance and coordination recommendations of international organizations due to the weakness of legal regulation, institutions, research organizations and the level of development of civil society institutions. The level of centralization of management mechanisms determines the level of effectiveness of legal regulation and institutional support. In terms of advanced countries, this causes some shortcomings in the management of the health care system, however in countries with economies in transition it leads to inefficient management due to excessive centralization. The practical significance lies in the possibility of transition economies to use the experience of advanced countries in the management of the health care system. How to Cite this Article Pubmed Style Oleg C, Mariana I, Viktoriia Z, Iryna B, Yuliya V, Nataliia T. for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). SRP. 2020; 11(10): 258-264. doi:10.31838/srp.2020.10.42 Web Style Oleg C, Mariana I, Viktoriia Z, Iryna B, Yuliya V, Nataliia T. for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). http://www.sysrevpharm.org/?mno=16823 [Access: March 30, 2021]. doi:10.31838/srp.2020.10.42 AMA (American Medical Association) Style Oleg C, Mariana I, Viktoriia Z, Iryna B, Yuliya V, Nataliia T. for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). SRP. 2020; 11(10): 258-264. doi:10.31838/srp.2020.10.42 Vancouver/ICMJE Style Oleg C, Mariana I, Viktoriia Z, Iryna B, Yuliya V, Nataliia T. for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). SRP. (2020), [cited March 30, 2021]; 11(10): 258-264. doi:10.31838/srp.2020.10.42 Harvard Style Oleg, C., Mariana, . I., Viktoriia, . Z., Iryna, . B., Yuliya, . V. & Nataliia, . T. (2020) for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). SRP, 11 (10), 258-264. doi:10.31838/srp.2020.10.42 Turabian Style Oleg, Chornyi, Iskiv Mariana, Zagurska-Antoniuk Viktoriia, Borysiuk Iryna, Volkova Yuliya, and Terentieva Nataliia. 2020. for Managing the Health Care System within the Conditions of the Coronavirus Pandemic Reviews in Pharmacy, 11 (10), 258-264. doi:10.31838/srp.2020.10.42 Chicago Style Oleg, Chornyi, Iskiv Mariana, Zagurska-Antoniuk Viktoriia, Borysiuk Iryna, Volkova Yuliya, and Terentieva Nataliia. Mechanisms for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). Systematic Reviews in Pharmacy 11 (2020), 258-264. doi:10.31838/srp.2020.10.42 MLA (The Modern Language Association) Style Oleg, Chornyi, Iskiv Mariana, Zagurska-Antoniuk Viktoriia, Borysiuk Iryna, Volkova Yuliya, and Terentieva Nataliia. Mechanisms for Managing the Health Care System within the Conditions of the Coronavirus Pandemic (COVID-19). Systematic Reviews in Pharmacy 11.10 (2020), 258-264. Print. doi:10.31838/srp.2020.10.42 APA (American Psychological Association) Style Oleg, C., Mariana, . I., Viktoriia, . Z., Iryna, . B., Yuliya, . V. & Nataliia, . T. (2020) for Managing the Health Care System within the Conditions of the Coronavirus Pandemic Reviews in Pharmacy, 11 (10), 258-264. doi:10.31838/srp.2020.10.42