Objective: Determine the impulse of the components of the spin-offs that allow the creation of economic value in the area of economic-business sciences of the National University of the Altiplano Puno. Theoretical Framework: University spin-offs arise from the knowledge, technology or research results generated within a university, from its components: level of maturity of the technology, level of entrepreneurial intention and the maturity of the ecosystem. Method: The methodology is a descriptive-correlational design, quantitative approach, non-experimental. The population was made up of students and teachers from the area of economic and business sciences of the National University of the Altiplano Puno, with a sample of 453. The technique for data collection was a questionnaire. Results and Discussion: The results obtained were a correlation coefficient r = 0.830 in the level of technology maturity (fair), r = 0.876 in entrepreneurial intention (good) and r = 0.752 in the maturity of the ecosystem (fair). The component that facilitates the creation of technology-based companies or university spin-offs is the level of entrepreneurial intention, with a high level. Suggesting that to strengthen a spin-off, it is crucial to have well-developed technology, motivated entrepreneurs and a favorable ecosystem. Research Implications: the model provides a strategic framework for students, teachers and university authorities to develop the components of spin-offs to increase economic value. Originality/Value: This study contributes to the literature on spin-offs. The relevance and value of this research is evident in the results.