Leiomyoma Of Scrotum Research Articles

Inguinal hernia coexisting with spermatic cord leiomyoma

Leiomyomas primarily occur in the uterus, small bowel, and esophagus, with occasional instances found in the genitourinary system-bladder, epididymis, prostate, testis, and penis. Among these, scrotal leiomyomas, belonging to genital leiomyomas, present as solitary growths within scrotal structures, displaying gradual growth. Specifically, spermatic cord leiomyoma is exceptionally rare, with limited cases since the 1950s. A 63-year-old male exhibited persistent left groin pain and swelling, initially suggesting a hernia. Examination revealed an inguinal hernia and a palpable, mobile 3 cm solid mass. Ultrasonography identified a well-defined solid hypoechoic lesion. Magnetic resonance imaging (MRI) displayed a 37x24 mm ovoid lesion, hinting at its origin from the spermatic cord. Surgical intervention involved hernia repair and mass excision, confirming leiomyoma via histopathology. Spermatic cord leiomyomas, rare and hernia-mimicking, highlight the crucial role of MRI in accurate preoperative diagnosis, emphasizing the need to consider leiomyoma in inguinal mass differentials.

Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report

Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th century, are characterized by benign pathology from the subcutaneous dartos muscle. We present two cases of middle-aged males with scrotal leiomyomas, detailing clinical presentations, histopathological findings, and immunohistochemistry results. The first involved a 48-year-old with a painless scrotal lump, excised to reveal well-circumscribed smooth muscle bundles. Immunohistochemistry confirmed vimentin, desmin, and smooth muscle actin (SMA) positivity, consistent with scrotal leiomyoma. The second case featured a 25-year-old with a painless scrotal swelling, histologically matching the features of scrotal leiomyoma. Accurate diagnosis is crucial for guiding appropriate management strategies. Clinicians often employ a combination of clinical evaluation, imaging studies, and histopathological examination to confirm the presence of scrotal leiomyomas. Ultrasound remains a valuable tool for assessing the size, location, and vascularity of the tumor, aiding in the formulation of a differential diagnosis. Definitive diagnosis, however, relies on histological examination, which typically reveals spindle-shaped smooth muscle cells arranged in interlacing bundles.

Scrotal Leiomyoma: Report of a Rare Case.

Leiomyomas are benign mesenchymal tumours of smooth muscle origin. They can arise anywhere in the body where smooth muscle is present. Superficial leiomyomas are categorised into three types based on their site of origin: piloleiomyoma arising from arrector pili, scrotal arising from dartos, and angioleiomyoma arising from smooth muscles of blood vessels. Scrotal leiomyomas are rare tumour, and very few cases are reported in literature so far. We report a case of scrotal leiomyoma clinically diagnosed as epidermal cyst.

Scrotal leiomyoma: a rare cause of scrotal swelling

BackgroundLeiomyomas are benign smooth muscle tumours predominantly found in the uterus. Rarely, they may be located in the ovaries, scrotum, bladder, lungs, vascular structures and spermatic cord.Case presentationWe managed a 39-year-old man who presented with a year history of progressive right-sided hemiscrotal swelling. The right scrotal mass was excised, and histology showed scrotal leiomyoma.ConclusionScrotal leiomyoma is very rare and challenging to diagnose pre-operatively as a cause of scrotal swelling, but it is amenable to surgical excision.

Giant scrotal leiomyoma: Report of a rare case and review of literature

Background: Leiomyoma is a benign tumour of smooth muscles that can arise almost anywhere in the body; however, scrotal Leiomyomais a rare entity. It may originate from dartos muscle, epididymis or spermatic cord. The neoplasm has an insidious course, and clinically it may mimic many intrascrotal tumours, including testicular cancers, resulting in diagnostic challenges.Case report: A 20-year-old student evaluated for a painless right testicular swelling of 1year duration, suspicious of right testicular cancer. He had right radical orchidectomy done, but the histology result of the specimen came out to be paratesticular leiomyoma compressing and causing total atrophy of the right testis, the specimen measured 10x7x6cm and weighed 600g. Post-operative condition and follow up were satisfactory.Conclusion: Scrotal leiomyoma is rare and when it presents as huge mass can cause challenges in diagnosis and treatment, particularly in developing countries. Close follow-up and molecular testing are important in detecting renal cell carcinoma in case of hereditary autosomal dominant disorders that may coexist with this tumour. Keywords: Paratestisticular, Giant, Dartos muscle, Leiomyoma.

Paratesticular Tumors: A Report of Two Rare Cases

Paratesticular tumors are rare comprising 7-10% of total intrascrotal tumors of which 70% are benign and 30% are malignant. Leiomyomas and undifferentiated pleomorphic sarcomas are two such rare paratesticular tumors which should be accurately diagnosed for purpose of treatment and prognosis. We report here two cases. In first case, a 65-year-old man presented with paratesticular mass of 12 years duration. Histology showed features of benign spindle cell tumor. On immunohistochemistry the tumor cells were positive for vimentin, desmin, h-caldesmon and SMA. Based on these findings a diagnosis of leiomyoma of scrotum was made. In second case, a 66-year-old male presented with left paratesticular mass of eight months duration. Histology showed features of high-grade sarcoma. On immunohistochemistry tumor cells were focally positive for SMA and negative for h-caldesmon, desmin, calretinin and ALK-1. A final diagnosis of undifferentiated pleomorphic sarcoma of paratesticular region, grade 3/3 was made.

A rare case of paratesticular leiomyoma in a child.

Leiomyomas are benign, slow-growing, smooth muscle tumors, which can occur at many locations in the body. The male genitourinary tract is seldom affected and scrotal leiomyomas are extremely rare. Most of the scrotal leiomyomas are localized in the testis, epididymis, spermatic cord, subcutaneous tissue, tunica albuginea, and scrotal skin and only a few of them are reported in the origin of isolated tissue without paratesticular structures in the paratesticular region. We are presenting a case of solitary paratesticular leiomyoma in a child, which is very rare in terms of lesion location and patient age, and describing the imaging features of this lesion.

Leiomyoma of scrotum: A case report of a common benign tumor at a rare site

Introduction: Leiomyoma is a benign tumor of smooth muscles that can arise almost anywhere in the body, where smooth muscle is present. Leiomyoma of the scrotum is a rare entity described as a benign pathology arising from subcutaneous tissue or dartos muscle. Case history: Here, we report a case of solitary scrotal leiomyoma presenting with lump on medial aspect of left side of scrotum since 6 moths. This case has been reported for its rarity as presented with very short history till the date in literature. Conclusion: Leiomyoma of the scrotum is a rare benign mesenchymal neoplasm. This case points to importance of the clinicopathological characteristics of the scrotal smooth muscle tumors in elderly patient, with skin ulceration & in shorter duration to prevent erroneous diagnosis & treatment.

Scrotal leiomyoma

Scrotal leiomyomata are rare benign tumours of the dartos muscle or subcutaneous tissues of the scrotum. We present a case of a 33-year-old male with a left hemiscrotal mass which was initially thought to be a sebaceous cyst, and later, a paratesticular tumour. Histology of the excised mass revealed a scrotal leiomyoma, an uncommon lesion.

Leiomyoma of scrotum

Leiomyoma is a benign tumor of smooth muscle. Leiomyoma originating from the scrotum is rare. We report here a case of 50-year-old male who presented with a lump in the left side of scrotum. Clinically, it was diagnosed as sebaceous cyst and was excised. The histopathology showed findings consistent with leiomyoma. There was no cytological atypia. The final diagnosis of solitary scrotal leiomyoma was given.

Rare Leiomyoma of the Tunica Dartos: A Case Report with Clinical Relevance for Malignant Transformation and HLRCC.

Background. Genital leiomyomas fall under the broader category of cutaneous leiomyomas, which are rare smooth muscle neoplasms accounting for 5% of all leiomyomas. Genital leiomyomas arising from the dartos muscle are exceedingly rare with fewer than 30 cases reported in the literature. They are typically benign and adequately treated with simple surgical excision; however, previously reported cases of malignant transformation and a possible link to the hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome warrant closer follow-up. Case Presentation. We report a case of a 47-year-old male refugee from Rwanda found to have a mobile, pea-sized, mildly painful scrotal lesion near the left penoscrotal junction and 1.5 cm indeterminate vascular mass in the right kidney. Surgical excision of the scrotal nodule was performed and the diagnosis of a dartoic leiomyoma was rendered. The presence of moderate nuclear atypia, rare mitotic activity, and close surgical margins prompted a wide reexcision. We report the surgical approach, pathologic findings, and clinical follow-up related to this scrotal lesion. Conclusion. Scrotal leiomyomas demonstrate a high rate of recurrence and pose a risk for malignant transformation. They may also indicate an underlying autosomal dominant syndrome associated with increased risk for development of an aggressive form of renal cell carcinoma. When discovered, management should include surgical excision, screening for syndromic features, and routine follow-up.

Monströses scrotales Leiomyom; Fallbericht und Überblick über die Literatur

The scrotal leiomyoma is a rare benign tumour, deriving from the smooth muscle. This tumour entity constitutes a differential diagnosis to malignant testicular tumours. Up to now, only 8 cases have been reported in the literature. We report on a 63-year-old European patient, presenting in our clinic for further treatment with a now monstrous mass of the left testis (about 8 kg) that has been growing for about 30 years, After partial scrotalectomy and orchiectomy pathological analysis confirmed a left-sided leiomyoma of the testicular/paratestical tissue. This case shows that even rare tumours should be included in the differential diagnosis of a testicular tumour.

Atypical leiomyoma of scrotum

Atypical leiomyoma of scrotum

Leiomyoma cutis: A clinicopathological series of 37 cases

Background:Cutaneous leiomyomas are benign smooth muscle tumors that comprise three distinct types such as piloleimyoma, angioleiomyoma, and genital leiomyoma.Aim:The objective of this study was to report a series of cases seen in last 8 years in a tertiary care hospital in north India and to discuss their clinicopathologic findings.Material and Methods:Paraffin-embedded blocks of cases reported as cutaneous leiomyoma from 1999 to 2007 were retrieved from the Institute of Pathology, New Delhi, and their clinical parameters were noted. Their histopathological features were reviewed on hematoxylin-eosin stained slides. Immunohistochemistry was performed where necessary.Results:Twenty-seven cases of piloleiomyoma, three cases of angioleiomyoma, five breast leiomyomas, and two scrotal leiomyomas were seen in patients ranging from 21 to 65 years of age, with an average of 38.2 years at presentation. There was a male predominance with 26 males and 11 females (M:F = 2.2:1). Solitary lesions (n = 21) were more common than multiple ( n = 16). The trunk and upper limbs were involved most commonly, comprising 23 of 37 (62.2%) cases. This was followed by lower limb, face, breast, and scrotum.Conclusion:Cutaneous leiomyomas are rare lesions and form an important clinical differential diagnosis of painful papulonodules. These must be biopsied in order to differentiate them from other spindle cell lesions.

Scrotal Leiomyoma

Scrotal Leiomyoma

Symplastic scrotal leiomyoma: a case report

IntroductionScrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case.Case presentationWe report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up.ConclusionHistological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up.

Leiomyoma of scrotum

Leiomyoma is a benign tumor of smooth muscles. Leiomyoma originating from the scrotum is a rare entity. We report here a case of 50-year-old male who presented with a 4-cm lump in the left side of scrotum. Clinically, it was provisionally diagnosed as sebaceous cyst and was excised. The histopathology showed findings consistent with leiomyoma. There was no cytological atypia or mitosis. The final diagnosis of solitary leiomyoma of scrotum was given. The patient was followed up regularly and is doing fine for last 4 months.

Male genital leiomyomas showing androgen receptor expression

Genital leiomyoma in men include those superficial leiomyomas arising in the scrotum and the areola. They are unusual neoplasms: few cases have been reported in the literature and they usually escape clinical diagnosis. Three cases of male genital leiomyomas are reported: two in the scrotum and one in the areola. They were all conservatively excised and the behaviour was completely benign in all cases. Histopathological examination showed the typical findings of superficial leiomyomas, with some minor differences between cases arising in the scrotum and those from the areola. Immunohistochemical findings not only confirmed the smooth muscle nature of all cases but also showed unequivocal immunostaining for androgen receptors in the leiomyomas from the scrotum. Immunostaining for androgen receptors in scrotal leiomyomas is, as far as we are aware, a previously unknown characteristic of male genital leiomyomas. This finding supports the role of steroid hormones in the growth of genital leiomyomas, similar to leiomyomas found in other locations.

Leiomioma de escroto: aportación de un caso

Scrotal leiomyoma is a benign rare tumour, asymptomatic, which origin is the dartos muscle and the election treatment is surgical. We report a new case in a 68-year-old patient with a 10 years history of a scrotal tumour and anatomopathological diagnostic post surgery was leiomyoma.

Leiomioma escrotal pediculado

Abstract—Leiomyoma of the scrotum is a very uncommon benign mesenchymal tumour, which is found mainly in adults. We describe the case of a 67-year-old male patient with a pedunculated scrotal leiomyoma of ten-year duration.