The existence of cybersecurity regulations in Honduras aimed at safeguarding clinical data remains uncertain, leaving the populace’s health information vulnerable due to the absence of robust legal frameworks. This study sheds light on the current landscape concerning health information protection in the country, underscoring its profound impact on securing medical information systems and the realm of Internet of Things (IoT). It underscores the potential of blockchain technology to provide an innovative solution to address security challenges in this domain. Employing a systematic approach, the research delineates a timeline to elucidate the evolution of legal measures against cybercrime in Honduras, consolidating pertinent governmental documents associated with cybersecurity and the protection of medical data. Furthermore, it underscores the healthcare sector’s susceptibility to cyber threats and the primary privacy apprehensions pertaining to IoT applications in medicine. The study concludes that Honduras lacks a dedicated data protection statute, posing a significant impediment to cybersecurity regulatory efforts. This legal void impedes the effective implementation of measures to safeguard clinical information and shield it from potential cyber risks amidst the proliferation of IoT initiatives and healthcare-related ventures. Nonetheless, this circumstance may present an opportunity for the adoption of technologies such as blockchain. By enabling the establishment of tailored regulatory frameworks, blockchain can adapt to its unique attributes, thereby facilitating its integration in fortifying clinical data protection and enhancing overall cybersecurity protocols.