LetXi,Yii=1,2be Banach spaces. The operator matrix of the formMC=AC0Bacting betweenX1⊕X2andY1⊕Y2is investigated. By using row and column operators, equivalent conditions are obtained forMCto be left Weyl, right Weyl, and Weyl for someC∈ℬX2,Y1, respectively. Based on these results, some sufficient conditions are also presented. As applications, some discussions on Hamiltonian operators are given in the context of Hilbert spaces.