Left-turn movements at signalized intersections pose significant safety risks for the drivers and efficiency concerns for the traffic operations in urban networks. Restricting left-turn movements at selected locations has been shown to be effective at improving operational efficiency and mitigating safety concerns. However, determining optimal locations to restrict left-turns is a complex combinatorial optimization problem that is compounded by the lack of analytical forms for the objective function and constraints, as well as potential interdependencies between the decision variables. Following the common solution paradigm for this type of optimization problems, this paper presents a novel Bayesian approach that utilizes dictionary-based embeddings and is tailored for high-dimensional combinatorial (or even mixed) spaces. Simulation studies conducted using the Aimsun software under perfect or imperfect grid networks demonstrate that the presented method can consistently find promising left-turn restriction configurations that outperform the all-or-nothing strategies (to restrict all or none left-turn movements at all intersections), as well as the population based incremental learning algorithm. In addition, the presented method often does so with less simulation cost, thus showcasing its potential for efficient solution of more general traffic optimization problems.