The emergence of the COVID-19 pandemic marked an unprecedented disruption in global education systems, affecting a vast population of approximately 1.6 billion learners across over 200 countries. Specifically, within Malaysia, where private universities hold a significant role in shaping the educational sphere, the pandemic brought about notable shifts in higher education. This research focuses on the post-pandemic impact on a private university situated in the Malaysian capital, focusing on transformations in teaching and learning approaches, student engagement, and technological integration in chemistry education. Through an in-depth analysis of diverse data sources from students and literatire review, this study aims to shed light on the challenges faced by the teaching and learning process in chemistry and the strategies employed to mitigate the adverse effects. In addition, the study also discusses the potential long-term transformations in higher education that may persist beyond the pandemic and offers recommendations to ensure the resilience and adaptability of private universities in Malaysia. Understanding the post-pandemic impact on private universities is crucial for formulating effective policies and strategies to enhance the quality and accessibility of higher education in the evolving educational landscape.