An air-filled substrate-integrated waveguide (AF-SIW) circularly polarized (CP) 1 × 8 mm wave antenna array is presented for fifth-generation (5G) applications. The presented slot antenna array consists of three layers of PCB and one layer of aluminum, which serve as the AF-SIW feeding network and the metal cavity radiation element, respectively. The CP characteristic is achieved by the use of an S-shaped aluminum radiation cavity on the top of the AF-SIW feeding network. The air-filled substrate-integrated waveguide technique is unitized to achieve high radiation efficiency. A wide input impedance bandwidth of 18.4% is obtained for the proposed antenna scheme, ranging from 34.5 GHz to 41.5 GHz, with a peak gain of 18 dBic. As for CP characteristic, the proposed antenna possesses a wide 3 dB axial ratio (AR) bandwidth, which is 16.4% (36.5 GHz to 43 GHz). The antenna scheme is fabricated and measured to verify the potential application as well as the promising performance. The measured results of the 1 × 8 antenna array shows that the wide AR as well as the input impedance are simultaneously achieved, which coincide well with the simulated results. Also, the measured results indicate that the proposed antenna scheme might be a good candidate for future mobile applications.