Abstract: Introduction: Healthcare decision-making is a critical yet understudied aspect of medical education. It holds significant importance among healthcare professionals and influences their overall behavior. We adapted and validated the Decision-Making Questionnaire, which measures factors affecting decision-making among obstetricians and gynecologists. Methods: We used a cross-sectional survey design to establish the construct validity of the DMQ. We established content validity using the Lawshe content validity ratio and conducted a survey to establish the construct validity. Results: Exploratory factor analysis ( n = 150) revealed three factors, task-related, context-related, and individual-related, having eigenvalues greater than 1 and adequate alpha reliability. Confirmatory factor analysis ( n = 197) found adequate model fit indices. We assessed the reliability coefficient of the Decision-Making Questionnaire using Cronbach’s alpha and McDonald’s Omega coefficient, which showed an acceptable range (0.86–0.90). Hence, the scale appears to be psychometrically sound and a practical measure for obstetricians and gynecologists. Discussion: The Decision-Making Questionnaire demonstrated convergent validity by positively correlating with the Team Decision-Making Questionnaire and divergent validity by showing correlations with the measure of professional quality of life. The scale is useful for practitioners and researchers to measure factors affecting decision-making in naturalistic settings.