The desublimation crystallization of trace impurity gas at the temperature of liquid hydrogen and liquid oxygen is a common problem in cryogenic engineering, which usually leads to the failure of cryogenic liquid transportation. Liquid hydrogen and liquid oxygen are important aerospace propellants. In the pressurization process of cryogenic liquid propellant, a small amount of water vapor and other gases in the pressurized gas would appear desublimation and crystallization at low temperature. Inevitably, as the tail gas of hydrogen combustion, water vapor sometimes diffused into cryogenic liquid. This kind of desublimation crystallization was accompanied by heat and mass transfer, accompanied by gas-solid phase transition, moving boundary, random and extremely complicated crystallization growth process. It was of great engineering practical significance to study the heat and mass transfer mechanism and law of this complex desublimation phase change phenomenon for the progress and development of engineering technologies such as refrigeration, cryogenics and aerospace. In this paper, based on the homogeneous desublimation theory, the pressurization system of liquid oxygen tank with oxygen containing trace water vapor was taken as the research object, and the basic data of ice crystal formation and growth during pressurization, such as crystallization quantity, crystallization speed and size distribution, were calculated theoretically. It provided a theoretical basis for the experimental study of the real dynamic characteristics and laws of desublimation crystallization in the propulsion system. The research methods and conclusions in this paper also had some guiding significance for the use of liquid hydrogen in the storage, transportation and use of the hydrogen energy.