Pavement performance in clay soil roads can be enhanced with the help of the geogrid concept by increasing lateral confinement, bearing capacity, and overall rigidity of the pavement. Also, geogrid is useful in minimizing vertical and lateral pavement deformations. In this study, 65 tests are performed without and with two types of geogrid, and the aim behind it is to investigate the effect of the moisture content and degree of compaction of clay soil on the interface shear strength. The number of materials used to conduct this study, included subbase granular (type B), clay subgrade soil, the Biaxial and SS2 geogrid which is used as a reinforcing material. Testing the direct shear is conducted by a large-scale direct shear manufactured device contains an upper box with side lengths of (20×20×10) cm, and a lower box with side lengths of (20×25×10) cm. Results show that for all tests the normal applied stresses are 25, 50, 75 and 100 kPa, the shear stress displacement curves for all cases follow similar trends and they are affected by normal stress, density and water content of subgrade soil and type of geogrid. Also, it is obvious that the shear stress increases by increasing the normal applied stress and degree of compaction of clay subgrade soil reaching its maximum value at 95% degree of compaction while it decreases by increasing the water content of subgrade soil. The maximum value of shear strength is observed when water content is equal to 8% (dry side) and finally, the Biaxial geogrid BX1100 (G1) is more efficient in reinforcing clay-subbase interface as compared with SS2 geogrid (G2).