In order to study the influence of the space linkage system on the stability of the straddle-type monorail vehicle with single-axle bogies, the sensitivity analysis of the space linkage system is identified based on the Pearson coefficient method to determine the importance of each component of the single-axle bogies. The dynamics model of straddle-type monorail vehicle with single-axle bogies is established by the multi-rigid body dynamics. The Pearson analysis method is used to identify the key parameters of the space linkage system. Based on that, dynamic response optimization model of space bar system is developed to carry out a multi-objective suspension design optimization process. The results show that the maximum sensitivity parameter for the RMS value of yaw acceleration and pitch angle acceleration is the length of the longitudinal tow bar; there is a correlation of approximately 0.088 between the stiffness K and the damping coefficient C of the hydraulic shock absorber. After optimization the root mean square of lateral acceleration of the optimized single-axle bogie vehicle is reduced by 6.0%.