Laser hair reduction is one of the most common laser procedures in dermatology. Laser systems available are Ruby at 694nm, Alexandrite (755nm), Diode (810nm), and Nd:YAG (1064nm). Recently, devices presenting a combination of wavelengths have shown to produce high effective hair reduction with no related risks. This study was conducted with the Soprano Ice Platinum (Alma Lasers, GMBH, Germany) that emits a combination of three wavelengths at 755, 810, and 1064nm in a single pulse. To establish the efficacy and safety of novel triple wavelength laser hair reduction technology in skin types IV to V. This was an investigator initiated, single-center, prospective clinical study conducted between December 2017 and June 2019 with a total of 25 patients (23 female and two male) above 18years with skin types IV and V, areas included are face, beard, neck, chest, and others. Hair reduction was assessed using the physician GAIS (global esthetic improvement scale) score: no results 0% reduction, poor 0%-25% reduction, average 25%-50%, good 50%-75%, and excellent 75%-100%. All 25 patients (mean age 28years, range 18-52 y/o) completed all six sessions of the study. Objective clinical assessment of hair reduction using the physician GAIS score in 90 anatomical sites scores an excellent reduction in 95.5% areas and good reduction in 80% areas. This current study shows that a synergistic combination of three diode laser wavelengths used for hair removal (755, 810, 1064nm) is effective and safe to use in subjects skin types IV and V for facial and body hair.