Large X-ray Absorption Research Articles

Eu2+ doped cesium alkaline earth chloride nanocrystals in glass for X-ray imaging

High-performance and low-cost metal halide perovskite scintillator materials have important applications in X-ray detection and imaging. However, large-sized perovskite scintillator panel with high transmittance, low toxicity and long-term stability is still lacking. Herein, Eu2+ doped cesium alkaline earth chloride nanocrystals (Eu2+: CsCaCl3, Eu2+: CsSrCl3, and Eu2+: Cs2BaCl4 NCs) embedded in glasses through conventional melt-quenching and subsequent heat-treatment were developed. These NCs doped glasses exhibited highly efficient and narrowband photoluminescence in blue region. Benefitting from the large X-ray absorption coefficient and high photoluminescence quantum yied, these Eu2+: CsCaCl3 NCs doped glass scintillator shows light yield of ∼9300 photons/MeV, detection limit of ∼213.8 μGy/s, and spatial resolution of 30.0 lp/mm. These results demonstrated that glasses containing Eu2+ doped cesium alkaline earth chloride nanocrystals are promising for X-ray detection and imaging.

Reconstruction of dendritic growth by fast tomography and phase field filtering

Three dimensional models of dendritic structures during solidification are valuable for building physical models, validating simulated results, estimating some properties such as permeability in the mushy, simulating semisolid deformation and so on. Thus, it is of interest to observe microstructure evolution in situ. Time-resolved tomography combined with X-ray diffraction has allowed us to observe the evolution of dendritic structures and to measure crystallographic orientation in situ. Reconstruction still proves to be difficult for some alloy systems because of the tradeoff between time and spatial resolution. This paper demonstrates the reconstruction of dendritic structures for three different alloy systems (Al-10mass%Cu alloy with a diameter of 4 mm, CrMnFeCoNi alloy with 1 mm, and Zn-4mass%Al alloy with 0.7 mm). The observations were performed in a synchrotron radiation facility SPring-8. A filter using a phase field model was introduced to reconstruct the three-dimensional images. Parameters used in the filtering were consistently determined based on the raw reconstruction images. Evaluation of solid-liquid interface area and curvature was significantly improved by the filter. For the Al-Cu alloy, a three-dimensional model containing approximately 300 million voxels was obtained. For the CrMnFeCoNi alloys, the preferred growth direction <100> was confirmed by tomography and X-ray diffraction. For the Zn-Al alloy, the observed 14 growth directions were not simply defined by the crystallographic orientations, although the directions were consistent with the hexagonal symmetry. This study verifies that time resolved tomography, X-ray diffraction and the filter using a phase field model provide three dimensional models for light metal alloys with rather large diameters and 3d transition-metal alloys with rather large X-ray absorption coefficients. The models are expected to be used for further studies.

Single Crystal CdSe X-ray Detectors with Ultra-High Sensitivity and Low Detection Limit.

CdSe single crystals (SCs), with a relatively high atomic number, large X-ray absorption coefficients, and high carrier mobility, are expected to provide high-performance detection for X-ray. However, the difficulty of growing high-quality CdSe SC has severely limited its application in X-ray detection. In this work, we develop an unconstrained physical gas phase method and in situ annealing process to grow high-quality CdSe SCs under unconstrained conditions. Using this method, CdSe SCs exhibit natural exposure planes, ultrahigh resistivity of 5.43 × 1012 to 1.29 × 1013 Ω cm and high μτ product of 1.3 × 10-2 to 1.5 × 10-2 cm2 V-1. It is also observed that CdSe SC X-ray detectors exhibit a record sensitivity of 2.08 × 105 μC Gyair-1 cm-2 and a low detection limit of 85 nGyair s-1, which are both desired in medical diagnostics. Moreover, those devices with different crystal directions provide anisotropic X-ray detection performance. Our findings pave a new avenue to exploit high-performance CdSe SC X-ray detectors.

Properties of AGN Multiband Optical Variability in the HSC SSP Transient Survey

Abstract We study variability of active galactic nuclei (AGNs) by using the deep optical multiband photometry data obtained from the Hyper Suprime-Cam Subaru Strategic Program (HSC SSP) survey in the COSMOS field. The images analyzed here were taken with 8, 10, 13, and 15 epochs over three years in the g, r, i, and z bands, respectively. We identified 491 robust variable AGN candidates, down to i = 25 mag and with redshift up to 4.26. Ninety percent of the variability-selected AGNs are individually identified with the X-ray sources detected in the Chandra COSMOS Legacy survey. We investigate their properties in variability by using structure function analysis and find that the structure function for low-luminosity AGNs (L bol ≲ 1045 erg s−1) shows a positive correlation with luminosity, which is the opposite trend for the luminous quasars. This trend is likely to be caused by a larger contribution of the host galaxy light for lower-luminosity AGNs. Using the model templates of galaxy spectra, we evaluate the amount of host galaxy contribution to the structure function analysis and find that dominance of the young stellar population is needed to explain the observed luminosity dependence. This suggests that low-luminosity AGNs at 0.8 ≲ z ≲ 1.8 are predominantly hosted in star-forming galaxies. The X-ray stacking analysis reveals the significant emission from the individually X-ray undetected AGNs in our variability-selected sample. The stacked samples show very large hardness ratios in their stacked X-ray spectrum, which suggests that these optically variable sources have large soft X-ray absorption by dust-free gas.

Inorganic, Organic, and Perovskite Halides with Nanotechnology for High–Light Yield X- and γ-ray Scintillators

Trends in scintillators that are used in many applications, such as medical imaging, security, oil-logging, high energy physics and non-destructive inspections are reviewed. First, we address traditional inorganic and organic scintillators with respect of limitation in the scintillation light yields and lifetimes. The combination of high–light yield and fast response can be found in Ce 3 + , Pr 3 + and Nd 3 + lanthanide-doped scintillators while the maximum light yield conversion of 100,000 photons/MeV can be found in Eu 3 + doped SrI 2 . However, the fabrication of those lanthanide-doped scintillators is inefficient and expensive as it requires high-temperature furnaces. A self-grown single crystal using solution processes is already introduced in perovskite photovoltaic technology and it can be the key for low-cost scintillators. A novel class of materials in scintillation includes lead halide perovskites. These materials were explored decades ago due to the large X-ray absorption cross section. However, lately lead halide perovskites have become a focus of interest due to recently reported very high photoluminescence quantum yield and light yield conversion at low temperatures. In principle, 150,000–300,000 photons/MeV light yields can be proportional to the small energy bandgap of these materials, which is below 2 eV. Finally, we discuss the extraction efficiency improvements through the fabrication of the nanostructure in scintillators, which can be implemented in perovskite materials. The recent technology involving quantum dots and nanocrystals may also improve light conversion in perovskite scintillators.

Energy response characterization of InGaP X-ray detectors

Two custom-made In0.5Ga0.5P p+-i-n+ circular mesa spectroscopic X-ray photodiodes with different diameters (200 μm and 400 μm) and a 5 μm i layer have been characterized for their response to X-ray photons within the energy range 4.95 keV to 21.17 keV. The photodiodes, operating uncooled at 30 °C, were coupled, in turn, to the same custom-made charge-sensitive preamplifier. X-ray fluorescence spectra of high-purity calibration foils excited by a Mo target X-ray tube were accumulated. The energy resolution (Full Width at Half Maximum) increased from 0.79 ± 0.02 keV at 4.95 keV to 0.83 ± 0.02 keV at 21.17 keV, and from 1.12 ± 0.02 keV at 4.95 keV to 1.15 ± 0.02 keV at 21.17 keV, when using the 200 μm and 400 μm diameter devices, respectively. Energy resolution broadening with increasing energy was attributed to increasing Fano noise (negligible incomplete charge collection noise was suggested); for the first time, the Fano factor for In0.5Ga0.5P was experimentally determined to be 0.13, suggesting a Fano limited energy resolution of 145 eV at 5.9 keV. The charge output of each system had a linear relationship with photon energy, across the investigated energy range. The count rate of both spectroscopic systems increased linearly with varying X-ray tube current up to ∼105 photons s−1 cm−2 incident photon fluences. The development of In0.5Ga0.5P based spectrometers is particularly important for hard X/γ-ray astronomy, due to the material’s large linear X-ray and γ-ray absorption coefficients and the ability to operate uncooled at high temperatures.

Peculiar near-band-edge emission of polarization-dependent XEOL from a non-polar a-plane ZnO wafer.

Polarization-dependent hard X-ray excited optical luminescence (XEOL) was used to study not only the optical properties but also the crystallographic orientations of a non-polar a-plane ZnO wafer. In addition to a positive-edge jump and extra oscillations in the near-band-edge (NBE) XEOL yield, we observed a blue shift of the NBE emission peak that follows the polarization-dependent X-ray absorption near-edge structure (XANES) as the X-ray energy is tuned across the Zn K-edge. This NBE blue shift is caused by the larger X-ray absorption, generating higher free carriers to reduce the exciton-LO phonon coupling, which causes a decrease in the exciton activation energy. The extra oscillations in XANES and XEOL as the polarization is set parallel to the c-axis is attributed to simultaneous excitations of the Zn 4p - O 2pπ -bond along the c-axis and the bilayer σ-bond, whereas only the σ-bond is excited when the polarization is perpendicular to the c-axis. The polarization-dependent XEOL spectra can be used to determine the crystallographic orientations.

Short-wave near-infrared emissive GdPO4:Nd3+ theranostic probe for in vivo bioimaging beyond 1300 nm.

The optical probes working in the second near-infrared (NIR-II) window have attracted increasing research interest for their advantages of high tissue penetration depth, low autofluorescence, and unprecedentedly improved imaging sensitivity and spatial resolution. Therefore, it is of great significance to design a new nanoplatform by integration of NIR-II optical imaging and drug delivery functions. Herein, a multifunctional nanoplatform based on GdPO4:Nd3+ yolk–shell sphere was developed for dual-modal in vivo NIR-II/X-ray bioimaging and pH-responsive drug delivery. The in vivo NIR-II bioimaging and real-time tracking presented that these probes were mainly accumulated in liver and spleen. Moreover, owing to the large X-ray absorption coefficient of Gd3+, these probes are successfully used as superior X-ray imaging agents than iobitridol. The in vivo toxicity assessments demonstrate the low biotoxicity of the GdPO4:Nd3+ spheres in living animals. More importantly, apart from the excellent dual-modal bioimaging, these yolk–shell-structured probes were also used as ideal nanotransducer for pH-responsive drug delivery of doxorubicin (DOX). These findings open up the opportunity of designing theranostic nanoplatform with integration of imaging-based diagnosis and therapy.

High Mass X-ray Binaries: Beacons in a Stormy Universe.

The discovery of gravity waves from the mergers of black hole binaries has focused the astronomical community on the high mass X-ray binaries (HMXBs) as the potential progenitors of close pairs of compact stars. This symposium gathered experts in observational and theoretical work for a very timely review of our understanding of the processes that drive the X-ray luminosity of the diverse kinds of binaries and what evolutionary stages are revealed in the observed cases. Here I offer a condensed summary of some of the results about massive star properties, the observational categories of HMXBs, their accretion processes, their numbers in the Milky Way and other galaxies, and how they may be related to the compact binaries that merge in a burst of gravity waves.

A REVERSE SHOCK IN GRB 160509A

ABSTRACT We present the second multi-frequency radio detection of a reverse shock in a γ-ray burst. By combining our extensive radio observations of the Fermi-Large Area Telescope γ-ray burst 160509A at z = 1.17 up to 20 days after the burst with Swift X-ray observations and ground-based optical and near-infrared data, we show that the afterglow emission comprises distinct reverse shock and forward shock contributions: the reverse shock emission dominates in the radio band at ≲10 days, while the forward shock emission dominates in the X-ray, optical, and near-infrared bands. Through multi-wavelength modeling, we determine a circumburst density of , supporting our previous suggestion that a low-density circumburst environment is conducive to the production of long-lasting reverse shock radiation in the radio band. We infer the presence of a large excess X-ray absorption column, N H ≈ 1.5 × 1022 , and a high rest-frame optical extinction, A V ≈ 3.4 mag. We identify a jet break in the X-ray light curve at , and thus derive a jet opening angle of , yielding a beaming-corrected kinetic energy and radiated γ-ray energy of erg and erg (1–104 keV, rest frame), respectively. Consistency arguments connecting the forward shocks and reverse shocks suggest a deceleration time of s ≈ T 90, a Lorentz factor of , and a reverse-shock-to-forward-shock fractional magnetic energy density ratio of . Our study highlights the power of rapid-response radio observations in the study of the properties and dynamics of γ-ray burst ejecta.

PrestoPronto: a code devoted to handling large data sets

The software PrestoPronto consist to a full graphical user interface (GUI) program aimed to execute the analysis of large X-ray Absorption Spectroscopy data sets. Written in Python is free and open source. The code is able to read large datasets, apply calibration, alignment corrections and perform classical data analysis, from the extraction of the signal to EXAFS fit. The package includes also programs with GUIs] to perform, Principal Component Analysis and Linear Combination Fits. The main benefit of this program is allow to follow quickly the evolution of time resolved experiments coming from Quick-EXAFS (QEXAFS) and dispersive EXAFS beamlines.

PEGylated NaLuF4: Yb/Er upconversion nanophosphors for in vivo synergistic fluorescence/X-ray bioimaging and long-lasting, real-time tracking

Simultaneous in vivo luminescence and X-ray bioimaging in a tissue or animal integrates the advantages of each single-modal imaging technology, and will find widespread application in biological and clinical fields. However, synergistic dual-modal bioimaging that utilizes a new generation of upconversion nanoprobes is still limited. In addition, investigations concentrated on in vivo biodistribution of these nanoprobes may contribute to diagnosis and treatment, but long-term in vivo tracking based on these nanoprobes is rarely reported. In this work, water-soluble NaLuF4: Yb/Er nanophosphors were prepared through modified one-pot simultaneous synthesis and surface modification method. Owing to the outstanding upconverting emissions and large X-ray absorption coefficient/K-edge value of Lu and doped Yb ions, the obtained nanoprobes were successfully used as luminescent nanoprobes and X-ray contrast agents for in vivo synergistic upconversion luminescence and X-ray bioimaging. The in vivo biodistribution of these nanoprobes were observed, and the results based on long-term tracking reveal that the as-prepared nanoprobes first aggregated in the lung of the mouse, transferred to the liver, and finally moved to the spleen.

Synergistic Dual-Modality in Vivo Upconversion Luminescence/X-ray Imaging and Tracking of Amine-Functionalized NaYbF4:Er Nanoprobes

In this work, the amine-functionalized NaYbF4:Er nanoparticles were developed as dual-modal nanoprobes for synergistic upconversion (UC) luminescence and X-ray imaging in a single system by a simple one-step method of simultaneous synthesis and surface modification. The water-soluble NaYbF4:Er nanoparticles present excellent green and dominant red UC emissions. The in vitro cell imaging shows that the high-contrast green and intense red UC emissions can be observed from HeLa cells treated with these nanoparticles, indicating the successful labeling of HeLa cells. Moreover, the localized spectra measured from HeLa cells and background presented significant green and dominant red UC emissions with the absence of any autofluorescence, further verifying that these nanoparticles can be successfully used as ideal probes for optical UC bioimaging with high contrast and non-autofluorescence. In addition, the amine-functionalized NaYbF4:Er nanoparticles maintained low cell toxicity in HeLa cells evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. More importantly, these amine-functionalized NaYbF4:Er nanoparticles can also be used as X-ray imaging, owing to the large X-ray absorption efficiency of the Yb ion. The synergistic in vivo UC and X-ray imaging present significant UC luminescence and X-ray signals in the same region of a nude mouse, and the two signals are matched very well, which provides direct evidence for simultaneous UC luminescence and X-ray imaging in a single compound of lanthanide-doped material. Moreover, ex vivo UC imaging shows that these nanoparticles are first accumulated in the lung and gradually translocated from the lung into the liver. These results demonstrate that the amine-functionalized NaYbF4:Er nanoparticles presented here are very attractive nanoprobes for dual-modal UC luminescence and X-ray imaging with low cytotoxicity, autofluorescence free, and synergistic combination of the advantages of the two imaging modalities.

A NEW DIAGNOSTIC OF ACTIVE GALACTIC NUCLEI: REVEALING HIGHLY ABSORBED SYSTEMS AT REDSHIFT &gt;0.3

We introduce the Mass-Excitation (MEx) diagnostic to identify active galactic nuclei (AGN) in galaxies at intermediate redshift. In the absence of near-infrared spectroscopy, necessary to use traditional nebular line diagrams at z>0.4, we demonstrate that combining [OIII]5007/Hbeta and stellar mass successfully distinguishes between star formation and AGN emission. The MEx classification scheme relies on a novel probabilistic approach splitting galaxies into sub-categories with more confidence than alternative high-z diagnostic diagrams. It recognizes that galaxies near empirical boundaries on traditional diagrams have an uncertain classification and thus a non-zero probability of belonging to more than one category. An outcome of this work is a system of statistical weights that can be used to compute global properties of galaxy samples. We apply the MEx diagram to 2,812 galaxies at 0.3<z<1 in the Great Observatories Origins Deep Survey North and Extended Groth Strip fields, and compare it to an independent X-ray classification scheme. We identify Compton-thick AGN candidates with large X-ray absorption, which we infer from the luminosity ratio between hard X-ray emission and [OIII]5007, a nearly isotropic tracer of AGN. X-ray stacking of sources that were not detected individually supports the validity of the MEx diagram and yields a very flat spectral slope for the Compton-thick candidates (Gamma~0.4, unambiguously indicating absorbed AGN). We present evidence that composite galaxies, which are difficult to identify with alternative high-redshift diagrams, host the majority of the highly-absorbed AGN. Our findings suggest that the interstellar medium of the host galaxy provides significant absorption in addition to the torus invoked in AGN unified models.

EIGHT γ-RAY PULSARS DISCOVERED IN BLIND FREQUENCY SEARCHES OFFERMILAT DATA

We report the discovery of eight gamma-ray pulsars in blind frequency searches using the LAT, onboard the Fermi Gamma-ray Space Telescope. Five of the eight pulsars are young (tau_c<100 kyr), energetic (Edot>10^36 erg/s), and located within the Galactic plane (|b|<3 deg). The remaining three are older, less energetic, and located off the plane. Five pulsars are associated with sources included in the LAT bright gamma-ray source list, but only one, PSR J1413-6205, is clearly associated with an EGRET source. PSR J1023-5746 has the smallest characteristic age (tau_c=4.6 kyr) and is the most energetic (Edot=1.1E37 erg/s) of all gamma-ray pulsars discovered so far in blind searches. PSRs J1957+5033 and J2055+25 have the largest characteristic ages (tau_c~1 Myr) and are the least energetic (Edot~5E33 erg/s) of the newly-discovered pulsars. We present the timing models, light curves, and detailed spectral parameters of the new pulsars. We used recent XMM observations to identify the counterpart of PSR J2055+25 as XMMU J205549.4+253959. In addition, publicly available archival Chandra X-ray data allowed us to identify the likely counterpart of PSR J1023-5746 as a faint, highly absorbed source, CXOU J102302.8-574606. The large X-ray absorption indicates that this could be among the most distant gamma-ray pulsars detected so far. PSR J1023-5746 is positionally coincident with the TeV source HESS J1023-575, located near the young stellar cluster Westerlund 2, while PSR J1954+2836 is coincident with a 4.3 sigma excess reported by Milagro at a median energy of 35 TeV. Deep radio follow-up observations of the eight pulsars resulted in no detections of pulsations and upper limits comparable to the faintest known radio pulsars, indicating that these can be included among the growing population of radio-quiet pulsars in our Galaxy being uncovered by the LAT, and currently numbering more than 20.

Sample Holder for Small-Angle X-ray Scattering Measurements and Density Fluctuation of Supercritical Xenon

We constructed a sample holder of Xe for small-angle X-ray scattering (SAXS) experiments. The holder was designed to attain a very small path length of a sample that corresponds to the large X-ray absorption of Xe. For the easy and convenient operation of the experiments in synchrotron radiation facilities, a cell was contrived so as to vary the path length despite the presence of a high-pressure sample inside. The path length varies from 0.05 to 3.5 mm. The holder is applicable not only to supercritical Xe but also to liquids, solutions and other supercritical fluids under highly pressured conditions using relatively low-energy X-rays. SAXS measurements were carried out for supercritical Xe in a wide density range. Density fluctuations for the fluid at various thermodynamic states were obtained from SAXS signals.

Enhanced relaxation of nanoparticle-bound supercoiled DNA in X-ray radiation

A therapeutic methodology was developed based on the large X-ray absorption cross-section of gold nanoparticles at high photon energies (>81 keV). Experimental results showed that the amounts of the relaxed circular supercoiled DNA (scDNA) for gold nanoparticle-bound scDNA were more than doubled compared to that for free scDNA under otherwise identical radiation conditions.

A Candidate of a Type 2 Quasi‐stellar Object atz = 0.9: Large X‐Ray Absorption with a Strong Broad Hα Emission Line

Deep hard X-ray and near-infrared observations of a type 2 radio-quiet quasi-stellar object (QSO) candidate at z = 0.9, AX J08494+4454, are reported. The 0.5-10 keV Chandra X-Ray Observatory spectrum of AX J08494+4454 is hard and is explained well with a power-law continuum absorbed by a hydrogen column density of (2.3 ± 1.1) × 1023 cm-2. The 2-10 keV luminosity of the object is estimated to be 7.2 × 1044 ergs s-1, after correcting the absorption, and reaches hard X-ray luminosities of QSOs. The large X-ray absorption and the large intrinsic luminosity support the original identification of AX J08494+4454 as a type 2 radio-quiet QSO. Nevertheless, the deep Subaru/IRCS J-band spectroscopic observation suggests the presence of a strong broad Hα emission line from AX J08494+4454. If real, the broad Hα emission line has a velocity width of 9400 ± 1000 km s-1, which corresponds to a typical broad Balmer line velocity width of a luminous QSO. The existence of the strong broad Hα line means that the object is not a type 2 QSO but a luminous cousin of a Seyfert 1.9 galaxy in the source-frame optical spectrum. The Balmer decrement of broad lines and the broad Hα emission to the hard X-ray luminosity ratio suggest that the nucleus is affected by dust extinction with an AV of 1-3 mag in the optical wavelength. Optical colors and faint optical magnitudes of AX J08494+4454 are consistent with the model. The estimated amount of dust extinction is much smaller than that expected from the X-ray column density (AV = 130 ± 60 mag).

Fabrication of a Tantalum-Based Josephson Junction for an X-Ray Detector

We have fabricated a tantalum-based Josephson junction for an X-ray detector. The tantalum layer was selected for the junction electrode because of its long quasiparticle lifetime, large X-ray absorption efficiency and stability against thermal cycling. We have developed a buffer layer to fabricate the tantalum layer with a body-centered cubic structure. Based on careful consideration of their superconductivity, we have selected a niobium thin layer as the buffer layer for fabricating the tantalum base electrode, and a tungsten thin layer for the tantalum counter electrode. Fabricated Nb/AlOx–Al/Ta/Nb and Nb/Ta/W/AlOx–Al/Ta/Nb Josephson junctions exhibited current–voltage characteristics with a low subgap leakage current.

Transduction principles of a-Si:H Schottky diode X-ray image sensors

This paper reports on the operating principles, along with design and fabrication considerations, of a novel direct conversion X-ray image sensor based on Mo/a-Si:H Schottky diodes. The choice of Mo as a Schottky contact follows from its relatively low intrinsic mechanical stress, temperature stability, and relatively large X-ray absorption. Furthermore, it is compatible with the standard a Si:H thin film transistor (TFT) technology. Here, the TFTs are intended for use as switching elements in large area imaging applications. Results of X-ray sensitivity are presented for a broad range of X-ray energies (20-100 keV), along with the influence of various geometric and operating parameters on X-ray sensitivity. The detector shows a linear response with respect to the number of absorbed X-ray photons. Analysis shows that the detector sensitivity reaches its maximum for a Mo layer thickness of around 500 nm at 60 kVp. Measurements, performed in a medical environment, demonstrate the feasibility of the detector for large area medical imaging applications.