Large Foot Research Articles

Analysis of Serial Foot Radiographs to Determine Foot Height Multipliers.

The multiplier method is an arithmetic calculation that estimates the amount of growth remaining until skeletal maturity. When predicting lower limb length discrepancy, differences in foot height are added to femur and tibia discrepancies. Foot height multipliers have not been calculated using radiographic measurements, so it is unclear whether foot height develops at the same pace as the femur and tibia. This study used serial images to calculate foot height multipliers and compared them to published lower limb and foot length multipliers. The Bolton Brush radiograph collection was used to measure foot height on the lateral foot view. Multipliers were calculated for ages with at least 10 serial study visits. 212 patients (2195 radiographs) were included in the study (102 female, 110 male patients). Foot height multipliers were calculated for ages 0 to 17 years (females) and 0 to 18 years (males). Multipliers decreased with age, but qualitatively plateau at age 13 (females) and age 15 (males). Lower extremity multipliers have a more dramatic growth curve, indicating comparatively greater lower extremity growth after birth. However, when comparing the limb length discrepancy calculation using the lower extremity multiplier versus the foot height multiplier for the foot portion, the difference was negligible. This paper provides a database of foot height multipliers. Foot height seems to grow on a different trajectory than other lower limb components, confirming that one should consider separate multiplier values. The difference created by the foot height multiplier versus the lower extremity multiplier appears to be modest. Separate use of the foot height multiplier may only be necessary for young children with large foot height discrepancies, but further study to confirm the lack of impact of the foot height multiplier on limb length discrepancy calculations is needed. Our data were derived from normal children, so it is unknown if the presence of a talo-calcaneal coalition would affect foot height on the involved side. Level III-retrospective comparative study.

Anterolateral thigh free flap surgery for medial malleoli fracture with extensive dorsal foot skin defect: A case report

Severe foot deformities, especially those affecting the dorsum of the foot, can make it difficult to perform daily activities. For example, mild pain when walking can be felt on the dorsal aspect of the foot, and toe contractures can make it difficult to wear non supportive shoes. Reconstructive surgeons face a great deal of difficulty in providing a suitable flap in accordance with the "like for like" reconstructive principle. The best outcomes for reconstructing small- to medium-sized dorsal foot lesions have been reported using local flaps and pedicled flaps. Reconstruction of large dorsal foot deformities is, however, hardly studied. In this work, we report our experience reconstructing large dorsal foot lesions using the free anterolateral thigh (ALT) flap.

Comparison of foot pressure distribution and foot kinematics in undulatory underwater swimming between performance levels

ABSTRACT This study aimed to elucidate the foot kinematics and foot pressure difference characteristics of faster swimmers in undulatory underwater swimming (UUS). In total, eight faster and eight slower swimmers performed UUS in a water flume at a flow velocity set at 80% of the maximal effort swimming velocity. The toe velocity and foot angle of attack were measured using a motion capture system. A total of eight small pressure sensors were attached to the surface of the left foot to calculate the pressure difference between the plantar and dorsal sides of the foot. Differences in the mean values of each variable between the groups were analysed. Compared to the slower swimmers, the faster swimmers exhibited a significantly higher swimming velocity (1.53 ± 0.06 m/s vs. 1.31 ± 0.08 m/s) and a larger mean pressure difference in the phase from the start of the up-kick until the toe moved forward relative to the body (3.88 ± 0.65 kPa vs. 2.66 ± 1.19 kPa). The faster group showed higher toe vertical velocity and toe direction of movement, switching from lateral to medial at the time of generating the larger foot pressure difference in the up-kick, providing insight into the reasons behind the foot kinematics of high UUS performance swimmers.

Nonunion After First Metatarsophalangeal Joint Arthrodesis: The Association With Shoe Size.

First metatarsophalangeal joint (MTPJ) arthrodesis is a common treatment for various foot conditions, with nonunion as a frequent complication. The incidence of nonunion varies widely in the literature. In particular, males have a higher risk of nonunion than females.This is possibly due to biomechanical and anatomical differences, as men have on average larger feet than women. This study therefore aims to explore whether shoe size, as a proxy for foot size, affects nonunion rates and could explain the gender disparity in nonunion rates. An exploratory analysis of retrospectively collected data from patients who underwent primary first MTPJ arthrodesis in a single secondary hospital between January 2012 and December 2019. Additional data on body weight, height, and shoe size were prospectively collected from patients. Among 261 included patients, 57 (21.8%) experienced nonunion. Nonunion incidence was higher in males (18, 26.9%) than in females (39, 20.1%). Self-reported shoe size showed no significant association with nonunion in both univariate and multivariate analyses. The study's findings suggest that shoe size, as a proxy for foot size, is not associated with nonunion after the first MTPJ arthrodesis. Despite observing a gender difference in nonunion rates, this disparity could not be explained by shoe size. Shoe size as a proxy for foot size appears to have no clinical association with nonunion following the first MTPJ arthrodesis.

Intersession reliability of center of pressure measurement during bipedal standing with different foot placement angles

IntroductionThe foot placement is a determinant of the base of support and influences standing balance. The reliability of postural stability tests with different foot placement angles is unclear. Research questionTo determine and compare the intra- and inter-day reliability of the center of pressure-based postural stability while standing with different foot placement angles. MethodTwenty-five healthy adults (16 females and 9 males; age: 29 ± 6 years) completed 70 s trials of eyes open and eyes closed stability tests with 0°, 15°, 30°, and 45° angles between the feet while standing on a forceplate in three sessions: two sessions were in the same day, and the third session was one-week apart. The repeatability of measurements was tested using analysis of variance, interclass correlation, and standard error of measurements. ResultThroughout the three study sessions, there was no difference in postural stability while participants stood with different foot placement angles. The interclass correlation scores ranged from 0.71 to 0.96, the standard error of measurements ranged from 2.1% to 12.9%, and no significant systematic changes (p < 0.05) occurred between the testing sessions for any foot placements. Standing with a 45° angle between the feet with closed eyes showed higher reliability values than other conditions. The intra-day reliability scores were greater than inter-day reliability. DiscussionThe relative reliability of postural stability could be impacted by foot placement angles, which might alter ankle mobility and base of support dimensions. The advantages of larger foot placement angles on improving the relative reliability of postural stability could be better demonstrated in healthy people under challenging conditions such as standing with closed eyes. ConclusionStanding with foot placement angles between 0° and 45° are reliable and a quantitative assessment of the center of pressure could be used to monitor the changes in postural stability between sessions.

Free medial plantar flap connection with a posterior tibial artery flap and its modification for combined dorsal and plantar foot defects - two case reports.

Reconstruction of large soft tissue foot defects were considered a difficult issue due to weight-bearing function of the foot. The reconstruction becomes more difficult when both plantar and dorsal soft tissues are involved. The options for the reconstruction were variable, in 2016 Hao Wu et al. presented a combined flap for coverage of combined fore-foot plantar and dorsal soft tissue defects. We used combined flaps in two cases and present our experience in this article.

THU182 Widening The Spectrum Of ABCC8-related Disease: Insulin-mediated Pseudoacromegaly

Abstract Disclosure: I.F. Machado: None. B.B. Mendonca: None. A. Latronico: None. M.Y. Nishi: None. L.G. Gomes: None. Introduction: Insulin-mediated pseudoacromegaly is a rare condition characterized by acromegaloid phenotype without excessive GH secretion in the context of severe hyperinsulinemia. Case report: A 10.5 years old girl with tall stature, obesity, acanthosis nigricans, neurosensorial hearing deficiency and acromegaloid features was referred for clinical investigation. She was born of non-consanguineous parents, full-term, with normal birth weight and stature. She had no history of neonatal hypoglycemia or in infancy. At six years of age, she presented marked accelerated growth velocity and weight gain resulting in bilateral slipped femoral epiphysis. She developed thelarche at 7 years old, and was treated with gonadotropin releasing hormone agonist (GnRHa) from 8-10.5 years. Hearing deficiency was diagnosed at 7 years of age. Her family history was remarkable for paternal sudden cardiac death at age 35. At physical examination, she had an acromegaloid facial appearance with a prominent forehead and jaw, large hands and feet, and severe acanthosis nigricans in neck and axillae. Her weight and height were 99.5 kgs (Z 8.8) and 170 cm (Z 4.6), respectively; target height was 1.66 m (Z 0,72) and BMI was 34.4 (Z 3.5). Her breast and pubic hair development were Tanner stage IV. Laboratory exams showed normal IGF-1 and random GH levels. There was an abnormal response of GH (2.63 ng/mL) following an oral glucose tolerance test (OGTT), considered as false positive in the context of obesity and puberty. Her brain magnetic resonance was normal. She had a hemoglobin glycated of 6.1% and very high basal insulin levels of 98 µUI/mL with a normal glucose value of 81 mg/dL and OGTT-120 minutes insulin levels &amp;gt; 1000 µUI/mL with glucose of 113 mg/dL. Exome sequencing analysis showed a heterozygous missense ABCC8 variant c.622G&amp;gt;A p.(Glu208Lys), located in an exonic hotspot, and allele frequency absent from gnomAD databases. The ACMG classified this variant as pathogenic. Pseudoacromegaly, a heterogeneous condition, is caused by multiple genetic and pathophysiological backgrounds. In insulin-mediated pseudoacromegaly, the defects are mainly associated with postreceptor insulin signaling and action. We described a new type of hyperinsulinemic pseudoacromegaly caused by a mutation in the ABCC8 gene, which encodes the sulfonylurea receptor, a member of the K(ATP) channel superfamily. This gene is associated with congenital hyperinsulinemia causing hypoglycemia, generally when in homozygous state. This clinical report illustrates a new phenotype associated with ABCC8 mutation, and identifies a new genetic cause of hyperinsulinemic pseudoacromegaly. Conclusion: We described a patient with insulin-mediated pseudoacromegaly associated with neurosensorial hearing deficiency caused by a dominant variant in the ABCC8 gene, defining a new genetic cause of this intriguing disorder. Presentation: Thursday, June 15, 2023

Study on Closely Spaced Asymmetric Footings Embedded in a Reinforced Soil Medium

In practice, footings are rarely laid on the surface or at ground level; usually, they are embedded in the soil medium. Most studies focus on surface footings. This research examines the behavior of two interfering asymmetric footings while considering their widths to be dissimilar and the effect of embedment depth to enhance the ultimate bearing capacity and limit the settlement within the working range. This was evaluated through the finite element method of the ABAQUS software. The soil was assumed to have a Mohr-Coulomb failure, and the asymmetry corresponded to the footing widths. The results are presented in terms of interference factors, i.e., the ultimate bearing capacity (UBC) and the settlement, which are defined as the UBC/settlement ratio of the left/right footing in the presence of the other one placed on reinforced soil. This, in comparison with an identical isolated footing on unreinforced soil. Interference is more significant in small footings than in large ones. Due to behavioral variations, the bearing capacity and settlement are different. This effect increases with an increase in the width of large footings, and the interference factors decrease with an increase in the embedment depth of the footings. When the right footing width is twice that of the other and considering one layer of reinforcement and soil friction angles of 30º and 40º, the percent increments in the bearing capacity of interfering left footings, for a spacing of 0,5 times the left footing width, are 104 and 148%, respectively.

Sound barrier behavior of geopolymer composite manufactured from industrial waste

Noise pollution is an invisible hazard faced in industries, roads, and public places etc., and has become part of daily life. Noise affects the psychology and physiology of animals and humans and can lead to accidents and health issues. Noise can be reduced by using active or passive materials. Active mediums are in which enormous amount of external energy is used to balance the noise energy, whereas in passive medium sound is absorbed such as by using insulating materials. Conventionally, passive sound barrier panels made of concrete are used, which involve energy intensive manufacturing processes as they use Ordinary Portland Cement (OPC). The concrete sound barrier panels have a large carbon foot print as it releases carbon dioxide (CO2) during manufacture of OPC and during hydration of concrete. The global warming is caused due to emission of greenhouse gases mainly comprising of carbon di oxide. The cement industry emits 5 to 8 % of the world’s CO2 emissions and thus an alternate building material is required. The search for an ecofriendly green binding material to replace cement leads to discovery of geopolymer. Geopolymers are ceramic materials comprising of polymers made of inorganic aluminosilicate and fabricated by alkali activation of aluminosilicates. In this research work, the induction furnace (IF) slag and Class F fly ash are utilized along with manufactured sand (M Sand) an alternative material for the river sand, as fine aggregate. The environmental advantage of this material is that the ingredients are industrial waste and the geopolymer has negligible carbon foot print. The geopolymer composite specimens were subjected to sound absorption test using impedance tube studies and found to exhibit an increased sound absorption coefficient (α) between 0.2 and 0.35 in the frequency range of 1200 Hz to 6300 Hz. This study establishes that the geopolymer manufactured using industrial waste material can be effectively utilized as sound absorption material and can assist in mitigating noise pollution.

Functional and contour restoration in severely injured extremities - our approach to reconstruct composite (Multizonal) injuries of foot and ankle

BackgroundCoverage of ankle and foot defects has been challenging. This study highlights the importance of microsurgical free tissue transfer as an opportunity for a surgeon to deal with composite foot defects with variable etiology. MethodA retrospective case review of 28 patients with large Multizonal foot defects resulting from trauma and tumor resections presented to tertiary care hospitals from 2008-to 2021. All defects were reconstructed by free flaps. 14 patients had ALT flaps, 4 underwent free fibula flaps, and 6 had LD flaps and 4 Rectus Abdominis free flaps. Different modalities have been reviewed by literature for the type of flap used, zone involvement, and age groups. Result26 patients were male and 2 females. Most of our patients were adults presenting post-trauma including n ​= ​21 (75%) road traffic accidents n ​= ​17 (60.7%), mine blast injury n ​= ​4 (14.2%), and malignancy in n ​= ​3 (10.7%). Age range was from 5 years to 75 years. Most of the patients had involvement of subunits 3 and 4 followed by a combination with other sub-units. After free microsurgical tissue transfer, 2 patients needed immediate exploration, one had arterial compromise and one had venous insufficiency. All flaps survived. 3 patients underwent flap debulking in the follow-up period. All patients were followed for 2 years and returned to daily activities and near to normal ambulation. ConclusionMicrosurgical free tissue transfer has not only proven its role in post-traumatic composite foot defects but also in malignancies where resection with free margins followed by foot reconstruction poses a major challenge.

First Find of a Frozen Mummy of the Fossil Don Hare Lepus tanaiticus (Leporidae, Lagomorpha) from the Pleistocene of Yakutia

Until recently, only bone remains of Don hares, which went extinct in the Holocene, were known. For the first time, the mummy of an adult hare, identified as a Don hare, has made it possible to expand our understanding of this species and its morphological adaptations to living conditions in the Arctic steppes of the Pleistocene of Yakutia: large body length, short ears and feet, powerful locomotor apparatus of the hind limbs, hard hair brushes on the feet, and excellent heat-shielding properties of the fur, including the specific microstructure of the hairs.

FIRST FIND OF THE FROZEN MUMMY OF THE FOSSIL DON HARE &lt;i&gt;LEPUS TANAITICUS&lt;/i&gt; (LEPORIDAE, LAGOMORPHA) FROM THE PLEISTOCENE OF YAKUTIA

Until recently, only the bone remains of the Don hares, extinct in the Holocene, were known. For the first time, the mummy of an adult hare, identified as the Don hare, has made it possible to expand the understanding of this species and its morphological adaptations to living conditions in the Arctic steppes of the Pleistocene of Yakutia: large body length, short ears and feet, powerful locomotor apparatus of the hind limbs, hard hair brushes on the feet, excellent heat-shielding properties of the fur, including the specific microstructure of the hairs.

Feature Selection, Construction, and Validation of a Lightweight Model for Foot Function Assessment During Gait With In-Shoe Motion Sensors

Identifying and monitoring overpronation and oversupination in the long term during activities of daily living is essential for people’s ambulatory health. Using an in-shoe motion sensor (IMS) with power-saving functions is a potential solution. In this study, we challenged the development of an estimation model of foot function using the foot center of pressure excursion index (CPEI) as an index via linear multivariate regression, which is sufficiently light for this type of IMS. Data collected from 65 and 17 participants were involved in model construction and validation, respectively. We validated ten scenarios simulating daily living activities, including walking on different surfaces, using different shoes, with or without carrying a bag, and indoors and outdoors. We applied statistic parametric mapping (SPM) to determine significant predictors and performed our original feature selection algorithm, leave-one-subject-out LASSO, to compress the volume of the predictors. We successfully discovered significant sex-specific predictors for foot function estimation from foot motion and constructed large effect-sized sex-specific foot function estimation models that achieved high-precision CPEI estimation. In the validation, the model successfully estimated a maximum of 99.0% and 100.0% males’ and females’ data under the same experimental conditions with the training data and 92.8–100.0% and 85.8–100.0% data in different scenarios. The constructed models are effective and possible to provide applications for long-term foot function monitoring by using an IMS.

Spider‐Inspired, Fully 3D‐Printed Micro‐Hydraulics for Tiny, Soft Robotics

AbstractMany arachnids use internal hemolymph pressure to actuate extension in their leg joints. The inherent large foot displacement‐to‐body length ratio that arachnids can achieve through hydraulics relative to muscle‐based actuators is both energy and volumetrically efficient. Until recent advances in nano/microscale 3D printing with two‐photon polymerization (2PP), the physical realization of synthetic complex ‘soft’ joints would have been impossible to replicate and fill with a hydraulic fluid into a sealed sub‐millimeter system. Inspired by nature, the smallest scale 3D‐printed hydraulic actuator (4.9 × 10−4 mm3) by more than an order of magnitude is demonstrated. The use of stiff 2PP polymers with micron‐scale dimensions enable compliant membranes similar to exoskeletons seen in nature without the requirement for low‐modulus materials. The bio‐inspired system is designed to mimic similar hydraulic pressure‐activated mechanisms in arachnid joints utilized for large displacement motions relative to body length. Using variations on this actuator design, the ability to transmit forces with relatively large magnitudes (milliNewtons) in 3D space is demonstrated, as well as the ability to direct motion that is useful towards microrobotics and medical applications. Microscale hydraulic actuation provides a promising approach toward the transmission of large forces and 3D motions at small scales, previously unattainable in wafer‐level 2D microelecromechanical systems (MEMS).

Analysis of Diabetic Foot Deformation and Plantar Pressure Distribution of Women at Different Walking Speeds.

Official guidelines state that suitable physical activity is recommended for patients with diabetes mellitus. However, since walking at a rapid pace could be associated with increased plantar pressure and potential foot pain, the footwear condition is particularly important for optimal foot protection in order to reduce the risk of tissue injury and ulceration of diabetic patients. This study aims to analyze foot deformation and plantar pressure distribution at three different walking speeds (slow, normal, and fast walking) in dynamic situations. The dynamic foot shape of 19 female diabetic patients at three walking speeds is obtained by using a novel 4D foot scanning system. Their plantar pressure distributions at the three walking speeds are also measured by using the Pedar in-shoe system. The pressure changes in the toes, metatarsal heads, medial and lateral midfoot, and heel areas are systematically investigated. Although a faster walking speed shows slightly larger foot measurements than the two other walking speeds, the difference is insignificant. The foot measurement changes at the forefoot and heel areas, such as the toe angles and heel width, are found to increase more readily than the measurements at the midfoot. The mean peak plantar pressure shows a significant increase at a faster walking speed with the exception of the midfoot, especially at the forefoot and heel areas. However, the pressure time integral decreases for all of the foot regions with an increase in walking speed. Suitable offloading devices are essential for diabetic patients, particularly during brisk walking. Design features such as medial arch support, wide toe box, and suitable insole material for specific area of the foot (such as polyurethane for forefoot area and ethylene-vinyl acetate for heel area) are essential for diabetic insole/footwear to provide optimal fit and offloading. The findings contribute to enhancing the understanding of foot shape deformation and plantar pressure changes during dynamic situations, thus facilitating the design of footwear/insoles with optimal fit, wear comfort, and foot protection for diabetic patients.

Is foot size getting bigger across the generations?

This study aimed to evaluate whether there was a variation in foot size between generations. This is a general population survey study conducted in Turkey between January and July 2022. The questionnaire consisted of five questions, including age, gender, height, weight, and shoe size. Survey questions were prepared on a digital platform, and participants completed the survey online via their computers or smartphones. The European shoe sizing system was used for shoe sizes. Four groups were formed (1st generation 18–25 years old, 2nd generation >25–50 old, 3rd generation, >50–75 years old and 4th generation >75 years old), from the new generation to the old generation. A total of 3196 subjects, 1425 (44.6%) women and 1771 (55.4%) men, were included in this study. The mean age of women was 41.6 ± 14.3 (range 18 to 97) years, and the mean age of men was 42.9 ± 13.2 (range 18 to 99) years. While height-weight adjusted foot size did not differ between generations in the female gender (p = 0.412), adjusted foot sizes were found to differ between generations in men (ANCOVA test p < 0.001). The youngest generation had larger foot sizes than the 2nd, 3rd, and 4th generations (p < 0.001, p < 0.001, and p = 0.009, respectively).The male foot size in the new generation is getting bigger independent of height and weight.Level of Clinical Evidence: 3

Individual yield nowcasting for residential PV systems

Due to the inherent uncertainty in photovoltaic (PV) energy generation, an accurate power forecasting is essential to ensure a reliable operation of PV systems and a safe electric grid. Machine learning (ML) techniques have gained popularity on the development of this task due to its increased accuracy. Most literature, however, focuses only on less than 5 PV systems during training process, which does not ensure generalization to unseen systems. When in presence of a large feet, regional forecasts are the norm. Nevertheless, none of these approaches are usable when it comes to monitoring residential PV systems. In this work, we propose a single ML model that is able to predict the individual power of a large fleet of 1102 PV systems. XGBoost algorithm was selected as the most suitable algorithm for the task of PV yield nowcasting due to its performance and ease of use. This algorithm obtains Mean Absolute Error (MAE) of 0.877 kWh (considering an average system size of 4.44 kWp) and Mean Absolute Percentage Error (MAPE) of 23% for hourly data aggregated to daily values. XGBoost predictions for individual PV systems are on average two times better than currently used commercial software. We discuss the lack of a suitable loss function that can combine absolute and relative errors for residential PV yield forecasting. We also point out the lack of an adequate metric to compute the error made on the predictions and provide hints on developing a suitable one.

Addressing prey naivety in native mammals by accelerating selection for antipredator traits.

Harnessing natural selection to improve conservation outcomes is a recent concept in ecology and evolutionary biology and a potentially powerful tool in species conservation. One possible application is the use of natural selection to improve antipredator responses of mammal species that are threatened by predation from novel predators. We investigated whether long-term exposure of an evolutionary naïve prey species to a novel predator would lead to phenotypic changes in a suite of physical and behavioral traits. We exposed a founder population of 353 burrowing bettongs (Bettongia lesueur) to feral cats (Felis catus) over 5 years and compared the physical and behavioral traits of this population (including offspring) to a control (non-predator exposed) population. We used selection analysis to investigate whether changes in the traits of bettongs were likely due to phenotypic plasticity or natural selection. We also quantified selection in both populations before and during major population crashes caused by drought (control) and high predation pressure (predator-exposed). Results showed that predator-exposed bettongs had longer flight initiation distances, larger hind feet, and larger heads than control bettongs. Trait divergence began soon after exposure and continued to intensify over time for flight initiation distance and hind foot length relative to control bettongs. Selection analysis found indicators of selection for larger hind feet and longer head length in predator-exposed populations. Results of a common garden experiment showed that the progeny of predator-exposed bettongs had larger feet than control bettongs. Results suggest that long-term, low-level exposure of naïve prey to novel predators can drive phenotypic changes that may assist with future conservation efforts.

Reverse Peroneal Artery Flap-A Workhorse Flap for Reconstruction of Large, Distal Defects of Ankle and Foot.

Background Reconstruction of large foot and ankle defects is a difficult task due to less available local soft tissue and more critical from functional point of view. To overcome the limitations associated with locoregional flaps and free flaps, reverse peroneal artery (RPA) flap was selected and its usefulness in reconstruction of distal large defects of the ankle and foot and its complications were studied. Materials and Methods This is a prospective observational study done in 20 patients treated as cohort within 2 years and 8 months from January 2018 to August 2020. Large defects of foot and ankle were reconstructed with RPA flap and evaluated for its usefulness. Three cases were evaluated with computed tomography angiography postoperatively, to assess the vascular pattern. Conclusion RPA flap is a versatile and very reliable flap for the reconstruction of large and distal defects of foot and ankle. It is safely done in children and in acute trauma without any major complications.

The impact of local muscle fatigue and foot strike techniques on kinematic features and plantar pressure distribution while walking

Although numerous studies have been performed, there are no clear findings providing a meaningful statement about how foot strike changes as a result of muscular fatigue. In studies on running fatigue, it is not possible to differentiate which kinematic or kinetic changes are a direct result of local muscle fatigue and varied speeds. This study aimed to investigate the effect of foot strike technique and localized muscle fatigue of the plantar and dorsal flexors on plantar pressure distribution and selected kinematic features of treadmill running. Twenty-six voluntary forefoot and rearfoot runners of similar age and body mass participated in the study. Each group completed two tests with a time interval of 3-7 days. The kinematic data was measured with the help of a three-dimensional measuring and analysis system while the volunteers ran on the treadmill. The fatigue protocol included an isometric maximal force test and an isokinetic endurance test. In order to check the differences, a variance analysis with repeated measurements was used. The strength values of the two groups of runners showed significant average differences in the plantar flexors in the endurance test and in the fatigue index for both the left and right legs. The results of the strength values are surprising because the plantar flexors of this group of runners should be well-trained due to the forefoot strike during regular running. In response to fatigue, the pressure maxima decreased under the exposed foot regions, i.e. under the forefoot at forefoot strike and under the heel at rearfoot strike. The two groups of runners differed in foot angle at foot-on with higher values measured in the forefoot runners. The larger foot angle of the forefoot runners improved shock absorption and can thus reduce the risk of injury.