Objective The Female Sexual Function Index (FSFI) was used to investigate the sexual life quality of patients who got laparoscopic peritoneal vaginoplasty of LuohuⅡ, so as to take measures to improve patients postoperative quality of life. Methods A total of 106 cases undergoing laparoscopic peritoneal vaginoplasty of LuohuⅡ were selected from January 2012 to March 2013.All patients got the questionnaire survey by FSFI and the FSDS-R questionnaire to evaluate the sexual function and psychological states. According to the existing problems, the intervention measures and health guidance were given to patients. And one year after surgery, their sexual function was evaluated again. Results The length of vagina was (12.29±1.67) cm, which was significantly longer than before (t=2.825, P<0.05). The sexual desire, sexual arousal, sexual orgasm, sexual satisfaction, sexual pain and total score of FSFI were (4.0±0.4), (4.2±0.4), (4.5±0.5), (4.1±0.7), (5.0±0.5), (4.6±0.5) and (29.7±1.2), which were significantly better than those before (t=7.64, 3.77, 6.27, 8.14, 8.78, 7.92, 36.13, respectively; P<0.01). Conclusions The sexual satisfaction of patients is increased after intervention. The patients with laparoscopic peritoneal vaginoplasty generally have sex problems and lack of the confidence, and effective intervention can improve the sexual life quality and satisfaction, as well as self-confidence of patients. Key words: Laparoscopic peritoneal vaginoplasty; LuohuⅡ; Quality of sexual life; Satisfaction