The mindful state is commonly characterized by an elevated awareness of the present moment. An intriguing and rather widespread phenomenon that requires the attention to the present moment is Synchronicity Awareness. This phenomenon refers to the sense of a profound psychological connection between an internal event (e.g., thought, image, or dream) and external events. Whereas mindfulness and its underlying cognitive processes have been well documented, synchronicity awareness, despite its deep roots, has been scarcely examined empirically, and little is known about the cognitive mechanisms underlying it. The present study aimed to further validate the recently developed Synchronicity Awareness and Meaning Detection (SAMD) scale and explore its potential relationship with various mindfulness measures. To this end, 572 participants engaged in an online survey, incorporating the SAMD, Five Facets of Mindfulness Questionnaire, Mindful Awareness and Attention Scale, Langer's Mindfulness Scale, and Encoding Style Questionnaire. The results revealed that synchronicity awareness, meaning detection, and mindfulness are distinct constructs. A significant association between synchronicity and core facets of mindfulness was observed, indicating that participants with higher SAMD scores were more sensitive to inner sensations, more novelty-seeking, and engaged in their actions. Additionally, SAMD scores were linked to internal encoding style, suggesting a top-down processing of experiences. However, synchronicity was not associated with outwards-directed mindful awareness, suggesting that it might involve an intrinsic attentional process, influenced by internal cues. Theoretical and practical implications are discussed.