Land-use change is one of the focal processes in Earth system models because it has strong impacts on terrestrial biogeophysical and biogeochemical conditions. However, modeling land-use impacts is still challenging because of model complexity and uncertainty. This study examined the results of simulations of land-use change impacts by the Model for Interdisciplinary Research on Climate, Earth System version 2 for long-term simulations (MIROC-ES2L) conducted under the Land-Use Model Intercomparison Project protocol. In a historical experiment, the model reproduced biogeophysical impacts such as decreasing trends in land-surface net radiation and evapotranspiration by about 1970. Among biogeochemical impacts, the model captured the global decrease of vegetation and soil carbon stocks caused by extensive deforestation. By releasing ecosystem carbon stock to the atmosphere, land-use change shortened the mean residence time of terrestrial carbon and accelerated its turnover rate, especially in low latitudes. Future projections based on Shared Socioeconomic Pathways indicated substantial alteration of land conditions caused primarily by climatic change and secondarily by land-use change. Sensitivity experiments conducted by exchanging land-use data between different future projection baseline experiments showed that, at the global scale, the anticipated extent of land-use conversion would likely play a modest role in the future terrestrial radiation, water, and carbon budgets. Regional investigations revealed that future land use would exert a considerable influence on runoff and vegetation carbon stock. Further model refinement is required to improve its capability to analyze its complicated terrestrial linkages or nexus (e.g., food, bioenergy, and carbon sequestration) to climate-change impacts.