The increase of the land surface temperature (LST) caused by an urban expansion poses a great threat to the humanity and society. However, the heating characteristics of built-up land and the environmental impacts on these mechanisms remain poorly understood over large areas. Therefore, the change trend (k) and structural distribution of LST during the process of increasing the built-up area in 172 cities in China was quantified. Using correlation analysis and statistical methods to analyze the correlation and possible driving characteristics of influencing factors (climate, topography, land use type, and soil) on k. The results indicated that k varied from −5.955 to 8.240 and showed a spatial characteristic of small in the northwest and large in the southeast. The research emphasized the heating difference of built-up land varied significantly in cities with different natural environmental conditions, with the maximum difference reaching 6 °C. The heating mechanism of built-up land under the interference of influencing factors was explained from the perspective of land surface heat flux, and the mitigation strategies for urban temperature were proposed. Besides, the threshold for the impact of environmental factors on the heating of built-up land was found, which provides a reference for environment-adapted urban design and planning standards tailored by considering the specific characteristics of each city.
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