Global vegetation greening during recent decades has been observed from various remote sensing data. The global and regional climate can be altered by an increase in carbon storage, as well as changes in land surface albedo (LSA) and evaporation. However, the LSA changes induced by global vegetation greening are still not clear, and contrasting responses of LSA to vegetation changes were reported in previous studies. In this study, we analyzed the LSA in response to global vegetation greening using the Global Land Surface Satellite (GLASS) data and a vegetation-induced LSA change model. The results showed that vegetation greening trends could be observed worldwide, which resulted in contrasting LSA responses at regional scales (LSA increased as leaf area index (LAI) increased, or LSA decreased as LAI increased). Moreover, these contrasting LSA responses to global vegetation greening were effectively explained by the albedo difference between a vegetation and soil background. The results provide new insights into the relationship between LSA changes and global vegetation dynamics, and can support recommendations for policies of vegetation protection, and large-scale afforestation and deforestation.