Acute dacryocystitis in neonates is an emergency condition that should be taken seriousely [1]. We report a case of a 25-day-old male newborn with inflammatory swelling of the inner canthus of the left eye. The ophtalmological examination revealed unilateral lacrimal sac abscess with compression of the lacrymal sac (Figure 1). Orbital CT scan confirmed the presence of abscess, with mild preseptal cellulitis (Figure 2), no signes of ethmoidal sinusitis were showen. The newborn was hospitalized and intravenous C3G antibiotherapy was started. Over the next day, we noticed an external fistula formation. General and local antibiotic therapy was continued for a short time, with a gentle massage of the lacrimal sac [2]. The evolution was marked by a progressive regression of the swelling as showed, and no recurrence of the condition was diagnosed in the follow up (Figure 1). This case is a reminder for our clinical practice to think of the presence of a potentiel dacryocyctocele in every acute dacryocystitis in neonates.