Abstract With the interaction and development of economy and environment, generally speaking, environmental Kuznets Curve mainly refers to the deterioration of environmental quality of a country or corresponding region with economic growth. When the economic development reaches a certain level, the environmental quality will be further improved. However, due to the modern economy and the policy factors of corresponding countries and regions, the correlation between the internal differences of regional economy and environmental pollution does not necessarily follow the conventional inverted U-shaped distribution. Based on the Kuznets curve, this paper makes a quantitative linear regression analysis of economic growth and environmental pollution in a certain region, and verifies the particularity of the regional Kuznets curve. At the same time, this paper will fully consider the policy factors, science and technology development factors, industrial scale and structure factors in the actual analysis of the relevant regions. The experimental results also prove that the research results of this paper have high accuracy for analyzing the correlation between the economy and the environment in a specific region, and the accuracy rate is about 5% higher than that corresponding to the traditional Kuznets curve. Finally, according to the actual situation of the region, this paper puts forward some suggestions and specific measures.