In order to successfully simulate the crushing process of iron ore in a gyratory crusher, it is crucial to precisely model the iron ore based on the bonded-particle model, this requires reasonably calibrated micromechanical parameters in the model. In this study, a calibration method for iron ore BPM bonding parameters was proposed. Firstly the combination of the design of experimental method and discrete element simulation tests was used to investigate the effects of normal stiffness per unit area, shear stiffness per unit area, critical normal stress, and critical shear stress on the compressive strength and critical strain properties of the BPM. Furthermore, a fitted mathematical model between micro-mechanical parameters and macro-mechanical property parameters of iron ore was established. According to this, a bonding parameter calibration method based on Kriging surrogate model for the iron ore bonded-particle model is proposed. Finally, the micromechanical parameters of the calibrated actual iron ore bonded-particle model were verified by simulation test, which confirmed the accuracy and reliability of the proposed method and provided a new idea for the subsequent related research.