The relationship between the depth of encoding a word and its subsequent recall, either cued or noncued, was investigated in this study. In Experiment 1, Korsakoff subjects and alcoholic controls were shown a categorized word list under one of three different encoding instructions: (1) nonsemantic, that is, detecting the presence or absence of the letter “e” in each word, (2)semantic, that is, assigning words to their correct taxonomic category, and (3) no encoding instructions. Semantic encoding instructions resulted in higher recall for both diagnostic groups than the other instructions. In Experiment 2, subjects were again assigned to one of the three encoding instructions as in Experiment 1, but all groups received cues (category labels) at the time of recall. Cuing increased recall for all but the group receiving instructions to encode nonsemantically. Experiment 3 was a replication of the previous experiments. The results indicated that Korsakoff subjects were capable of encoding semantically without specific instructions to do so but were impaired in the ability to generate retrieval cues at the time of recall.