This research investigates the mechanism of how organizational factors (including organizational climate, formalization, and centralization) impact knowledge-sharing behavior by considering knowledge-sharing intention as a mediator. After conducting online surveys and offline interviews, we utilized a quantities method with the PLS-SEM tool to examine the potential findings. This study’s respondents were employees selected randomly from information technology enterprises in Vietnam; the final data set included 529 responses. The findings demonstrate that the organizational climate has a favorable link with knowledge-sharing behavior, whereas the remaining organizational factors, namely formalization and centralization, have a negative influence. Besides, this study found that knowledge-sharing intention plays a mediating role in these relationships. This research also provides some theoretical and practical implications, limitations as well as future research directions for further studies.