Abstract Aim Heart failure (HF) registries provide valuable insights into patients’ management and quality of care. However, healthcare professionals face challenges due to the administrative burden of participation in registries. This study aims to evaluate the impact of education through an engagement toolkit on HF nurse practitioners participation rate and data completeness in a national registry: the Netherlands Heart Registration- Heart Failure Registry (NHR-HF). Methods Engage-HF is an observational study (intervention at HF nurse level) with a pretest-posttest design within the participating hospitals. Between December 2022 and April 2024, 28 HF nurse practitioners from 12 hospitals will participate in a 24-week educational program using the Engage-HF engagement toolkit. The main interaction platform in this toolkit is a gamified smartphone-based educational application called Brightbird. The complete toolkit includes this educational application with weekly challenges, interactive posters, pop-ups and alert messages, and a follow-up call at week four. The primary endpoints are the NHR-HF participation rates and data completeness at 1-month and 6-months after using the toolkit. Additionally, we will analyze the experience of participants with the toolkit concerning their HF registry and ESC 2021 HF guidelines knowledge. Conclusion The ENGAGE-HF study is the first to explore the impact of education through a gamified engagement toolkit to boost participation rates in a HF registry (NHR-HF) and knowledge of the ESC 2021 HF guidelines. This innovative approach addresses challenges in healthcare registries roll out and guidelines implementation by providing a contemporary support base and time-efficient method for education.