Research Knowledge Research Articles

Are the discoveries directed to applications? Translating the status of translational research in Peshawar, Pakistan

Background: Translational research plays a pivotal role in transforming basic scientific discoveries into practical applications, such as drugs and treatments, to address community health needs. This study aims to assess the awareness and perceptions of translational research among healthcare professionals in Peshawar, Pakistan. Methods: A cross-sectional descriptive design was employed, with data collected between January and July 2023 from public and private tertiary care hospitals in Peshawar, Pakistan. The study was approved by Ethical review board of Northwest School of Medicine via letter number: IRB & EC/2022-SM/074 dated: 15 Nov 2022. A sample size of 472 healthcare professionals was determined using the OpenEpi sample size calculator. The study utilized a self-structured questionnaire covering demographic information, awareness of translational research, and knowledge of its various aspects. Data analysis was performed using SPSS version 26, employing descriptive statistics and a one-sample t-test. Results: The study included 472 participants, with a mean age of 30.8 years, comprising various healthcare roles. Gender distribution showed 62.7% males and 37.3% females. Only 25% of respondents reported familiarity with translational research, while 75% indicated a lack of awareness. Information sources varied, with conferences/seminars (16.1%) and colleagues (5.5%) being prominent. Regarding the understanding of translational research, 64.2% admitted to having no idea. Identified barriers included lack of resources (14.8%), lack of awareness (7.6%), and lack of a sense of responsibility (1.3%). A significant majority (87.3%) reported poor knowledge of translational research, while only 12.7% indicated good knowledge. Conclusion: The findings highlight a substantial lack of awareness and understanding of translational research among healthcare professionals in Pakistan.

Research Hotspots and Knowledge Framework of Digital Healthcare Service Management from the Perspective of the Silver Economy

Research Hotspots and Knowledge Framework of Digital Healthcare Service Management from the Perspective of the Silver Economy

Undergraduate health science students’ knowledge, attitudes, practices, and perceived barriers towards research at Kuwait university: a cross-sectional study

Abstract Introduction Research is the most reliable strategy to advance scientific understanding and enhance multiple healthcare services1. Integrating undergraduate health science students into research at an early stage is an important step towards improving critical thinking and problem-based solving, which in return enhances patient health outcomes2. Aim The aim of this study was to assess undergraduate health science students’ knowledge, attitudes, practices and perceived barriers towards research at Kuwait University. Methods A cross-sectional study was conducted among undergraduate health science students from the Colleges of Pharmacy, Medicine, Allied Health, Dentistry, and Public Health at Kuwait University. A self-administered online questionnaire consisting of five sections was used. The first section included questions to assess the demographic characteristics. The second section aimed to assess the knowledge of undergraduate students regarding basic research (score = low ≤3, moderate 4-5, high >5). The third section assessed attitude toward research by a five-point Likert scale (score = negative 31-75, neutral 76-110, positive 111-155). The fourth section of the questionnaire aimed to assess the perception of the barriers toward research practice (score = low 0-50, moderate 51-75, high 76-100). Finally, a section with eight questions on research practices. The questionnaire was distributed through online educational and social media platforms, such as WhatsApp and Microsoft Teams. Students from any academic year and who were enrolled as health science students at the time of the study were eligible to participate. The questionnaire was pilot tested prior to distribution. The recommended sample size was calculated using Raosoft (344 students)3. Ethical approval was received from The Health Sciences Ethical Committee, Kuwait University (reference: VDR/EC-393). Results A total of 364 undergraduate medicine, dentistry, pharmacy, allied health and public health students participated in the study. The participants were from different academic stages, ranging from first-year to seventh-year. The results showed that the students possessed moderate knowledge levels, with a median of 3 out of 8 according to the scoring system of the study. Most students had neutral attitudes (N=253; 69.5%) and moderate levels of perceived barriers (N=200; 54.9%). Medical and pharmacy students had significantly higher knowledge levels compared to the others (p<0.001; Kruskal-Wallis). The majority of students agreed that the lack of time is a barrier towards conducting research (N=237; 65.1%). Almost one half of the study participants took part in research projects (N=175; 48.1%) and a promising number of students had publications or poster presentations (N=67; 18.4%). Discussion/Conclusion The results suggest that undergraduate health science students at Kuwait University possess moderate research knowledge and have neutral attitudes towards research. Time constraints were the most frequently reported barrier to participation. While nearly half of the students participated in research projects, implementing mandatory research projects and providing research methodology workshops could significantly enhance student knowledge, attitudes, and future research engagement. A key limitation in this study is that observed relationships may not reflect long-term shifts in knowledge, attitudes, or practices. The study was also conducted in one university (Kuwait University), therefore the findings and results cannot be generalized to other undergraduate students.

Setting Tiered Management Triggers using a Values-based Approach in an Indigenous-led Cumulative Effects Management System.

Indigenous-led cumulative effects assessment and management (CEM) has emerged in recent years as a proactive and strategic approach for addressing the cumulative impacts of industrial development and other activities. CEM identifies and monitors high-priority values and stressors and develops management strategies to restore and improve the condition of those values. As Indigenous-led CEM evolves, it faces a major challenge in linking cumulative effects assessment and monitoring information to effective management actions. One promising approach to address this challenge is the use of tiered management triggers, which are a series of progressive markers associated with specified degrees of change in the condition of a value, designed to reflect increasing levels of concern about the value. These types of limits or thresholds inform decision-makers that they need to act, or act more intensively, to restore values to an acceptable state. In this paper, we present a novel method for setting tiered management triggers that was developed in an Indigenous-led CEM program. We co-developed this six-step method with the Metlakatla First Nation (located on the northwest coast of British Columbia, Canada) and applied it in a series of community workshops to select triggers for three values in the Metlakatla CEM Program: butter clams, housing, and food, social, and ceremonial activity. The method draws from participatory frameworks including structured decision-making and collaborative planning. The workshop results show that management triggers can successfully be established through a values-focused process of social choice, involving community engagement and informed by relevant scientific research and other knowledge.

Interoception and its application to paediatric occupational therapy: A scoping review.

Paediatric occupational therapists assess and provide intervention for children presenting with sensory processing challenges that impact their daily occupational performance. Interoception, the ability to sense internal body signals, is an emerging practice area, yet it remains unclear how and why paediatric clinicians are applying interoception and related concepts in practice. A scoping review was conducted to report on the current body of published literature related to interoception and its application to paediatric occupational therapy practice. A comprehensive search of 10 electronic databases and related grey literature was conducted. Title and abstract screening were completed prior to full-text review of evidence. The PRISMA-ScR Checklist and the Crowe Critical Appraisal Tool were used to support a systematic scoping review process and increase robust extraction and appraisal of data. Narrative synthesis was used to analyse and synthesise data. No consumer and community involvement. A total of 18 articles were included in this review, including original research articles (n= 8), published books (n= 4), theses/dissertations (n= 3), opinion pieces (n= 2), and one government document. Narrative synthesis analysis identified six themes: (1) occupational therapy principles relevant to interoception, (2) what is interoception?, (3) assessment of interoception, (4) clinical application of interoception, (5) clinical populations receiving interoception-based intervention, and (6) relationships between interoception and other performance components. Findings indicated that paediatric occupational therapists are integrating interoception concepts alongside occupational therapy principles to inform assessment and intervention processes. Several assessments and interventions are utilised to support children; however, evidence to strengthen use is lacking. Further, there are limited occupation-based assessments and intervention programs to address interoception deficits in children. Findings from this scoping review contribute to the emerging body of empirical evidence related to interoception and paediatric occupational therapy practice. These findings provide an informed basis for practice and research by occupational therapists in this area. Interoception allows us to feel what is going on inside our body and helps us to notice how our body might be feeling (e.g. if our stomach grumbles, we might feel hungry; if our heart is beating very fast, we might feel scared; if we are sweating, our body is feeling overheated). Some children may present with problems recognising interoceptive feelings in their bodies. Therefore, occupational therapists can help children learn about their own interoception related to their bodies. This is a new topic for therapists, and they need to know more about it so that they best help children and their families. There is not a lot of information about how to use interoception in occupational therapy practice, and we wanted to know what information already exists about interoception and occupational therapy. This review provides a summary of the current knowledge that is available and summarises it. Some information about interoception and how it relates to occupational therapy services with children was found, but more research knowledge about this topic is needed.

Organizing Scientific Knowledge from Engineering Sciences Using the Open Research Knowledge Graph: The Tailored Forming Process Chain Use Case

Organizing Scientific Knowledge from Engineering Sciences Using the Open Research Knowledge Graph: The Tailored Forming Process Chain Use Case

Robustness analysis of dynamic progressive collapse of precast concrete beam–column assemblies using dry connections under uniformly distributed load

A series of dynamic progressive collapse tests using the uniformly distributed load (UDL) was conducted, to analyze the robustness of three precast concrete (PC) beam–column assemblies using dry connections of top-and-seat angles (TSA-D), strengthened top-and-seat angles (STSA-D), and high-ductility reinforcement (DSTSA-D), under a middle column removal scenario. Finite element (FE) models were also developed to accurately simulate the collapse process. Based on the tests and FE models, comparative studies were conducted on dynamic and static collapse responses of the PC assemblies with identical configuration, loading regime, and boundary conditions. The results showed that: the horizontal reaction force developments were similar under dynamic and static collapse scenarios; under dynamic collapse scenarios, the initial stiffness of the PC assemblies increased due to the strain rate effect, while the peak vertical reaction forces under the compressive arch action (CAA) were smaller than those under static collapse scenarios, attributed to dynamic damage; under both dynamic and static collapse scenarios under UDL, the beam deformed in a downward convex curved shape, with local material deformation becoming more concentrated under dynamic collapse scenarios. An energy-based method for calculating dynamic collapse resistance was evaluated and revised: 1) the traditional method, which converts static responses from static analysis into dynamic responses was found to underestimate the resistance under small deformations due to neglecting the strain rate effect, and to overestimate ultimate resistance by ignoring dynamic damage; 2) by using dynamic vertical reaction forces instead, a more accurate prediction of the dynamic collapse resistance was achieved with a single dynamic collapse analysis. Additionally, dynamic amplification factors for the PC assemblies were calculated based on FE models and static test results providing basic knowledge in whole PC structural level research.

Bibliometric analysis of scholarly publications related to family medicine in Thailand

BackgroundFamily medicine has been recognized as a medical specialty in Thailand. However, there is a lack of information about scholarly publications. Bibliometric analysis is a valuable methodology for identifying research trends and knowledge gaps in this field. This study aims to analyze scholarly publications related to family medicine in Thailand. MethodThis bibliometric analysis was conducted based on the PubMed search in March 2023. All relevant literature related to 'family medicine' and 'Thailand' was retrieved. Performance analysis examined the publication trends from 1963 to 2023, the top 10 journals publishing relevant articles, and the number of publications by research areas. Science mapping depicted clusters of co-occurring author keywords, their relationships, and the research themes' trend over two decades. ResultsA total of 1,483 publications were retrieved. The number of publications showed an upward trend, increasing from 61 before 2000 to 359 in 2020. The Journal of the Medical Association of Thailand was the leading journal, publishing 267 articles (18.0%). Research areas were categorized into Basic Knowledge (n=211), Clinical Problem Solving (n=714), Health Service (n=256), Health System (n=254), and Medical Education (n=48). Science mapping identified six clusters based on 106 co-occurrence keywords, including public health, health services, medical issues in older adults, healthcare access, epidemiology, and others. Research themes have shifted from infectious diseases and public health to primary care and non-communicable diseases. ConclusionFuture research should focus more on implementation at a population level and healthcare system, with more investigation into geriatric care and child and maternal health.

Clinical profile of patients with acute traumatic brain injury undergoing cranial surgery in the United States: report from the 18-centre TRACK-TBI cohort study

Contemporary surgical practices for traumatic brain injury (TBI) remain unclear. We describe the clinical profile of an 18-centre US TBI cohort with cranial surgery. The prospective, observational Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (2014-2018; ClinicalTrials.gov #NCT02119182) enrolled subjects who presented to trauma centre and received head computed tomography within 24-h (h) post-TBI. We performed a secondary data analysis in subjects aged ≥17-years with hospitalisation. Clinical characteristics, surgery type/timing, hospital and six-month outcomes were reported. Of 2032 subjects (age: mean=41.4-years, range=17-89-years; male=71% female=29%), 260 underwent cranial surgery, comprising 65% decompressive craniectomy, 23% craniotomy, 12% other surgery. Subjects with surgery (vs. without surgery) presented with worse neurological injury (median Glasgow Coma Scale=6 vs. 15; midline shift ≥5mm: 48% vs. 2%; cisternal effacement: 61% vs. 4%; p<0.0001). Median time-to-craniectomy/craniotomy was 1.8h (interquartile range=1.1-5.0h), and 67% underwent intracranial pressure monitoring. Seventy-three percent of subjects with decompressive craniectomy and 58% of subjects with craniotomy had ≥3 intracranial lesion types. Decompressive craniectomy (vs. craniotomy) was associated with intracranial injury severity (median Rotterdam Score=4 vs. 3, p<0.0001), intensive care length of stay (median=13 vs. 4-days, p=0.0002), and six-month unfavourable outcome (62% vs. 30%; p=0.0001). Earlier time-to-craniectomy was associated with intracranial injury severity. In a large representative cohort of patients hospitalised with TBI, surgical decision-making and time-to-surgery aligned with intracranial injury severity. Multifocal TBIs predominated in patients with cranial surgery. These findings summarise current TBI surgical practice across US trauma centres and provide the foundation for analyses in targeted subpopulations. National Institute of Neurological Disorders and Stroke; US Department of Defense; Neurosurgery Research and Education Foundation.

Research on the design of gamified classroom teaching mode based on fuzzy conjoint analysis method

Operations research is an applied mathematics discipline aimed at providing optimal solutions for complex systems and decision-making processes. However, the theoretical aspects of operations research can often be abstract, making it challenging and potentially tedious for students with a weaker foundational background. To address this issue, game-based learning has been introduced into operations research education in recent years, demonstrating promising results. In this context, gamified learning is seen as a potential solution to enhance student motivation and classroom engagement. Although gamification has been explored in education, its application in operations research, especially within a complex mathematical domain, remains under-researched. These games transform abstract operations research theories into concrete scenarios and problems, allowing students to learn and apply operations research knowledge through interactive play. This study aims to investigate students’ perceptions and attitudes toward game-based operations research classrooms using fuzzy set joint analysis. By employing fuzzy conjoint analysis, we aim to provide a nuanced understanding of student preferences and optimize gamified teaching strategies. In the investigation process, 83 students from School D were selected as the research subjects, and a questionnaire encompassing 16 items was administered. These items covered various aspects of integrating operations research board games into the classroom, including students’ engagement, cooperation, understanding, and application of operations research knowledge during the game process. By utilizing a Likert seven-point scale to collect students’ responses to each item, the data were subsequently converted into fuzzy sets to assess students’ views on game-based operations research classrooms. The results were used to provide targeted optimization for gamified teaching. Group experimental results involving the 83 students showed that gamified teaching in operations research has a positive impact on students’ learning of the subject. This finding holds significant implications for educators and teaching practices, offering valuable insights for the design and implementation of future operations research teaching methods.

Nursing student reflections on a research internship: A reflective discussion following the Gibbs' reflective cycle

BackgroundEvidence-based practice underscores the importance of utilising research-based skills in the delivery of care. However, entry-to-practice nursing curriculums in Australia currently do not provide students with practical research opportunities. Acknowledging this gap, an Australian university initiated a two-month summer research internship that aim to expose undergraduate nursing students to clinical research under the mentorship of a nursing academic. AimTo understand the opportunities and challenges of a research internship and its contribution to developing research knowledge and skills for future nursing practice and leadership. DesignA reflective discussion following the six stages of the Gibbs' Reflective Cycle. SettingsA two-month research internship at an Australian University was held over the summer. ParticipantsTwo successful nursing students (FO and BM) who were both students in the Master of Nursing (Graduate Entry) program. MethodsFollowing the Gibbs' Reflective Cycle, a description of the internship experience was outlined, alongside feelings encountered. The opportunities and challenges of the internship are explored, evaluated, and analysed with related literature to inform an overall conclusion. To support other nursing students pursuing similar research endeavours during their professional transition, an action plan was developed. ResultsThe optional summer research internship proved to be a valuable experience for participating nursing students. FO and BM were granted co-authorship on their respective research projects, providing opportunities at international nursing and midwifery conferences and several avenues for career advancement. ConclusionsNursing research internships contribute to students' personal and professional development. This paper highlights the need for universities to provide innovative educational opportunities to students that enrich evidence-based nursing practice and inspire further opportunities.

Data-Driven Insights for a Holistic Understanding of Research Culture

Research environments (and their measurement and tracking) are becoming increasingly complex, with rapid Artificial Intelligence (AI) advancements, interdisciplinary collaboration, and global connectivity shaping the way research knowledge is created and disseminated. Within this dynamic landscape, universities hold an ever increasing collection of valuable data, which are stored within core operational systems including research information systems, research management systems or grants databases, human resource systems and course management systems. This treasure trove of information, often overlooked and underutilised, not only serves as a valuable tool in guiding strategic decisions, but also could be further used to provide a comprehensive approach to monitoring research integrity and culture. This critical reflection follows extensive conversations and debates around defining and assessing ‘research culture’. How can we possibly measure something that has, up until now, been viewed as merely a concept? How can we generate useful metrics that reflect the culture of a research institution? Our reflections will draw attention to the potential of leveraging readily accessible information to gauge and benchmark research integrity and culture practices. We discuss how regular habitual integration of these data sources enables continuous monitoring and measurement of research culture as well as the ability to assist in the assessment of interventions or initiatives designed to improve it. We reflect on how this approach ensures that University leaders have a consistent and up-to-date understanding of the research environment through which they can identify strengths, pinpoint areas for improvement, and cultivate a more robust, inclusive, and transparent research ecosystem. The current paper, through illustrative examples from one UK-based institution, explores the potential in harnessing existing data, such as collaborative trends and prevailing research practices, to gain valuable insights into the dynamics of academic research. In addition, we explore the advantages and drawbacks of using this data to develop potential metrics that can be used to recognise and reward a healthy research culture.

Epigenetics of Conjunctival Melanoma: Current Knowledge and Future Directions.

The purpose of this article is to provide a literature review of the epigenetic understanding of conjunctival melanoma (CM), with a primary focus on current gaps in knowledge and future directions in research. CM is a rare aggressive cancer that predominantly affects older adults. Local recurrences and distant metastases commonly occur in CM patients; however, their prediction and management remain challenging. Hence, there is currently an unmet need for useful biomarkers and more effective treatments to improve the clinical outcomes of these patients. Like other cancers, CM occurrence and prognosis are believed to be influenced by multiple genetic and epigenetic factors that contribute to tumor development/progression/recurrence/spread, immune evasion, and primary/acquired resistance to therapies. Epigenetic alterations may involve changes in chromatin conformation/accessibility, post-translational histone modifications or the use of histone variants, changes in DNA methylation, alterations in levels/functions of short (small) or long non-coding RNAs (ncRNAs), or RNA modifications. While recent years have witnessed a rapid increase in available epigenetic technologies and epigenetic modulation-based treatment options, which has enabled the development/implementation of various epi-drugs in the cancer field, the epigenetic understanding of CM remains limited due to a relatively small number of epigenetic studies published to date. These studies primarily investigated DNA methylation, ncRNA (e.g., miRNA or circRNA) expression, or RNA methylation. While these initial epigenetic investigations have revealed some potential biomarkers and/or therapeutic targets, they had various limitations, and their findings warrant replication in independent and larger studies/samples. In summary, an in-depth understanding of CM epigenetics remains largely incomplete but essential for advancing our molecular knowledge and improving clinical management/outcomes of this aggressive disease.

Centering equity, diversity, and inclusion in youth digital mental health: findings from a research, policy, and practice knowledge exchange workshop.

Youth mental health service organizations continue to rapidly broaden their use of virtual care and digital mental health interventions as well as leverage artificial intelligence and other technologies to inform care decisions. However, many of these digital services have failed to alleviate persistent mental health disparities among equity-seeking populations and in some instances have exacerbated them. Transdisciplinary and intersectional knowledge exchange is greatly needed to address structural barriers to digital mental health engagement, develop and evaluate interventions with historically underserved communities, and ultimately promote more accessible, useful, and equitable care. To that end, the Digital, Inclusive, Virtual, and Equitable Research Training in Mental Health Platform (DIVERT), the Maritime Strategy for Patient Oriented Research (SPOR) SUPPORT (Support for People and Patient-Oriented Research and Trials) Unit and IWK Mental Health Program invited researchers, policymakers, interprofessional mental health practitioners, trainees, computer scientists, health system administrators, community leaders and youth advocates to participate in a knowledge exchange workshop. The workshop aimed to (a) highlight local research and innovation in youth-focused digital mental health services; (b) learn more about current policy and practice issues in inclusive digital mental health for youth in Canada, (c) participate in generating action recommendations to address challenges to inclusive, diverse and equitable digital mental health services, and (d) to synthesize cross-sector feedback to inform future training curriculum, policy, strategic planning and to stimulate new lines of patient-oriented research. Eleven challenge themes emerged related to white-colonial normativity, lack of cultural humility, inaccessibility and affordability of participating in the digital world, lack of youth and community involvement, risks of too much digital time in youth's lives, and lack of scientific evidence derived from equity-deserving communities. Nine action recommendations focused on diversifying research and development funding, policy and standards, youth and community led promotion, long-term trust-building and collaboration, and needing to callout and advocate against unsafe digital services and processes. Key policy, training and practice implications are discussed.

Impact of Information System Quality on Perceived Bank Performance: Mediating Role of E-Banking Product

With the increase of information technology, the use of e-banking products recently increases tremendously in Bangladesh. So, a study is conducted to determine the direct impact of information system quality on perceived bank performance and the also indirect impact of information system quality on perceived bank performance with e-banking product mediation. Under these circumstances, the value of information system quality, perceived bank performance and e-banking product outcome are measured with five points Likert scale, with 1 being the most strongly disagreed and 5 the most strongly agreed with the statement in a close ended survey questionnaire response from 240 respondents selected by purposefully sampling method in Chattogram city, Bangladesh. In the factor analysis, principal component analysis (PCA) method is developed to classify the data into three factor and validate with Cronbach’s alpha, convergent and discriminant value from collected questionnaire response in IBM SPSS Statistics 26. Based on the above classification, structure equation model (SEM) is developed in IBM SPSS AMOS 22 to identify the mediation effect of e-banking product in the information system quality on perceived bank performance and validate with model validity. The bank authority may increase the e-banking product, which will increase the information system quality on perceived bank performance. This research knowledge may be utilized in policy making and strategy formulation to increase the perceived bank performance, which lead to more profit in future.

The need for biopsychosocial menopause care: a narrative review.

Menopause is a reproductive transition affecting half the world's population. Stigma and limited availability of evidence-based treatments that support biopsychosocial well-being mean that this life stage is often associated with challenging symptoms and reduced quality of life (QoL). The aim of this review was to examine the extent literature on psychological and mind-body interventions to manage perimenopausal and postmenopausal symptoms, and apply an interdisciplinary clinical, research, and cultural knowledge framework to guide recommendations for improving QoL and healthy aging in this population. We also aimed to understand the ideal delivery mode for such interventions. Using Scopus, Medline, and PubMed, a review of systematic reviews, guidelines, and randomized controlled trials was undertaken to examine the use of psychological and mind-body interventions to improve menopause-related QoL and symptoms, including hot flushes, depression, anxiety, fatigue, pain, and sleep; conclusions were based on an analysis of this available evidence and linked to clinical and cultural considerations. Empirical support exists for a number of psychological and mind-body approaches to support QoL and symptoms during the menopause transition. The literature also identifies the need for menopause care that is culturally responsive.An online multimodal model of menopause care is thus recommended, incorporating evidence-based treatments (eg, cognitive behavioral therapy, yoga, hypnosis) and treatment techniques (eg, mindfulness, and education including nutrition support), as well as First Nations wisdom. We also recommend financial well-being approaches to support people undergoing menopause. Integrated, multimodal approaches should be available online to remove time, location, and healthcare access barriers, and be designed with diverse consumers to ensure equity for those underserved due to region, LGBTIQ+ assigned female at birth status, and for multicultural and First Nations people.

Causes and effects of contamination of water sources due to excessive use of agrochemicals and pesticides: bibliometric analysis

ABSTRACT This article conducts a bibliometric analysis of water pollution caused by agricultural pesticides, focusing on theoretical and methodological trends. The analysis uses Scopus databases and Bibliometrix and VOSviewer software tools to analyze 2,330 documents from 2013 to 2022. The research highlights the importance of environmental, agricultural, and biological sciences in addressing water pollution. The study suggests improving pesticide use, reducing fertilizer applications, and addressing the harmful impacts of contaminated fish on human health. The restriction of glyphosate use in the European Union caused economic losses for companies, and a follow-up on glyphosate use in crop applications was proposed. The study also evaluates chemical concentrations and recommends addressing aquatic ecotoxicological risks. Future research trends include increasing water use efficiency and quality, hydrogeological studies, watersheds and land use, and climate modeling and impacts. The research is unique in addressing both research trends and knowledge gaps in water pollution research in various aspects.

Closing the Gaps in Fish Welfare: The Case for More Fundamental Work Into Physical Enrichment

ABSTRACTBillions of fishes are kept in captivity for research and food production world‐wide, with a strong impetus for maintaining high welfare standards. Accordingly, the importance of empirical research into the welfare and husbandry of captive fishes is increasingly acknowledged in both science and aquaculture, alongside growing public and governmental interest. Physical enrichment can have an important influence on welfare in of captive fishes, but many questions remain. Here, we summarise the current state of research and outline knowledge gaps in the area of physical enrichment, which is a fundamental aspect to improving welfare of captive fishes. To explore the level of research interest this area across time we conducted a series of surveys, using the number of papers published per year as a metric. These surveys highlight that work on fish welfare, while representing a relatively low proportion of fish research overall, is increasing rapidly. For species that are of aquaculture importance or used commonly as laboratory subjects, we show a positive relationship between general research interest and number of welfare‐related papers. However, for many, particularly relatively less studied, species the proportion of papers on enrichment remains low, with a slower increase compared to welfare‐related papers in general. In terms of common metrics used to quantify fish welfare, there is a reliance on growth and behaviour, with scope for inclusion and combination of a more comprehensive range of reproducible measures. We finish by highlighting recent progress, promising areas for future research and suggestions for advances in this area.

Opportunities for nursing and midwifery research in Bulgaria

Abstract Background The training of nurses and midwives today is at university level and follows established standards. The 2009 Global Standards for the basic nursing and midwifery education of the World Health Organization requires that the curricula should include basic knowledge and skills for scientific research to implement evidence-based health care. In Bulgaria, scientific research among nurses and midwives began in 2000 and has seen more serious development in the last 5 years. Methods A content analysis of normative documents was carried out, to regulate the conduct of scientific studies and the curricula for the two specialties. Results In all documents on the activities of graduate nurses and midwives, activities related to conducting scientific studies are regulated. No mandatory discipline for these competencies is included in the basic education. In Bulgaria, there is a bachelor’s and master’s program only in Health Care Management, in which sociology, statistics, and research methodology are studied. From 2000 to 2016 nurses and midwives defended doctoral dissertations in a program for medical doctors. The first doctoral program for nurses and midwives is from 2016. There are no legal norms for stimulating and provide conducting clinical research, and to ensure evidence-based practice by nurses and midwives. Conclusions The normative regulation of scientific activity among nurses and midwives in Bulgaria corresponds to international and European requirements, but the opportunities for training are limited. The responsibility of nurses and midwives to modern society is to ensure high quality in health care provided by: a. providing opportunities for clinical studies; b. implementation of evidence-based health care and practice; c. developing programs for training for research in health care. Key messages • In Bulgaria, there is a legal norms for conducting nursing research, but not for evidence-based practice. • There is a need for more opportunities to train and encourage clinical nursing research.

Training and peer-group coaching for pairs of researchers and patient representatives to support continuous two-way learning

BackgroundPatient involvement is most common during the first phases of a research project. Despite good intentions, maintaining meaningful collaborations throughout the research process doesn't seem easy. Several training programmes for researchers and patients have been developed to stimulate continuous involvement. These are mostly one-time training sessions at the start of a project, for researchers and patients separately. We aimed to co-create a prolonged side-by-side programme for pairs of patient representatives and researchers, to stimulate mutual learning from the start and throughout the research projects.MethodsWe developed a group training and peer-to-peer support programme lasting 2–3 years for 4–5 pairs of researchers and patient representatives working together on a research project. The programme took 30 h, spread over 6–8 meetings. The main goal was mutual and bi-directional learning and maintaining the collaboration throughout the research projects. From the start, the pairs were instructed to discuss communication, roles, expectations and responsibilities to prevent misunderstandings. The character of the meetings was intended to evolve from training and peer support into peer-group coaching and support for the whole group. The programme was not a fixed method, it was adjusted to the context and the needs of the participants.ResultsThus far, the programme has been applied in 5 groups, with varying health topics and types of research. Patients’ prior knowledge of research methods and researchers' experience with patient involvement varied within the groups. As a result of the side-by-side training power imbalances within pairs were reduced. All participants gained knowledge and experience in patient involvement. In subsequent group coaching sessions, they discussed issues and dilemmas on an equal footing. Most pairs found their way of working together, adapted to the wishes and capabilities of both partners. Differences between pairs were found to improve the discussions.ConclusionsWe co-created a prolonged side-by-side programme for pairs of patient representatives and researchers, to stimulate mutual learning from the start and throughout the research projects. The programme proved feasible for groups with different research types and health conditions. It fulfils an unmet need for researchers, patients and funders.