Key Partners Research Articles

Communication training program for nurses caring for patients with aphasia: a quasi-experimental study

BackgroundNurses are key communication partners for patients with aphasia. Nurses’ skills are vital for improving the patients’ environment and nursing performance. This study develops and evaluates the effectiveness of a communication training program for nurses who care for patients with aphasia.MethodsA program was developed based on the Intervention Mapping Protocol. Then, a simulation using a standardized patient with aphasia and surveys were conducted. Program effectiveness was evaluated using a quasi-experimental framework with a non-equivalent control group and pretest-posttest non-synchronized design.ResultsThe two groups exhibited statistical significant differences in health communication competence, knowledge of aphasia, patient advocacy, clinical decision-making, and compassionate competence.ConclusionThis study developed communication training for nurses who care for patients with aphasia. The effectiveness test showed that this training affected nurses’ knowledge, attitude, and skills. Clearly, communication education for nurses is important to provide comprehensive care for patients with aphasia and can enhance nursing.

Setting the balance of care for older adults at risk of hospitalization and delayed discharge: A mixed-methods research protocol.

Delayed hospital discharge is a persistent care quality issue experienced across health systems worldwide and remains a priority area to be addressed in Canada. Often associated with a decrease in services while waiting to leave the hospital, delayed discharge from hospital can lead to increased frailty, physical and cognitive decline, and caregiver burnout. Optimizing availability of and timely access to community-based health and social care are avenues that could reduce initial admissions to the hospital and length of hospital stay, and facilitate hospital discharges. This research will explore the ways in which community resources could be leveraged to potentially avoid hospitalization and delayed hospital discharge for older adults using sequential mixed-methods including co-design. To better understand the characteristics and needs of older adults, the research team will first identify sub-populations of older adults (65 years old or older) at risk of hospitalization and delayed discharge using comprehensive, longitudinal administrative health data. From these health data, risk profiles and personas will be created and then shared with key partners (e.g., older adults, caregivers, healthcare providers, healthcare decision-makers), who will be engaged to identify, leverage, and create targeted care solutions. The barriers and facilitators to the implementation of these care solutions will then be explored. Delayed hospital discharge has been a critical care quality issue across Canada for decades. The current research will provide health system leaders with an approach to better allocate services to older adults in order to avoid delayed hospital discharge and identify gaps in health and social care resources based on the characteristics, needs, and preferences of older adults, their caregivers, and providers.

Reducing Barriers to Evidence-Based Services: A High School-University Partnership to Adapt the Unified Protocol for Urban, Underserved Youth with Elevated Internalizing Symptoms

ABSTRACT Background Rates of depression and anxiety in adolescents are rising and access to effective treatment remains limited. Public schools are instrumental in reducing barriers to treatment. Objective The present study describes a community-engaged approach to the adaptation and open trial of The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A; Ehrenreich-May et al. 2018) delivered as a group-based intervention in a Chicago Public High School among predominantly low-income Black and Latine adolescents experiencing elevated depression symptoms (i.e. “Healthy Minds, Happy Lives program;” HMHL). Methods This study utilized qualitative and quantitative analyses to evaluate: (1) the systematic adaptation process that aimed to balance fidelity (to the original UP-A intervention) and flexibility (e.g. the school-based group delivery, and community partner input), (2) the initial feasibility and acceptability of the HMHL intervention by analyzing salient themes from focus groups, and (3) pre- to post-intervention changes in symptoms, in order to inform intervention refinement and methodological considerations for a pilot clinical trial. Our adaptation process utilized the Framework for Reporting Adaptations and Modifications to Evidence-based Interventions and relied on the engagement of key school-staff partners (N = 8) and student-trial participants with elevated depression symptoms (N = 16). Focus group content was coded and thematically analyzed. Outcome trends were evaluated using reliable change indices. Results Preliminary feasibility was promising, with participants attending an average of 7 out of 8 hMHL sessions and retention was excellent with 100% of participants completing the program. Additionally, most trial participants demonstrated a clinically meaningful reduction in depression symptoms and increased emotional state awareness following the intervention. Conclusions HMHL may be a feasible and acceptable intervention for increasing access to care for youth who may otherwise not have access to evidence-based services. Recommendations are provided for enhancing both the content and delivery of the intervention.

Key Information Processing Partners for Progress in Health Literacy and Practice in Karnataka

Key Information Processing Partners for Progress in Health Literacy and Practice in Karnataka

Penerapan Business Model Canvas untuk Pengembangan Bisnis TemplateKuy dalam Penyediaan Template Notion dan Spreadsheet

In the rapidly evolving digital era, effective business models are crucial for sustaining competitiveness. This research explores the application of the Business Model Canvas (BMC) to TemplateKuy, a digital platform providing Notion and Spreadsheet templates. The study aims to identify how BMC's nine components—customer segments, value propositions, channels, customer relationships, revenue streams, key resources, key activities, key partnerships, and cost structures—can be optimized for business growth and sustainability. A qualitative descriptive method was employed, involving interviews, observations, and SWOT analysis to evaluate TemplateKuy’s strategic positioning. The findings reveal that BMC helps TemplateKuy create tailored strategies that align with market demands, improve operational efficiency, and increase value for its users. However, challenges such as resource limitations and market competition persist. These results offer valuable insights for similar businesses aiming to leverage BMC for strategic planning. The study emphasizes the importance of continuous innovation and customer feedback to maintain relevance in the dynamic digital industry.

Beyond Security: The Compliance Dimension of National Security Reviews in Singapore and Taiwan

ABSTRACTGrowing concerns over Chinese investment have spurred stricter national security reviews globally, yet compliance and enforcement within these reviews remain understudied. This paper examines the enforcement mechanisms of national security review in Singapore and Taiwan, key trade partners with China. It contrasts Singapore's emphasis on rigorous ex post monitoring with Taiwan's focus on restrictive ex ante screening. To strengthen public enforcement, Singapore relies on privatized monitoring while Taiwan incorporates private enforcement. This study argues that robust state oversight through public enforcement is critical for compliance, but underscores the importance of extending enforcement beyond the initial investment stage to include post‐entry monitoring. Additionally, incorporating market intermediaries as enforcement agents presents a promising approach. This comparative analysis contributes to a richer understanding of national security review enforcement beyond traditional US‐centric framework.

Virtual relational capital for business development: a case study

Purpose The study aims to investigate virtual relational capital (VRC) to evaluate to what extent virtual relations (VR), obtained by using new technologies, support the development of firms, also considering the increasing sustainability’s needs. The study addresses the literature gap on VRC dynamics through an empirical analysis. Design/methodology/approach The investigation focuses on a single case study in the lighting industry, deepening the case of a small Italian company. The case is analyzed through the lens of the CAOS framework model by Paoloni, nurtured through direct semi-structured interviews with the entrepreneur and some managers and consultants, and data collected via web scraping. Findings VRC, obtained by the use of new technological tools, contributes to developing and fostering the innovation ecosystem in which companies need to create new skills and synergic alliances with other stakeholders. Moreover, VR can improve commercial and sales performance, stakeholder engagement and sustainability, including alignment with the circular economy and waste management principles. VRC can support smaller companies with more limited resources to connect to a broader range of actors, raising their voices with policymakers and other relevant international institutions. Originality/value The study contributes to the theoretical understanding of VRC, especially in an era in which new technologies play a fundamental role for both businesses and people. It also provides practical insights into how companies, especially smaller ones, can maximize their sustainable impact by strategically adopting virtual interactions with meaningful stakeholders like customers, key executive partners, industrial associations and policymakers.

Biological Hazards and Indicators Found in Products of Animal Origin in Cambodia from 2000 to 2022: A Systematic Review

Biological hazards in products of animal origin pose a significant threat to human health. In Cambodia, there are few comprehensive data and information on the causes of foodborne diseases or risks. To date, there has been no known published study similar to this review. This systematic review is aimed to investigate the prevalence of biological hazards and their indicators in products of animal origin from 2000 to 2022. The main objective of this study was also to contribute to strengthening Cambodia’s food control system. This review followed the established “Preferred Reporting Items for Systematic Reviews and Meta-Analyses” (PRISMA) guidelines. In total, 46 studies were retained for complete review. Most studies (n = 40) had been conducted by or with external researchers, reflecting the under-resourcing of the National Food Control System in terms of surveillance; areas outside the capital were relatively understudied, reflecting evidence found in Ethiopia and Burkina Faso. Five categories of hazards were reported with the highest number of studies on fish parasites. Marketed fish, often originating from different countries, had a higher mean value of parasite prevalence (58.85%) than wild-caught fish (16.46%). Viral pathogens in bat meat presented a potential spillover risk. Many potentially important hazards had not yet been studied or reported (e.g., Norovirus, Shigella, toxin-producing Escherichia coli, and Vibrio cholerae). The findings of our review highlighted significant urgencies for national competent authorities to enhance food hygiene practices along the production chain, tackle import control, and enforce the implementation of a traceability system, alongside more research collaboration with neighboring countries and key trading partners. It is crucial to conduct more extensive research on food safety risk analysis, focusing on the identification and understanding of various biological hazards and their associated risk factors in food.

Advisors as key partners for achieving adoption at scale: embedding “My Climate View” into agricultural advisory networks

IntroductionThis paper examines the role of agricultural advisors as key partners for scaling adoption of long-term climate information. Agri-food sectors across the world face significant challenges in responding to climate change, which intersect with broader pressures driving transitions to more climate resilient and sustainable agri-food systems. Making better climate information available to farmers is a key part of responding to these challenges, since relevant and usable climate information can help farmers to adapt to future climate conditions. The development of climate services, which seek to provide climate information to assist with decision making, has therefore increased significantly over the last decade. The Climate Services for Agriculture (CSA) program provides long-term climate projections to help the Australian agriculture sector prepare for and adapt to future climate conditions. ‘My Climate View’ is an online tool produced by CSA, which provides localised and contextualised, commodity-specific climate information, through historic weather data and multi-decadal projections of future climate, aimed at Australian famers and farm advisors. Agricultural advisors have a critical yet often underutilised role as climate information intermediaries, through assisting farmers translate climate information into action.MethodsThis paper uses CSA as a case study to examine farmer-advisor interactions as a key adoption pathway for My Climate View. We interviewed 52 farmers and 24 advisors across Australia to examine the role of advisors as key partners in helping farmers to understand climate information and explore on-farm climate adaptation options.Results and discussionInteractions between farmers and their trusted advisors are an essential part of the enabling environment required to ensure that this long-term climate information can be used at the farm scale to inform longer-term decisions about climate adaptation. We use the concept of an interaction space to investigate farmer-advisor interactions in the adoption and sustained use of My Climate View. We find that although My Climate View is not a transformational technology on its own, its ability to enable farmers and advisors to explore and discuss future climate conditions and consider climate adaptation options has the potential to support transformational changes on-farm that are needed to meet the sustainability transition pressures that climate change presents.

Driving Key Partner Engagement by Integrating Community-Engaged Principles into a Stakeholder Analysis: a Qualitative Study

Driving Key Partner Engagement by Integrating Community-Engaged Principles into a Stakeholder Analysis: a Qualitative Study

Faith-based Messaging and Materials for Colorectal Cancer Screening in the United States: Application of Boot Camp Translation within the African Methodist Episcopal Church.

The Black Church has long been an institution of refuge, mobilization, and healing in Black or African American communities. While health promotion interventions have been implemented in the Black Church, little is known about ways to incorporate faith into colorectal cancer (CRC) screening messages. Using modified boot camp translation, a community-based approach, we met with 27 members of the African Methodist Episcopal Church in Atlanta, Georgia, for in-person and virtual sessions to co-create faith-based CRC screening messages and identify channels for sharing information within the church community. Examples of messages developed included "Faith over fear" and "Honor God by taking care of your body." Identified dissemination channels included Sunday service, community events, and social media. Churches serve as key partners in delivering health information, as they are among the most trusted institutions within the Black or African American community.

Parental perspectives following the implementation of advanced hybrid closed-loop therapy in children and adolescents with type 1 diabetes and elevated glycaemia.

To identify from a parental perspective facilitators and barriers of effective implementation of advanced hybrid closed-loop (AHCL) therapy in children and adolescents with type 1 diabetes (T1D) with elevated glycaemia. Semi-structured interviews were conducted with parents of participants while in a post-trial extension phase of the CO-PILOT randomized controlled trial. The Capability, Opportunity, Motivation, Behaviour Model and Theoretical Domain Framework informed the interviews and framework analysis. Eleven parents of 9 children and adolescents were interviewed. The median age of their children and adolescents was 14.2 years (IQR 13.3-14.7) with median HbA1c 78 mmol/mol (IQR 75-86) (9.3% IQR 9-10) before starting AHCL. Facilitators of implementing AHCL therapy included the following: (1) knowledge acquired from training, (2) establishing routines and action plans, (3) remote glucose monitoring, (4) achievement of glycaemic goals through automation, (5) children/adolescents' capability to use AHCL independently, (6) improved outcomes incentivized continued AHCL, (7) optimism about sustained improvements and (8) social support from healthcare providers, school staff, peers and parents. Barriers to AHCL implementation included the following: (1) challenges with device usability, (2) need for technical support, (3) forgotten knowledge and skills, (4) non-adherence to best practices, (5) negative social influences, (6) physical and psychosocial burden and (7) negative emotions. This study provides comprehensive insights into parental perspectives of influences on implementing AHCL therapy in children and adolescents with elevated glycaemia. As parents remain key partners in diabetes care, these findings inform successful implementation of AHCL and development of future diabetes technology.

Business Development Strategy with SWOT Analysis Approach and Business Model Canvas at Wink Beauty Studio

This research aims to analyze business development strategies at Wink Beauty Studio using the SWOT Analysis and Business Model Canvas approaches. This approach aims to provide a comprehensive picture of the company's internal and external conditions and formulate the right strategy for business development. The research method used is descriptive qualitative, with data collection through in-depth interviews, observation, and documentation studies. The collected data were analyzed using a SWOT matrix to identify the strengths, weaknesses, opportunities, and threats faced by the company. The results of the SWOT analysis were then mapped into the nine elements of the Business Model Canvas, which include customer segments, value propositions, distribution channels, customer relationships, revenue streams, key resources, key activities, key partners, and cost structures. The research findings show that Wink Beauty Studio has several key strengths, such as superior service quality and customer loyalty, but also faces challenges, such as intense competition and limited resources. Development opportunities lie in the growing beauty trend and the potential of the digital market. By capitalizing on internal strengths and external opportunities, the company can develop more effective strategies to expand market reach and increase profitability. This research is expected to contribute to the management of Wink Beauty Studio in formulating the right strategic steps and become a reference for other beauty business actors in developing their businesses.

Quantifying and Visualizing Severe Thunderstorm Motion Uncertainty for Improved Decision Support

Abstract Forecasts and observations of thunderstorm motion are key components of severe thunderstorm communication and decision support for preparedness and protective behaviors, as all National Weather Service (NWS) Storm Prediction Center (SPC) convective watches and NWS warnings contain information about storm translational speed and direction of motion. The goal of this research was to quantify uncertainty in thunderstorm motion using the information contained in NWS watch and warning products. Analyzing severe thunderstorm and tornado watches and warnings from 2008 to 2020, we matched and compared forecasted storm motions given in NWS warnings with those given in SPC watches. Translational speed deviations between watches and warnings exhibited symmetry, with about one-third of warning speeds falling within ±2.5 m s−1 of forecasts. Directional deviations were also symmetrical, with one-third of warning directions within ±9° of forecasts. However, when stratified to account for translational speed, the comparisons revealed greater directional uncertainty for slower-moving storms. Temporal analysis revealed faster and rightward translations in warnings during the latter half of watch durations. Using the distributions of speed and directional deviations, we developed new visualizations to represent both mean storm motion vectors and associated uncertainty sectors, aiding interpretation of motion uncertainties. Quantifiable storm motion uncertainty also can inform estimated ranges of storm arrival times, potentially enhancing NWS communication and decision support with key partners and a range of publics for safer outcomes during severe weather events.

Bilateral Cooperation Between China and Peru Under the Belt and Road Initiative --From Strategic Layout to Future Prospects

In recent years, the bilateral relationship between China and Peru has developed rapidly, especially with the advancement of China’s Belt and Road Initiative (BRI), leading to significant progress in cooperation across areas such as economy, trade, and investment. As a major country in Latin America, Peru holds unique advantages in terms of its geopolitical location, resource reserves, and market potential, making it a key partner for China within the region. This paper explores the background of Sino-Peruvian relations, the advancement of the BRI in Latin America, and the strategic importance of Peru's Chancay Port project.

Climate Agenda in Russia: Shifting Guidelines and New Challenges

The changing of a geopolitical situation and a reorientation of Russian exports to the East were starting an adjustment the climate agenda took place in Russia, which determined the relevance of the research topic. The shift in the primary drivers of the agenda, coupled with the potential for adverse effects on the Russian real economy due to the implementation of cross-border carbon regulations within the European Union, has extended the duration of the transformational process. However, the commitment to transitioning towards a more environmentally friendly approach remains unchanged. In light of the observed change in business focus, the advancement of the climate agenda requires significant efforts from the government. Carbon neutrality and high environmental standards is economically feasible in the medium and long term. At the same time, Russia’s new key partners in the East are actively interacting with the West, which encourages them to act in line with Carbon Border Adjustment Mechanism. Therefore, these standards will eventually extend to Russian companies. The “green” transformation in domestic industries will mitigate the potential dangers of stricter carbon regulations in the East, while also providing additional competitive advantages for the Russian economy.

The Effect of ASEAN's Digital Economy Growth on China's Export Trade

Currently, the digital economy is emerging as a powerful catalyst for nations globally to enhance the caliber of their economies and to foster international trade. As one of China’s key trading partners, ASEAN holds immense potential in the growth of its digital economy, which is contributing positively to the trade interactions between China and ASEAN. Utilizing an expanded gravity model, this study investigates the influence of the digital economic progress in ASEAN countries on China’s export trade, drawing on panel data from China’s export activities with ASEAN member states between 2010 and 2022. The study shows that the degree of digital economic advancement among ASEAN member countries is diverse, with a general tendency towards improvement. The growth of the digital economy in these countries has a considerable impact on increasing the volume of China’s export trade to ASEAN. And the GDP, population, and trade and transport infrastructure of ASEAN member countries significantly contribute to the enhancement of China’s export trade.

EPCO-21. ELUCIDATING THE FUNCTIONAL RELEVANCE OF ATRX-DEFICIENCY IN H3.3-G34-MUTANT DIFFUSE HEMISPHERIC GLIOMA

Abstract Diffuse hemispheric gliomas (DHGs) account for 30% of aggressive cerebral tumors in children and young adults, exhibiting abysmal outcomes. Co-existing recurrent mutations in H3.3 histones at residue G34 (H3.3-G34R/V mutation) and concurrent inactivating mutations in TP53 and α-thalassemia/intellectual disability-X-linked gene (ATRX) implicate a coordinated molecular effort to drive oncogenesis. ATRX, a core component of the SWItch/Sucrose Non-Fermentable chromatin remodeling complex, regulates the incorporation of histone H3.3 into chromatin sites across the genome to maintain epigenome integrity. Yet, it is unclear how ATRX loss combines with H3.3-G34R/V mutations to influence cellular phenotype and dysregulate neuro-developmental programs. We propose that ATRX deficiency coordinates with key oncogenic partners by inducing oncogenic transcriptional programs and neuro-developmental pathways in DHGs. To investigate this, we employed CRISPR-editing to model H3.3-G34R followed by ATRX knockdown (ATRX-KD) in a TP53 mutant (TP53-mut) human-induced pluripotent stem cell (h-iPSC) line, developing an isogenic system to map contributions to epigenetic dysfunction made by specific molecular alterations. Upon differentiation of our h-iPSCs to neural stem cells (NSCs), we found unique transcriptional profiles associated with each genetic alteration, with upregulation of forebrain progenitor genes driven by ATRX-loss. Hierarchal clustering of normalized transcript counts revealed gene signatures from each model driving unique functional pathways, with the ATRX-KD and the triple mutant (TP53-mut, ATRX-KD, H3.3-G34R) signatures enriched for neural development pathways. Additionally, both signatures were associated with published transcriptional profiles of G34-mutant DHGs, emphasizing the disease relevance of our models. Further, time-course analysis using cerebral organoids uncovered distinct morphological changes with each alteration, with the triple mutant exhibiting impaired differentiation at later time points. These latter findings suggest that ATRX deficiency transcriptionally influences early neuronal differentiation, effects further refined by H3.3-G34 mutation. To conclude, our innovative models demonstrate the involvement of ATRX in neuro-developmental and differentiation phenotypes, illuminating underlying molecular features of aggressive DHGs.

Application of Canvas Business Model in Tourism Objects Kumpe Lake, Cilongok District, Banyumas Regency

The purpose of the study was to design a canvas business model planning idea in the future by looking at the current condition of Kumpe Lake. The analysis tool used was the canvas business model. Data was collected through interviews with informants. The identified elements of the Kumpe Lake canvas business model include:customer segmentnamely local tourists,value propositions.What is offered is Kumpe Lake tourism services and camping areas.Customer relationshipwhat is currently taking place is direct service to tourists;channels used is public mediaon instagram and Website. Key resources, panorama of Kumpe Lake; key activities,includes management of Kumpe Lake and camp area services;key partnerships,local entrepreneurs and levels of society;cost structure,program operating costs, revenue streams comes from entrance ticket revenue and camping equipment rental.

Assessing the Effectiveness of India's Free Trade Agreements (Ftas): A Comparative Analysis

This study, titled "Assessing the Effectiveness of India’s Free Trade Agreements (FTAs): A Comparative Analysis," explores the economic impact, sectoral outcomes, and implementation challenges of India’s FTAs. With an increasing number of trade agreements aimed at enhancing market access, boosting exports, and promoting economic growth, India has pursued FTAs with various countries and regional blocs, including ASEAN, Japan, and South Korea. However, these agreements have produced mixed results, with significant trade imbalances, limited export growth, and sectorial disparities, raising questions about their overall effectiveness. The study employs a comparative analysis framework, combining quantitative and qualitative methods. By analysing trade data, the study assesses changes in trade volumes, trade balances, and GDP growth post-FTA implementation. Additionally, sector-specific analyses examine the differential impact on agriculture, manufacturing, and services, revealing both gains in certain industries and challenges faced by others. Findings indicate that while FTAs have increased India's trade volume, they often disproportionately favour imports over exports, leading to trade deficits with key partners. Sectors such as IT and services have benefited from liberalized trade, while traditional industries like agriculture face competitive pressures from imports, limiting broader economic gains. Moreover, implementation challenges such as regulatory and non-tariff barriers in partner countries, low FTA utilization by Indian businesses, and limited awareness have hindered the agreements' potential benefits. Interviews with stakeholders, including policymakers and industry representatives, further highlight the need for enhanced support and strategic adjustments to maximize FTA advantages. India’s FTAs have contributed to economic integration, their effectiveness in achieving balanced trade and sustainable growth requires improvement. Recommendations include negotiating favourable terms, addressing non-tariff barriers, and increasing awareness among Indian businesses. This study’s findings provide valuable insights for policymakers to refine India’s FTA strategy, fostering more equitable and beneficial trade relationships in the future.