Kagera Region Of Tanzania Research Articles

Anti-respiratory syncytial virus and anti-herpes simplex virus activity of six Tanzanian medicinal plants with extended studies of Erythrina abyssinica stem bark

Ethnopharmacological relevanceExcept for few highly pathogenic viruses, no antiviral drug has been approved for treatment of viral infections in humans. Plant extracts, selected based on their ethno-medical use, represent an important source of compounds for the development of novel candidate antiviral drugs. This especially concerns plants with ethnomedical records on their use in treatment of viral infections. Aim of the studyTo identify and document medicinal plants used by traditional health practitioners (THPs) for treatment of respiratory infections and muco-cutaneous lesions in order to study their antiviral activity including identification of active components and elucidation of mode of antiviral activity. Materials and methodsThe ethno-medical survey was performed in the Kagera region of Tanzania. The THPs were asked for plants used for treatment of signs and symptoms of respiratory infections and watery muco-cutaneous blisters in oral and genital regions. The plants identified were successively extracted with n-hexane, ethyl acetate and water, and the extracts assayed for anti-respiratory syncytial virus (RSV), anti-herpes simplex virus 2 (HSV-2), and anti-human parainfluenza virus 2 (HPIV-2) activity in cultured cells. Antiviral components were separated by ethanol precipitation and CL-6B chromatography, and the mode of antiviral activity elucidated by the time-of-addition assay and selection for the virus variants resistant to antiviral plant extract. ResultsTHPs identified fifteen plants used for treatment of respiratory infections and muco-cutaneous blisters. The water extract, but not n-hexane or ethyl acetate extracts, of six of these plants including Erythrina abyssinica stem bark, inhibited infectivity of two glycosaminoglycan-binding viruses i.e., RSV and HSV-2 but not the sialic acid binding HPIV-2. An activity-guided separation revealed that antiviral component(s) of water extract of E. abyssinica could be precipitated with ethanol. This sample potently and selectively inhibited RSV and HSV-2 infectivity in cultured cells with IC50 values of 2.1 μg/ml (selectivity index >476) and 0.14 μg/ml (selectivity index >7143) respectively. The sample exhibited inhibitory effect on the virus attachment to and entry into the cells by directly targeting the viral particles. Indeed, 10 consecutive virus passages in HEp-2 cells in the presence of this extract selected for a resistant RSV variant lacking the attachment, viral membrane-associated, G protein due to a stop codon at amino acid residue 33 (Leu33stop). Fractionation of the E. abyssinica extract on a CL-6B column revealed that anti-RSV and HSV-2 activity correlated with carbohydrate content. The most pronounced antiviral activity was associated with a carbohydrate containing ingredient of molecular mass of <5 kDa, which may polymerize to antiviral composites of up to 410 kDa. ConclusionsAltogether, the water extract of six medicinal plants showed anti-RSV and anti-HSV-2 activities. Extended studies of the stem bark of E. abyssinica identified antiviral components that potently and selectively inhibited infectivity of free RSV and HSV-2 particles, a feature of importance in topical treatment of these infections. This observation confirms ethno-medical information concerning the use of E. abyssinica extract for treatment of respiratory infections and herpetic lesions.

Measuring the welfare effects of forests: an application of the travel cost model

AbstractIn this paper, a travel cost model was applied to the case of firewood collection to assess how the inclusion of household fixed effects and how assumptions regarding conditions in the local labor market impacted resulting welfare estimates. To assess these impacts, a unique household panel data set from Kagera, Tanzania was used. It was estimated that, under the assumption of constrained labor markets, households in the Kagera region of Tanzania are willing-to-pay, on average, $120 per year (2016 USD) for access to local forests. These estimated figures were nearly 50 per cent higher when household fixed effects were excluded and nearly 10 per cent higher under the assumption of perfect labor markets. In addition, these results support previous research showing that, in many developing countries, households' demand for firewood is inelastic and that households would be willing to spend a significant amount of their resources on forest access.

Fairtrade and Sustainability: Motivations for Fairtrade Certification among Smallholder Coffee Growers in Tanzania

Drawing on a survey of 148 Fairtrade-certified smallholder coffee farmers in the Kagera region of Tanzania, a quantitative investigation was performed on the farmers’ motivations for Fairtrade certification. A factor analysis approach was used to analyze the importance of economic, social, and environmental motivations in farmers’ decision-making on Fairtrade-labeled coffee certification. Moreover, three ordered logit models were estimated to assess the determinants of motivational behavior for Fairtrade certification among different socioeconomic groups in the survey sample. Overall, the results indicate that Fairtrade certification is predominantly economically motivated. Particularly, farmers are relatively less environmentally motivated to adopt the Fairtrade system. However, female coffee farmers are significantly more environmentally driven to adopt Fairtrade certification. Surprisingly, the results suggest that farmers’ level of education has no significant influence on their motivation for Fairtrade certification. Moreover, lower-income and smaller-scale coffee farmers are less economically and environmentally motivated for Fairtrade certification. In light of these findings, we suggest that efforts to promote Fairtrade certification among smallholder growers should be designed in ways that balance economic, social, and environmental outcomes. Furthermore, the findings call for targeted measures to strengthen Fairtrade’s commitment to empowering disadvantaged smallholder farmers, including women, to achieve sustainable development goals in the region.

Child Labor and the Arrival of Refugees: Evidence from Tanzania

The impact of hosting refugees on child labor in host countries is unclear. This paper estimates both the short and the long term consequences of hosting refugees fleeing from the genocides of Rwanda and Burundi in the Kagera region of Tanzania between 1991 and 2004. The study uses longitudinal data from the Kagera Health and Development Survey. Using the exogenous nature of refugee settlement in Kagera due to geographic and logistical reasons, we find the causal impact of hosting refugees on child labor and children's schooling outcomes. The results suggest that the impact of hosting refugees on children living in Kagera decreases child labor in the short run (between 1991 and 1994), but increases it in the longer run (1991–2004). The results are heterogeneous across gender and age. The study aims at understanding the mechanisms behind the variation in child labor outcome due to the forced migration shock exploring various channels.

Knowledge, perceptions and practices regarding brucellosis in pastoral communities of Kagera Region in Tanzania

Objective: A cross-sectional study was conducted in June 2017 to assess the knowledge, perception and practices on brucellosis by pastoralists of Kagera ecosystem in Tanzania, using qualitative methods. Materials and methods: Five focus group discussions of six participants each were conducted with livestock farmers, administration leaders, religious representatives and youth. In addition, discussions with three key informants were conducted, involving officials of livestock, wildlife and public health departments in each district. Data were analyzed using content analysis with inductive and deductive methods. Results: The study revealed low knowledge regarding brucellosis among respondents. Although participants recognized brucellosis as a zoonotic disease, they consider it of less importance. In addition, participants had low knowledge on causes, symptoms and mode of transmission of this disease. However, they perceived the interactions between humans, livestock and wildlife together with movements between borders to be potential risks for introduction of brucellosis in their communities. Moreover, their habit of drinking unpasteurized milk, the lack of protective gears during assisting animals giving birth and poor vaccination program need to be improved by community health education. Conclusion: A coordinated One Health approach is needed and further studies are suggested to reveal the status of brucellosis in Kagera ecosystem to guide its control and prevention.

\u2018Repel all biters\u2019: an enhanced collection of endophilic Anopheles gambiae and Anopheles arabiensis in CDC light-traps, from the Kagera Region of Tanzania, in the presence of a combination mosquito net impregnated with piperonyl butoxide and permethrin

BackgroundMosquito nets containing synergists designed to overcome metabolic resistance mechanisms in vectors have been developed. These may enhance excitability in the mosquitoes and affect how they respond to CDC light-traps. Investigating the behaviour of vectors of disease in relation to novel mosquito nets is, therefore, essential for the design of sampling and surveillance systems.MethodsIn an initial experiment in Muleba, Tanzania, nine bedrooms from three housing clusters were sampled. CDC light-traps were operated indoors next to occupied untreated nets (UTN), Olyset® long lasting insecticidal net (LLIN) and Olyset Plus® LLIN containing piperonyl butoxide (PBO) synergist. Nets were rotated daily between the nine rooms over nine nights. A further series of experiments using the nets on alternate nights in a single room was undertaken during the short rains. Anopheles gambiae s.l. were collected in CDC light-traps, a window-trap and Furvela tent-trap. Anopheles gambiae s.l. were identified to species by polymerase chain reaction (PCR).ResultsIn the initial experiment 97.7% of the 310 An. gambiae s.l. were An. gambiae s.s., the remainder being Anopheles arabiensis. The number of mosquitoes collected from 81 light-trap collections was greater in the presence of an Olyset [density rate ratio 1.81, 95% CI (1.22–2.67), p = 0.003] relative to an UTN. In a second experiment, in the wet season 84% of the 180 An. gambiae s.l. identified were An. arabiensis. The number of An. gambiae s.l. collected from a light-trap compared to a tent-trap was significantly higher when an Olyset Plus net was used compared to an UTN. Survival of the mosquitoes in the window trap was not reduced by the use of an Olyset Plus net in the bedroom relative to an Olyset net.ConclusionMosquitoes entering bedrooms, even those susceptible to pyrethroids, were not killed by contact with an Olyset Plus LLIN. The enhanced numbers of An. gambiae or An. arabiensis collected in light-traps when a treated net is used requires further experimentation and may be because of a heightened escape reaction on the part of the mosquito.

Local and regional spread of banana xanthomonas wilt (BXW) in space and time in Kagera, Tanzania

Banana is an important crop in the Kagera region of Tanzania. Banana xanthomonas wilt (BXW) was first reported in Kagera in 2006, and is now an important limiting factor in banana production, because all cultivars are susceptible and infected plants can fail to produce fruit. BXW is caused by Xanthomonas campestris pv. musacearum (Xcm), which is spread by farm tools, infected planting materials, and pollinating insects. Practices that address Xcm dissemination, such as mat removal, debudding and tool sterilization, have not prevented the spread of BXW in the region. Disease surveys were conducted in Kagera from 2007 to 2011 to assess BXW presence, monitor its intensity and evaluate its socioeconomic impacts. Spatiotemporal clusters of BXW were analysed with ArcGIS and sas. The relationship between BXW clusters and environmental variables was examined using bivariate correlations in spss; two modelling approaches, MaxEnt (maximum entropy) and logistic regression, were used to predict the potential distribution of BXW in Tanzania. Disease progress over time was best described with the Gompertz model. Significant clustering of BXW was observed in all years and hotspots were located in the Muleba, Karagwe, Misenyi and Bukoba rural districts. These findings suggest that BXW spreads rapidly over short distances. BXW clusters were positively correlated with rainfall and negatively with temperature and altitude. According to MaxEnt, precipitation was the main factor associated with BXW development. MaxEnt and logistic regression predicted a wide potential distribution of BXW in Tanzania because the climate in all banana‐growing regions is conducive for its establishment.

Orphanhood and mistreatment drive children to leave home – A study from early AIDS-affected Kagera region, Tanzania

The aim of this mixed-method study was to explore the trajectories of leaving home, and views and experiences among children and youth in the Kagera region in Tanzania, who have lived on the streets or been domestic workers. The main results showed that orphanhood and mistreatment were the main reasons for leaving home: few children lived with their parents before they left, and leaving home was a complex process over several years where three trajectories were identified. The children who had left home showed strong agency and competency but lived in vulnerable conditions, especially young children living on the streets.

Migration, Transfers and Child Labor

AbstractWe examine agricultural child labor in the context of emigration, transfers and the ability to hire outside labor. We start by developing a theoretical background and show how hiring labor from outside the household and transfers to the household might induce a reduction in children's working hours. Analysis using Living Standards Measurement Survey (LSMS) data on the Kagera region in Tanzania lend support to the hypothesis that both emigration and remittances reduce child labor.

Winners and Losers among a Refugee-Hosting Population

AbstractThe impact of a sudden, mass influx of forced migrants on the hosting economy is understudied and not well understood. Using a household panel data set for the Kagera region in Tanzania, we test the impact of the mass refugee presence on the welfare of the local population. Our identification strategy exploits variations in the timing of arrival as well as the spatial distribution of Rwandese and Burundi refugees. We find a positive and aggregate effect, but households are affected differently depending on their main initial occupation.

Non-communicable diseases in antiretroviral therapy recipients in Kagera Tanzania: a cross-sectional study

IntroductionThe aim of this study was to describe the extent of self-reported non-communicable diseases (NCDs) among highly active antiretroviral therapy (HAART) recipients in Kagera region in Tanzania and their effect on health-related quality of life (HRQOL). This study was conducted 2 years after HAART administration was started in Kagera region.MethodsThe SF-36 questionnaire was used to collect the HRQOL data of 329 HAART recipients. Questions on the NCDs, socio-demographic characteristics and treatment information were validated and added to the SF-36. Bivariate analyses involving socio-demographic characteristics and SF-36 scores of the recipients were performed. Multiple logistic regression was employed to compute adjusted odds ratios for different explanatory variables on physical functioning and mental health scores.ResultsRespondents who reported having 1 or more NCDs were 57.8% of all the respondents. Arthritis was the commonest NCD (57.8%). Respondents with the NCDs were more likely to have HRQOL scores below the mean of the general Tanzanian population. The population attributable fraction (PAF) for the NCDs on physical functioning was 0.28 and on mental health was 0.22.ConclusionSelf-reported NCDs were prevalent among the HAART recipients in Kagera region. They accounted for 28% of the physical functioning scores and 22% of the mental health scores that were below the mean of the general Tanzanian population. Therefore, the integration of NCD care is important in the management of HIV/AIDS.

Measuring Catch-Up Growth in Malnourished Populations

Chronic malnutrition during early childhood hinders growth and causes children to fall into a lower growth trajectory. In order to recover, children need to experience growth rates that are above the expected rate for their age. Several studies have analysed the extent of such catch-up growth by regressing adult height on early childhood height. In this paper, I show that these studies confuse catch-up growth with within-population convergence and are further plagued by a well-known statistical fallacy of regression-to-the-mean. This calls for a re-evaluation of the existing evidence. In the empirical part of the paper, I use data from the Philippines and the Kagera region in Tanzania to study catch-up growth. I find limited recovery in the Philippines cohort. In Kagera, almost 75 per cent of the children experience catch-up growth. The mean height-for-age z-score improves from -1.87 in early childhood to -1.20 by adulthood. Graphical analysis reveals that this catch-up growth takes place in puberty.

High Initial HIV/AIDS-Related Mortality and -Its Predictors among Patients on Antiretroviral Therapy in the Kagera Region of Tanzania: A Five-Year Retrospective Cohort Study.

We examined mortality rates and its predictors from a five years retrospective cohort data of HIV/AIDs patients attending care and treatment clinic in Biharamulo Tanzania. Cox regression analysis was used to identify predictors of mortality. Of the 546 patient records retrieved, the mean age was 37 years with median CD4 count of 156 cells. The mortality rate was 4.32/100 person years at risk with males having three times higher mortality compared to females. Starting Antiretroviral treatment with advanced disease state, body weight below 45 kegs, WHO stage 4 disease, and CD4 cells below 50 were main predictors of mortality. Promoting early voluntary counselling and testing should be given a priority to facilitate timely start of treatment.

A woman can sing and dance but cannot dance with high leaps: musical performance of the Haya of Bukoba, Tanzania

In the area covering the present day Muleba and Bukoba Urban and Bukoba Rural Districts, as is the case in other areas where Buhaya culture is predominant in the Kageraregion in Tanzania, musical performances - singing, dancing, and playing of musical instruments - are integral parts of everyday life. As is the case in many African societies, among the Haya musical performances are inseparable from the daily events and the social, political and cultural life of the community. Traditionally, events such as marriage, funerals, worship, installation, praise, and exaltation of kings (omukama), celebratory war dances (omutoro) and heroic recitations or self-praise recitations (ebyebugo), healing practices such as cleansing and chasing away evil spirits, and all occasions calling for celebration produced performances. In the contemporary Haya world, some such events (for example, war dances and installation of traditional leaders) have ceased, but the musical performances have been re-contextualized for religious, social, health and political purposes.

Exploring the role of cognitive and structural forms of social capital in HIV/AIDS trends in the Kagera region of Tanzania – a grounded theory study

The article presents a synthesis of data from three village case studies focusing on how structural and cognitive social capital may have influenced the progression of the HIV epidemic in the Kagera region of Tanzania. Grounded theory was used to develop a theoretical model describing the possible links between structural and cognitive social capital and the impact on sexual health behaviours. Focus group discussions and key informant interviews were carried out to represent the range of experiences of existing social capital. Both structural and cognitive social capital were active avenues for community members to come together, empower each other, and develop norms, values, trust and reciprocal relations. This empowerment created an enabling environment in which members could adopt protective behaviours against HIV infection. On the one hand, we observed that involvement in formal and informal organisations resulted in a reduction of numbers of sexual partners, led people to demand abstinence from sexual relations until marriage, caused fewer opportunities for casual sex, and gave individuals the agency to demand the use of condoms. On the other hand, strict membership rules and regulations excluded some members, particularly excessive alcohol drinkers and debtors, from becoming members of the social groups, which increased their vulnerability in terms of exposure to HIV. Social gatherings (especially those organised during the night) were also found to increase youths’ risk of HIV infection through instances of unsafe sex. We conclude that even though social capital may at times have negative effects on individuals’ HIV-prevention efforts, this study provides initial evidence that social capital is largely protective through empowering vulnerable groups such as women and the poor to protect against HIV infection and by promoting protective sexual behaviours.

Migration, Transfers and Child Labor

We examine agricultural child labor in the context of emigration, transfers, and the ability to hire outside labor. We start by developing a theoretical background based on Basu and Van, (1998), Basu, (1999, 2000) and Epstein and Kahana (2008) and show how hiring labor from outside the household and transfers to the household might induce a reduction in children’s working hours. Analysis using Living Standards Measurement Survey (LSMS) data on the Kagera region in Tanzania lend support to the hypothesis that both emigration and remittances reduce child labor.

Social capital and the decline in HIV transmission – A case study in three villages in the Kagera region of Tanzania

We present data from an exploratory case study characterising the social capital in three case villages situated in areas of varying HIV prevalence in the Kagera region of Tanzania. Focus group discussions and key informant interviews revealed a range of experiences by community members, leaders of organisations and social groups. We found that the formation of social groups during the early 1990s was partly a result of poverty and the many deaths caused by AIDS. They built on a tradition to support those in need and provided social and economic support to members by providing loans. Their strict rules of conduct helped to create new norms, values and trust, important for HIV prevention. Members of different networks ultimately became role models for healthy protective behaviour. Formal organisations also worked together with social groups to facilitate networking and to provide avenues for exchange of information. We conclude that social capital contributed in changing HIV related risk behaviour that supported a decline of HIV infection in the high prevalence zone and maintained a low prevalence in the other zones.

Moving out of Poverty in Tanzania: Evidence from Kagera

This paper uses linked qualitative and quantitative data to explore the growth trajectories of matched households in the Kagera region of Tanzania, finding that agriculture and trade provided the two main routes out of poverty. The interplay between initial conditions, shocks, networks and experiences of life beyond their village determine whether a person moves out of poverty in the following decade.

Preschool Nutrition and Subsequent Schooling Attainment: Longitudinal Evidence from Tanzania

Abstract This study analyzes how childhood health determines future academic performance in the Kagera region in Tanzania. Academic outcomes considered are years of education and delay in enrollment, and the measure of childhood health is height (relative to the median). The repercussions of malnutrition in childhood on subsequent learning and school performance are analyzed by using a unique longitudinal data set. Results indicate the degree to which malnutrition leads to reduced lifetime earning capacity due to both delays in schooling and declines in total schooling.

Field notes on administering shock modules

AbstractIncreasingly panel household questionnaires in developing countries will include a shock module to collect information on past shocks experienced by the household. Still, very little information is available on what one needs to take into consideration when designing these modules. This note discusses field experiences gained from piloting a shock module in the Kagera Region of Tanzania. Pilots were conducted with two fundamentally different designs of shock modules. We discuss the advantages and disadvantages of using a structural form shock module, which walks the respondent through a list of shocks, and compare it to using a reduced form one, which probes for welfare changes over time. Copyright © 2008 John Wiley &amp; Sons, Ltd.