Background and purpose: This literature review objective is to appraise the outcome of the Impact of blood flow restriction training as a supplemental rehabilitation technique for chronic ankle instability patients. Methods: This literature review constitutes the articles which were published in 2017-2023. The evidence search was performed on Google Scholar, PubMed, Web of Science, Pedro database and Cochrane Library. Results: According to 20 studies included in our review shows that BFR training has been useful in increasing muscle strength and hypertrophy; there was increased production of ATP in muscle mitochondria & Increased VO2 max along with other neuro-myogenic factors, which indicate increased adaptations post-injury. Conclusion: This literature review, according to selective studies, demonstrates that the addition of BFR in conventional rehabilitation resulted in increased muscle adaptations like strength and hypertrophy, along with increased balance and tissue remodelling and decreased pain perception, which could be beneficial in the treatment of ankle dysfunction. Keywords: Blood Flow Restriction Training, Occlusion Training, KAATSU Training, Chronic Ankle Instability, Muscle Adaptations.
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