Joint Doctorate Research Articles

SISTEM INFORMASI REKAM MEDIS PASIEN PADA KLINIK PAKTEK DOKTER BERSAMA BERBASIS WEB

The Joint Doctor's Practice Clinic is a practice that serves the treatment of various diseases. In the data processing process using handwriting, so that there are problems in processing medical record data, namely to get patient information, visit information, diagnostic information and doctor information, it still takes a relatively long time because they have to search for information manually in the medical record book. The purpose of this study is to analyze the current system, in order to overcome the problems faced at the Joint Doctor's Practice Clinic, by designing a Patient Medical Record Information System at the Joint Doctor's Practice Clinic. Research Framework that will be carried out in solving the problems discussed, namely, identifying problems, data collection, data analysis, system design, implementation, system testing to the maintenance phase. The system development method uses a waterfall model, the implementation of this research uses the PHP programming language and MySQL DBMS. To produce a data processing application that is expected to facilitate the processing of medical record data and the manufacture of medical record reports

Importance and influence of sensorimotor exercises of the knee joint muscles on body stability

Introduction: The concept of prioprioception, known as a conceived solution, which is formed from prioprioceptors that reach the spinal cord, may give rise to reflex reactions. In all changes to a change that affect the behavior of the data, it should be noted that it is recorded, and that it is appropriate and appropriate. What is dependent reaction to change, reaction to change reaction to change, behavior change, change in orientation is a change? Aim of the study: The aim of the study is to assess the effect of the sensorimotor muscles of the knee joint on the muscles. The improvement point was assessed. Material and methods: 20 patients tested fabrics. Among women and 9 men. In order to improve the company's condition, streamlining the technique of the technique on the Easy Tech balancing platform. A fitting with a radius of 20 cm was used in the tests. You repair the research group on the platform twice. The first test was performed immediately after the warm-up, the next test was performed by the knee joint doctor after the running and independent education. Effect on the improvement of treatment outcomes In tests shown to cut sex for performance. Reaching for the improvement of health and improvement of the client's condition. Conclusions: The technology used, a one-time method of sensorimotor training, to improve the results of users of knee injuries. One-time sensorimotor training, the doctor of the knee joint did not show a differential calculation of statistical statistics in relation to the significance of BMI. Note a weak positive correlation, not statistically significant, showing that the heavier person improved the results.

POLYTHEA – The opportunities and challenges of doctoral training networks

Photodynamic therapy (PDT) is a multi-component therapy which relies on the delivery of a photosensitizer drug and light in the presence of oxygen to mediate a therapeutic anti-cancer or anti-microbial effect. As a multi-component therapy, a multidisciplinary research approach is required to achieve success with the application of PDT. The POLYTHEA network, a project funded under the Marie Skołodowska-Curie Actions (MSCA) of Horizon 2020 (H2020) program, provided an opportunity to build a collaboration of laboratories across Europe with the necessary expertise required for the different facets of PDT. In the process, ten early-stage researchers (ESRs) were trained with the aim of achieving European Joint Doctorate degrees. The project managed to fulfill goals of collaborative research, transferable skills training, and public outreach, despite the occurrence of the Covid-19 pandemic. The benefits of this type of MSCA funding for the main participants, students and supervisors, are highly relevant to their career but are not free from challenges. With the POLYTHEA project soon ending, a reflection of the most positive and negative aspects of the project from its inception is opportune.

Away with oppressed methodology! Reflections on an experiment in Law & Development education

Ten years ago, six institutions came together to establish a joint doctoral programme. The shared motivations behind this project were to improve the quality of doctoral research that we encountered and to create a space for qualitative research within our law schools. We called the project the ‘European Joint Doctorate in Law and Development’ (EDOLAD). A key element of the programme was to be a core, and therefore compulsory, curriculum that all researchers were to follow. For most of the scholars involved in the project, L&D was a useful label that allowed us to bridge our different interests and to create shared ground. For some, though, the core curriculum also provided an opportunity to define what we thought L&D education or legal research should be. What emerged was a focus on critical methodology. This paper explores this by reflecting on what we had hoped to achieve with the core curriculum and draws on EDOLAD researchers’ experiences to determine what impact our efforts at creating an L&D-focused education may have had. What our reflections here suggest, in part, is the difficulty of creating a coherent, field-building, programme of education in a multi-university collaboration in which resources are unevenly distributed; but also, more interestingly, that L&D as a concept - at least as we imagined it - seems to struggle to provide a scholarly identity for critical researchers.

Transitions to Long-Term Residential Care Settings

During their life course, many older adults encounter a transition between care settings, for example, a permanent move into long-term residential care. This care transition is a complex and often fragmented process, which is associated with an increased risk of negative health outcomes, rehospitalisation, and even mortality. Therefore, care transitions should be avoided where possible and the process for necessary transitions should be optimised to ensure continuity of care. Transitional care is therefore a key research topic. The TRANS-SENIOR European Joint Doctorate (EJD) network builds capacity for tackling a major challenge facing European long-term care systems: the need to improve care for an increasing number of care-dependent older adults by avoiding unnecessary transitions and optimising necessary care transitions. During this symposium, four presenters from the Netherlands and Switzerland will present different aspects of transitions into long-term residential care. The first speaker presents the results of a co-creation approach in developing an intervention aimed at preventing unnecessary care transitions. The second speaker presents an overview of interventions aiming to improve a transition from home to a nursing home, highlighting the clear mismatch between theory and practice. The third speaker presents the impact of the COVID-19 pandemic on transitions into long-term residential care using an ethnographic study in a long-term residential care facility in Switzerland. The final speaker discusses the results of a recent Delphi study on key factors influencing implementing innovations in transitional care. The discussant will relate previous findings on transitional care with a U.S. perspective.

UrbanHIST: a multidisciplinary research and training programme on the history of European urbanism in the twentieth century

ABSTRACT This paper introduces the Planning Perspectives readership to urbanHIST, a current Horizon 2020 European Joint Doctorate programme that focuses on the history of European urbanism in the twentieth century. Its concept is based on the inherent multidisciplinary approach of the research field and the ambition to gain a pan-European perspective on planning history. The paper delineates the underlying general research trends and the current responses of urbanHIST. Finally, it connects the programme's thematic orientation with both, its external contributions and its internal key activities that might bridge the gap between the protected environment of a PhD programme with the reality of academic life.

SMART Research: Toward Interdisciplinary River Science in Europe

Interdisciplinary science is rapidly advancing to address complex human-environment interactions. River science aims to provide the methods and knowledge required to sustainably manage some of the planet’s most important and vulnerable ecosystems; and there is a clear need for river managers and scientists to be trained within an interdisciplinary approach. However, despite the science community’s recognition of the importance of interdisciplinary training, there are few studies examining interdisciplinary graduate programmes, especially in science and engineering. Here we assess and reflect on the contribution of a 9-year European doctoral programme in river science: ‘Science for MAnagement of Rivers and their Tidal Systems’ Erasmus Mundus Joint Doctorate (SMART EMJD). The programme trained a new generation of 36 early career scientists under the supervision of 34 international experts from different disciplinary and interdisciplinary research fields focusing on river systems, aiming to transcend the boundaries between disciplines and between science and management. We analysed the three core facets of the SMART programme, namely: (1) interdisciplinarity, (2) internationalism, and (3) management-oriented science. We reviewed the contents of doctoral theses and publications and synthesised the outcomes of two questionnaire surveys conducted with doctoral candidates and supervisors. A high percentage of the scientific outputs (80%) were interdisciplinary. There was evidence of active collaboration between different teams of doctoral candidates and supervisors, in terms of joint publications (5 papers out of the 69 analysed) but this was understandably quite limited given the other demands of the programme. We found evidence to contradict the perception that interdisciplinarity is a barrier to career success as employment rates were high (97%) and achieved very soon after the defence, both in academia (50%) and the private/public sector (50%) with a strong international dimension. Despite management-oriented research being a limited (9%) portion of the ensemble of theses, employment in management was higher (22%). The SMART programme also increased the network of international collaborations for doctoral candidates and supervisors. Reflections on doctoral training programmes like SMART contribute to debates around research training and the career opportunities of interdisciplinary scientists.

Asthma in Pregnancy: Pathophysiology, Diagnosis, Whole-Course Management, and Medication Safety.

Asthma in pregnancy is a health issue of great concern. Physiological changes and drug compliance during pregnancy can affect asthma control in varying degrees, and the control level of asthma and the side effects of asthma medications are closely related to the adverse perinatal outcomes of mother and fetus. This article provides an update on the available literature regarding the alleviating or aggravating mechanism of asthma in pregnancy, diagnosis, disease assessment, and systematic management, to provide a new guidance for physician, obstetric joint doctor, and health care practitioner.

Initial steps in reconstruction of the human ovary: survival of pre-antral stage follicles in a decellularized human ovarian scaffold.

Can a reconstructed ovary using decellularized human ovarian tissue (DCT) support survival of pre-antral stage follicles? We have demonstrated an effective protocol for decellularization of human ovarian tissues and successful recellularization with isolated human ovarian cells and pre-antral follicles. Survivors of leukemia or ovarian cancer run a risk of reintroducing malignancy when cryopreserved ovarian tissue is transplanted to restore fertility. A reconstructed ovary free of malignant cells could provide a safe alternative. Decellularization of ovarian tissue removes all cells from the extracellular matrix (ECM) including possible malignancies and leaves behind a physiological scaffold. The ECM offers the complex milieu that facilitates the necessary interaction between ovarian follicles and their surroundings to ensure their growth and development. Previous studies have shown that decellularized bovine ovarian scaffolds supported murine follicle growth and restoration of ovarian function in ovariectomized mice. Optimizing a decellularization protocol for human ovarian tissues and testing biofunctionality of the decellularized scaffolds in vitro and in vivo by reseeding with both murine and human pre-antral follicles and ovarian cells. Donated human ovarian tissue and isolated pre-antral follicles were obtained from women undergoing ovarian tissue cryopreservation for fertility preservation. Ovarian cortical and medullary tissues were decellularized using 0.1% sodium dodecyl sulfate (SDS) for 3, 6, 18 and 24hours followed by 24hours of 1mg/mL DNase treatment and washing. Decellularization of ovarian tissues and preservation of ECM were characterized by morphological evaluation using Periodic Acid-Schiff (PAS) staining, DNA quantification, histochemical quantification of collagen content and immunofluorescence analysis for collagen IA, laminin, fibronectin and DNA. Human ovarian stromal cells and isolated human pre-antral follicles were reseeded on the DCT and cultured in vitro. Isolated murine (N= 241) and human (N= 20) pre-antral follicles were reseeded on decellularized scaffolds and grafted subcutaneously to immunodeficient mice for 3 weeks. Incubation in 0.1% SDS for 18-24hours adequately decellularized both human ovarian medullary and cortical tissue by eliminating all cells and leaving the ECM intact. DNA content in DCT was decreased by >90% compared to native tissue samples. Histological examination using PAS staining confirmed that the cortical and medullary tissues were completely decellularized, and no visible nuclear material was found within the decellularized sections. DCT also stained positive for collagen I and collagen quantities in DCT constituted 88-98% of the individual baselines for native samples. Human ovarian stroma cells were able to recellularize the DCT and isolated human pre-antral follicles remained viable in co-culture. Xenotransplantation of DCT reseeded with human or murine pre-antral follicles showed, that the DCT was able to support survival of human follicles and growth of murine follicles, of which 39% grew to antral stages. The follicular recovery rates after three weeks grafting were low but similar for both human (25%) and murine follicles (21%). N/A. Further studies are needed to increase recovery and survival of the reseeded follicles. Longer grafting periods should be evaluated to determine the developmental potential of human follicles. Survival of the follicles might be impaired by the lack of stroma cells. This is the first time that isolated human follicles have survived in a decellularized human scaffold. Therefore, this proof-of-concept could be a potential new strategy to eliminate the risk of malignant cell re-occurrence in former cancer patients having cryopreserved ovarian tissue transplanted for fertility restoration. This study is part of the ReproUnion collaborative study, co-financed by the European Union, Interreg V ÖKS. Furthermore, Project ITN REP-BIOTECH 675526 funded by the European Union, European Joint Doctorate in Biology and Technology of the Reproductive Health, the Research Pools of Rigshospitalet, the Danish Cancer Foundation and Dagmar Marshalls Foundation are thanked for having funded this study. The funders had no role in the study design, data collection and interpretation, or in the decision to submit the work for publication.

A Hitchhiker's guide to Mediterranean marina travel for alien species

This work was funded by a PhD Scholarship awarded to Aylin Ulman from the MARES- Erasmus Mundus Joint Doctoral Fellowship Program in Marine Ecosystem Health and Conservation. MARES is a Joint Doctorate programme selected under Erasmus Mundus coordinated by Ghent University (FPA 2011-0016). A COST Action #1209 grant was provided to Aylin Ulman to visit the University of Alicante, Spain.

Handling the loss of innocence: first-time exchange of writing and feedback in doctoral supervision

ABSTRACTThe first time of many significant encounters is the most intense, raising awkwardness, anxiety and hope. This article presents data from doctoral students (n = 80) who described the first time that they submitted writing to their supervisor and received feedback. The first writing/feedback exchange is an initiation into the cultures of academia. Student accounts captured the intensity of the initiation for students, excitement or dread on submitting writing, with increased emotional reaction when going through the feedback process, that liminal first time. Close focus on the first-time writing feedback exchange makes a contribution to the literature on the social interactions of doctoral writing. Data backs our argument that students and supervisors need to carefully manage the first-time exchange of writing. Our findings are analysed thematically and through an autoethnographic lens of the lead author, who was both a research assistant for the research survey and an international doctoral student experiencing the same processes in his cross-disciplinary joint doctorate. We draw on conceptual threshold-crossing theories established in regard to doctoral learning.

Prognostic variables for successful lexical retrieval of treated and untreated verbs vary greatly suggesting that different cognitive processes might underlie the production of treated and untreated verbs

This review provides a summary and appraisal commentary on the treatment review by de Aguiar, V., Bastiaanse, R., & Miceli, G. (2016). Improving production of treated and untreated verbs in aphasia: A meta-analysis. Frontiers in Human Neuroscience, 10:468. doi: 10.3389/fnhum.2016.00468Source of funding and declaration of interests: Funding was provided by the Provincia Autonoma di Trento and Fondazione CaRiTRO and Erasmus Mundus Joint Doctorate IDEALAB. No conflicts of interests were declared.

Problems of (Self-) education Substantiated by Scientific Research

Problems of (Self-) education Substantiated by Scientific Research

Spatial patterns of carbon, biodiversity, deforestation threat, and REDD+ projects in Indonesia.

There are concerns that Reduced Emissions from Deforestation and forest Degradation (REDD+) may fail to deliver potential biodiversity cobenefits if it is focused on high carbon areas. We explored the spatial overlaps between carbon stocks, biodiversity, projected deforestation threats, and the location of REDD+ projects in Indonesia, a tropical country at the forefront of REDD+ development. For biodiversity, we assembled data on the distribution of terrestrial vertebrates (ranges of amphibians, mammals, birds, reptiles) and plants (species distribution models for 8 families). We then investigated congruence between different measures of biodiversity richness and carbon stocks at the national and subnational scales. Finally, we mapped active REDD+ projects and investigated the carbon density and potential biodiversity richness and modeled deforestation pressures within these forests relative to protected areas and unprotected forests. There was little internal overlap among the different hotspots (richest 10% of cells) of species richness. There was also no consistent spatial congruence between carbon stocks and the biodiversity measures: a weak negative correlation at the national scale masked highly variable and nonlinear relationships island by island. Current REDD+ projects were preferentially located in areas with higher total species richness and threatened species richness but lower carbon densities than protected areas and unprotected forests. Although a quarter of the total area of these REDD+ projects is under relatively high deforestation pressure, the majority of the REDD+ area is not. In Indonesia at least, first-generation REDD+ projects are located where they are likely to deliver biodiversity benefits. However, if REDD+ is to deliver additional gains for climate and biodiversity, projects will need to focus on forests with the highest threat to deforestation, which will have cost implications for future REDD+ implementation.Los Patrones Espaciales del Carbono, la Biodiversidad, la Amenaza de Deforestación y los Proyectos REDD+ en IndonesiaResumenActualmente hay preocupación por que las Emisiones Reducidas de la Deforestación y Degradación del Bosque (REDD+, en inglés) puedan fallar en la entrega de co–beneficios potenciales de la biodiversidad si se enfocan en áreas de alto carbono. Exploramos los traslapes espaciales entre los stocks de carbono, la biodiversidad, las amenazas proyectadas de deforestación y la ubicación de proyectos REDD+ en Indonesia, un país tropical a la vanguardia del desarrollo REDD+. Para la biodiversidad, reunimos datos sobre la distribución de vertebrados terrestres (hábitats de anfibios, mamíferos, aves y reptiles) y plantas (modelos de distribución de especies para ocho familia). Después investigamos la congruencia entre las diferentes medidas de la riqueza de la biodiversidad y los stocks de carbono en la escala nacional y sub–nacional. Finalmente mapeamos proyectos REDD+ activos e investigamos la densidad de carbono y la riqueza potencial de la biodiversidad y modelamos presiones de deforestación dentro de estos bosques en relación con áreas protegidas y no protegidas. Hubo poco traslape interno entre los diferentes hotspots (el 10% más rico de las celdas) de riqueza de especies. Tampoco hubo congruencia espacial consecuente entre los stocks de carbono y las medidas de la biodiversidad: una correlación negativa débil en la escala nacional enmascaró las relaciones altamente variables y no-lineales isla por isla. Los proyectos REDD+ actuales estuvieron ubicados preferencialmente en áreas con una riqueza total de especies y con una riqueza de especies amenazadas más altas pero con densidades de carbono más bajas que en las áreas protegidas y los bosques sin protección. Aunque un cuarto del área total de estos proyectos REDD+ está bajo una presión de deforestación relativamente alta, la mayoría del área REDD+ no lo está. Por lo menos en Indonesia, los proyectos REDD+ de primera generación están ubicados en donde tengan probabilidad de entregar beneficios para la biodiversidad. Sin embargo, si se espera que REDD+ entregue beneficios adicionales para el clima y la biodiversidad, los proyectos necesitarán enfocarse en los bosques con la mayor amenaza de deforestación, lo que tendrá implicaciones de costo para la implementación futura de REDD+.

Electrophysiology of Sentence Processing in Aphasia: Prosodic Cues and Thematic Fit

Electrophysiology of Sentence Processing in Aphasia: Prosodic Cues and Thematic Fit

The Impact of Similarity-Based Interference in Processing Wh-Questions in Aphasia

The Impact of Similarity-Based Interference in Processing Wh-Questions in Aphasia

Managing Your Angina Symptoms With Nitroglycerin

You have been diagnosed with angina pectoris, commonly referred to as angina. This condition may be associated with discomfort in the chest or adjacent areas. Other symptoms of angina may include shortness of breath, fatigue, or nausea. The symptoms you feel are usually the result of a temporary lack of blood flow to your heart muscle, often caused by a blockage in the blood vessels that feed your heart. It is especially noticeable when there is an increased demand on your heart to pump blood such as during exercise or periods of emotional stress. There are 2 types of angina. If you have discomfort that usually arises on increased physical activity or stress, it is called stable angina. If your discomfort occurs with minimal activity or at rest or is increasing in frequency or intensity, it is called unstable angina. Angina is common in patients with coronary artery disease (CAD; blocked heart arteries usually caused by cholesterol and other risk factors such as high blood pressure, diabetes mellitus, and cigarette smoking) and occurs in both men and women across all age groups. Generally, patients with chronic stable angina have reduced quality of life and are less likely to participate in regular physical activity programs. Nitroglycerin, also referred to as “nitro,” has been used with success for more than a century to treat angina. Nitroglycerin is a useful medication to help patients with CAD “reintroduce” physical activity into their lives. Nitroglycerin may alleviate the discomfort of both stable and unstable angina. Most patients with CAD can reduce their risk of future heart problems if they make changes to their lives that help improve their health. One of the important lifestyle changes is participating in regular exercise. Research shows that routine exercise not only improves quality of life but also reduces the …

Waking Up to the Risks of Online Direct-to-Consumer Advertising of Sleep Apnea Screening Tests

Waking Up to the Risks of Online Direct-to-Consumer Advertising of Sleep Apnea Screening Tests

Felon Disenfranchisement and the Fight for Universal Suffrage

Journal Article Felon Disenfranchisement and the Fight for Universal Suffrage Get access Jonah A. Siegel, MSW Jonah A. Siegel, MSW student Joint Doctoral Program in social work and sociology, University of Michigan, Ann Arbor Address correspondence to the author at University of Michigan, Weill Hall, Room 5115, 735 South State Street, Ann Arbor, MI 48109; e-mail: siegelja@umich.edu Search for other works by this author on: Oxford Academic PubMed Google Scholar Social Work, Volume 56, Issue 1, January 2011, Pages 89–91, https://doi.org/10.1093/sw/56.1.89 Published: 01 January 2011 Article history Received: 10 September 2008 Accepted: 23 January 2009 Published: 01 January 2011

Neuron versus Time Clustering in the Identification of Cell Assemblies

Event Abstract Back to Event Neuron versus Time Clustering in the Identification of Cell Assemblies Carlos Toledo-Suárez1, 2, 3*, Man Yi Yim1, 4, Arvind Kumar1, 4 and Abigail Morrison1, 2 1 University of Freiburg, Germany 2 University of Freiburg, Faculty of Biology, Germany 3 School of Computer Science and Communication, KTH, Computational Biology, Sweden 4 University of Freiburg, Faculty of Biology, Germany A major challenge in the analysis of neural activity data when considering spikes as the main information carrying unit is the detection of sets of neurons which act as functional groups. Such neuronal cell assemblies can be identified by clustering the spectrum of zero-lag cross-correlation between all pairs of neurons in a network or by dimensionality reduction of the similarity matrix of the spike trains. Here we investigate how the identification of cell assemblies is dependent on the methodology chosen. We construct a self similar network of inhibitory adaptive exponential integrate-and-fire neurons that is stimulated with Poissonian excitatory input. For such a network one would expect that groups of neurons show a similar activity as the network as a whole. However, we observe that there is a difference between the evolution of network activity and sets of neurons clustered according to their correlation. When analyzing medium spiny neuron calcium imaging data, we again find that the results of the two methods are not in line. Acknowledgements Partially funded by the German Federal Ministry of Education and Research (BMBF 01GQ0420 to BCCN Freiburg, BMBF GW0542 Cognition and BMBF 01GW0730 Impulse Control), EU Grant 269921 (BrainScaleS), Helmholtz Alliance on Systems Biology (Germany), Neurex, the the Junior Professor Program of Baden-Württemberg and the Erasmus Mundus Joint Doctoral programme EuroSPIN.