Fuel injection mixing is one of the critical factors affecting the energy conversion efficiency and emission level of thermal engines. The effect of thermodynamic conditions on mixing characteristics of supercritical cryogenic nitrogen jet under varicose mode excitation is investigated using the unsteady Reynolds-averaged Navier-Stokes method combined with real-gas thermodynamics and transport properties of nitrogen in NIST database. The ambient-to-jet density ratio is defined to represent different thermodynamic conditions and is found to affect the jet mixing enhancement directly. As the density ratio increases from 0.098 to 0.432, the density gradient reduces in the jet shear layer, mitigating flow stratification. Jet mixing is enhanced with a reduction of density potential core length by 24 % and a tripled density spreading angle. Under varicose mode excitation, large vortices are formatted close to the jet orifice, especially for higher density ratio cases. The peak of the jet turbulent kinetic energy is higher and shifts upstream as density ratio increasing. The jet mixing enhancement is further achieved, with the spreading angle increment growing from 1° to 4° and the velocity decay rate increasing from 0.03 to 0.15. As the excitation amplitude rising from 5 % to 15 %, the growth of jet momentum instability in the jet potential core breaks the velocity gradients inhibition on jet mixing. The supercritical jet enters self-similar region earlier, with density potential core length shortened by 51 % and spreading angle increased by 28 % at a middle density ratio of 0.275.