Jagiellonian Positron Emission Tomograph Research Articles

Review of physics program at J-PET

The Jagiellonian - Positron Emission Tomograph (J-PET) is a multi purpose detector for tests of discrete symmetries and quantum entanglement of photons originating from the decay of positronium atoms. The research is per formed by measurement of angular correlations between photons from the an nihilations of the lightest leptonic bound system. The J-PET detector is the only device which enables determination of polarisation of photons from positronium annihilation together with estimation of positronium spin axis on the event-by-event basis. The novelty of the system is based on a usage of plastic scintil-lators as active detection material and trigger-less data acquisition system. The aim of two independent detection setups currently in use together with different annihilation chambers is to improve limits on C, CP and CPT symmetries and to search for the entanglement of photons originating from electron-positron annihilation. Additionally a precise measurement of ortho-positronium life time would allow to test of non-relativistic quantum electrodynamics and search for Mirror Matter.

Efficiency determination of J-PET: first plastic scintillators-based PET scanner

BackgroundThe Jagiellonian Positron Emission Tomograph is the 3-layer prototype of the first scanner based on plastic scintillators, consisting of 192 half-metre-long strips with readouts at both ends. Compared to crystal-based detectors, plastic scintillators are several times cheaper and could be considered as a more economical alternative to crystal scintillators in future PETs. JPET is also a first multi-photon PET prototype. For the development of multi-photon detection, with photon characterized by the continuous energy spectrum, it is important to estimate the efficiency of J-PET as a function of energy deposition. The aim of this work is to determine the registration efficiency of the J-PET tomograph as a function of energy deposition by incident photons and the intrinsic efficiency of the J-PET scanner in detecting photons of different incident energies. In this study, 3-hit events are investigated, where 2-hits are caused by 511 keV photons emitted in e^+e^- annihilations, while the third hit is caused by one of the scattered photons. The scattered photon is used to accurately measure the scattering angle and thus the energy deposition. Two hits by a primary and a scattered photon are sufficient to calculate the scattering angle of a photon, while the third hit ensures the precise labeling of the 511 keV photons.ResultsBy comparing experimental and simulated energy distribution spectra, the registration efficiency of the J-PET scanner was determined in the energy deposition range of 70–270 keV, where it varies between 20 and 100%. In addition, the intrinsic efficiency of the J-PET was also determined as a function of the energy of the incident photons.ConclusionA method for determining registration efficiency as a function of energy deposition and intrinsic efficiency as a function of incident photon energy of the J-PET scanner was demonstrated. This study is crucial for evaluating the performance of the scanner based on plastic scintillators and its applications as a standard and multi-photon PET systems. The method may be also used in the calibration of Compton-cameras developed for the ion−beam therapy monitoring and simultaneous multi-radionuclide imaging in nuclear medicine.

Comparative studies of plastic scintillator strips with high technical attenuation length for the total-body J-PET scanner

Plastic scintillator strips are considered as one of the promising solutions for the cost-effective construction of total-body positron emission tomography, (PET) system. The purpose of the performed measurements is to compare the transparency of long plastic scintillators with dimensions 6 mm × 24 mm × 1000 mm and with all surfaces polished. Six different types of commercial, general purpose, blue-emitting plastic scintillators with low attenuation of visible light were tested, namely: polyvinyl toluene-based BC-408, EJ-200, RP-408, and polystyrene-based Epic, SP32 and UPS-923A. For determination of the best type of plastic scintillator for total-body Jagiellonian positron emission tomograph (TB-J-PET) construction, emission and transmission spectra, and technical attenuation length (TAL) of blue light-emitting by the scintillators were measured and compared. The TAL values were determined with the use of UV lamp as excitation source, and photodiode as light detector. Emission spectra of investigated scintillators have maxima in the range from 420 nm to 429 nm. The BC-408 and EJ-200 have the highest transmittance values of about 90% at the maximum emission wavelength measured through a 6 mm thick scintillator strip and the highest technical attenuation length reaching about 2000 mm, allowing assembly of long detection modules for time-of-flight (TOF) J-PET scanners. Influence of the 6 mm × 6 mm, 12 mm × 6 mm, 24 mm × 6 mm cross-sections of the 1000 mm long EJ-200 plastic scintillator on the TAL and signal intensity was measured. The highest TAL value was determined for samples with 24 mm × 6 mm cross-section.

Potential of modular J-PET for applications in the field of particle and medical physics

Modular J-PET is the new prototype of the Jagiellonian Positron Emission Tomograph. The portability feature due to its modular design makes it a unique tomograph with a larger axial field of view of 50 cm. The complete ring is composed of 24 modules that can be configured as a diagnostic chamber with a diameter of approximately 76 cm or as a detection setup consisting of several modules for experimental studies where multiple photons are generated in a single event. The J-PET collaboration explicitly studies the decays of the positronium atom (Ps), which is a bound state of electron and positron that self-annihilate into multiple photons. The modular J-PET provides a significant phase space covrage for the registration of photons originating from the decays of Ps atoms. In this paper, we discuss the properties of the modular J-PET and its potential applications in medical and particle physics.

Technical Attenuation Length Measurement of Plastic Scintillator Strips for the Total-Body J-PET Scanner

The aim of the performed technical attenuation length measurement is to compare light attenuation of a few commercially available plastic scintillator strips and to select the best scintillator type for the total-body Jagiellonian Positron Emission Tomograph (J-PET) construction. Few models of plastic scintillators obtained from different manufacturers were tested. All strips had the same rectangular cross section and dimensions 6 mm $\times \,\,24$ mm $\times \,\,1000$ mm with all surfaces polished. The light attenuation length was measured by exciting the scintillator strip at different positions with an ultraviolet lamp emitting at 365 nm and reading light signal collected at one side of the strip by a silicon photodiode. Among measured plastic scintillators, EJ-200 possesses the highest technical light attenuation length and is suitable for construction of total-body J-PET scanner.

Influence of Cosmic Radiation while Testing the Time Reversal Symmetry in the Decay of Ortho-Positronium Atoms using the J-PET detector

This article reports the influence of cosmic radiation interaction while testing the T-symmetry in metastable triplet states of positronium with the Jagiellonian-Positron Emission Tomograph (J-PET) detector. The J-PET detector developed at Jagiellonian University in Krakow, Poland is one of its kind being based on organic scintillators. J-PET is an axially symmetric and high acceptance scanner that can be used as a multi-purpose detector system. It is well suited to pursue tests of discrete symmetries in decays of positronium in addition to medical imaging. Cosmic rays have been considered as a well known source of background while performing test measurements with the J-PET detector. It is important to estimate and reject the significant contribution of the cosmic ray interactions within the J-PET detector in order to improve the sensitivity while testing T-symmetry violation. Therefore, the results of cosmic radiation uniquely being separated due to their large energy deposits in plastic scintillator detectors are shown in this article.

Tests of discrete symmetries in positronium decays with the J-PET detector

The newly constructed Jagiellonian Positron Emission Tomograph (J-PET) is the first tomograph built from plastic scintillators. As a detector optimized for the registration of photons from the electron-positron annihilations, it also capable to tests discrete symmetries in decays of positronium atoms via the determination of the expectation values of the discrete-symmetries-odd operators, which may be constructed from the spin of ortho-positronium atom and the momenta and polarization vectors of photons originating from its annihilation.

Search for the Charge Symmetry Forbidden Decays of Electron--Positron Bound State Using the J-PET Detector

The Jagiellonian positron emission tomograph (J-PET) is a multi-purpose device built out of plastic scintillators. With large acceptance and high angular resolution, it is suitable for the studies of various phenomena such as discrete symmetries in decay of positronium atom or entangled states of photons as well as medical imaging. J-PET enables the measurement of momenta together with photon polarization related observables. Large acceptance and high granularity of the J-PET detector enables measurement of ortho-positronium decays into three photons in the whole phase-space. In this paper we present the search of the C-forbidden decays of positronium with the J-PET detector.

Towards Time Reversal Symmetry Test with o-Ps Decays Using the J-PET Detector

One of the features of the triplet state of positronium (ortho-Positronium)atoms is its relatively longer lifetime when compared to the singlet states ofpositronium (para-Positronium) atoms. The most probable decay of ortho-Positronium is into three annihilation photons. In order to test the discretesymmetry using the time-reversal symmetry odd-operator, it is importantto identify ortho-Positronium decay. Identification of the decay of ortho-Positronium atoms by measuring the positronium annihilation lifetime withthe Jagiellonian-Positron Emission Tomograph (J-PET) is presented in this article.

Study of the time reversal symmetry in the decay of ortho-Positronium atoms using the J-PET detector

The Jagiellonian Positron Emission Tomograph (J-PET) is a novel device based on organic scintillators being developed at Jagiellonian University in Kraków, Poland. J-PET is an axially symmetric and high acceptance scanner that can be used as a multi-purpose detector system. It is well suited to pursue tests of discrete symmetries in decays of positronium in addition to medical imaging. J-PET enables measurement of both momenta and polarization vectors of annihilation photons. The latter is a unique feature of the J-PET detector which allows study of the time reversal symmetry violation operator constructed solely from the annihilation photons momenta before and after scattering within the detector.

The tests of CP and CPT symmetry using the J-PET detector

Symmetries under the parity transformation (P), charge-conjugation (C) and time reversal (T) are of fundamental importance in nuclear and elementary particle physics. Studies of the observables violating the combined CP symmetry constitute precise tests of the Standard Model. However, CP violation was observed to date only for systems involving quarks, raising the importance of searches its manifestations e.g. in purely leptonic systems. The 3γ decay of spin-aligned ortho-positronium atoms (o-Ps) can be used to test CP invariance in such a purely leptonic system. The Jagiellonian Positron Emission Tomograph (J-PET) detection system enables experimental tests of CP and CPT through measurement of the expectation values of angular correlation operators odd under these transformations and constructed from (i) spin vector of the ortho-positronium atom, (ii) co-planar momentum vectors of photons originating from the decay of the positronium atom, and (iii) linear polarization direction of annihilation photons. Precise experimental symmetry tests with J-PET are possible thanks to a dedicated reconstruction technique of 3γ ortho-positronium decays and a positronium production chamber including a highly porous aerogel target, whose setup allows for determining the orthopositronium spin polarization without the use of an external magnetic field.

Time Over Threshold as a measure of energy response of plastic scintillators used in the J-PET detector

The Jagiellonian Positron Emission Tomograph (J-PET) is a multipurpose detector being developed to provide an economical alternative of commercially available PETs as well as to perform the tests on the discrete symmetries and entanglement. It is composed of 192 plastic scintillators axially arranged in three cylindrical layers. In the framework of J-PET detector, Time-Over-Threshold (TOT) approach is adopted for the signal readouts in order to utilize the excellent time resolution of the plastic scintillators. In this paper, we present a method elaborated for establishing a relation between TOT and energy loss.

A feasibility study of the time reversal violation test based on polarization of annihilation photons from the decay of ortho-Positronium with the J-PET detector

The Jagiellonian Positron Emission Tomograph (J-PET) is a novel device being developed at Jagiellonian University in Krakow, Poland based on organic scintillators. J-PET is an axially symmetric (M. Mohammed) has been affiliated to affiliation 6. Please check if correct, otherwise, provide the correct affiliation.and high acceptance scanner that can be used as a multi-purpose detector system. It is well suited to pursue tests of discrete symmetries in decays of positronium in addition to medical imaging. J-PET enables the measurement of both momenta and the polarization vectors of annihilation photons. The latter is a unique feature of the J-PET detector which allows the study of time reversal symmetry violation operator which can be constructed solely from the annihilation photons momenta before and after the scattering in the detector.

Commissioning of the J-PET detector in view of the positron annihilation lifetime spectroscopy

The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET device built from plastic scintillators. It is a multi-purpose detector designed for medical imaging and for studies of properties of positronium atoms in porous matter and in living organisms. In this article we report on the commissioning of the J-PET detector in view of studies of positronium decays. We present results of analysis of the positron lifetime measured in the porous polymer. The obtained results prove that J-PET is capable of performing simultaneous imaging of the density distribution of annihilation points as well as positron annihilation lifetime spectroscopy.

Studies of discrete symmetries in decays of positronium atoms

A positronium - a bound state of electron and positron - is an eigenstate of parity and charge conjugation operators which decays into photons. It is a unique laboratory to study discrete symmetries whose precision is limited, in principle, by the effects due to the weak interactions expected at the level of 10−14 and photon-photon interactions expected at the level of 10−9. The Jagiellonian Positron Emission Tomograph (J-PET) is a detector for medical imaging as well as for physics studies involving detection of electronpositron annihilation into photons. The physics case covers the areas of discrete symmetries studies and genuine multipartite entanglement. The J-PET detector has high angular and time resolution and allows for determination of spin of the positronium and the momenta and polarization vectors of annihilation quanta. In this article, we present the potential of the J-PET system for studies of discrete symmetries in decays of positronium atoms.

J-PET: A New Technology for the Whole-body PET Imaging

The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET built from plastic scintillators. J-PET prototype consists of 192 detection modules arranged axially in three layers forming a cylindrical diagnostic chamber with the inner diameter of 85 cm and the axial field-of-view of 50 cm. An axial arrangement of long strips of plastic scintillators, their small light attenuation, superior timing properties, and relative ease of the increase of the axial field-of-view opens promising perspectives for the cost effective construction of the whole-body PET scanner, as well as construction of MR and CT compatible PET inserts. Present status of the development of the J-PET tomograph will be presented and discussed.

Commissioning of the J-PET Detector for Studies of Decays of Positronium Atoms

The Jagiellonian Positron Emission Tomograph (J-PET) is a detector for medical imaging of the whole human body as well as for physics studies involving detection of electron-positron annihilation into photons. J-PET has high angular and time resolution and allows for measurement of spin of the positronium and the momenta and polarization vectors of annihilation quanta. In this article, we present the potential of the J-PET system for background rejection in the decays of positronium atoms.

Novel J-PET scanner combined with positron annihilation lifetime spectroscopy technique as a tool for morphometric imaging

Positron Annihilation Lifetime Spectroscopy (PALS) allows examining structure of materials at nano and sub-nanometer level. This technique is based on the lifetime and production intensity of ortho-positronium atoms in free volumes of given structures. It is mostly used for studies of organic materials. However there exist also few results, e.g. by groups of Y. C. Jean and R. Pietrzak, showing that morphology of cells is correlated with the PALS parameters. Jagiellonian Positron Emission Tomograph (J-PET) is a multi-purpose detector which will be used for investigations with positronium atoms in life-sciences as well as for medical diagnostics. Such prototype based on plastic scintillators and fully compatible with MRI is currently being developed at the Jagiellonian University in Krakow, Poland. In this talk results of the first experiments conducted by the J-PET collaboration will be presented. We performed PALS studies of well known structures such as silica and of some model micro-organisms, e.g. Saccharomyces cerevisiae both with dry and aqueous samples allowing to determine the correlation between hygroscopicity of the cell and PALS parameters. As a result, we proved that PALS can be successfully used for studies of living organisms their dynamics and its relation to the cells morphology. This result opens perspective for simultaneous determination of early and advanced stages of carcinogenesis by observing changes in biomechanical parameters between normal and tumour cells and standard PET examination. J-PET detection system combined with PALS technique will be more accurate and affordable for cancer diagnostics. Disclosure Authors disclose any relationship that may bias the presentation.

A feasibility study of ortho-positronium decays measurement with the J-PET scanner based on plastic scintillators.

We present a study of the application of the Jagiellonian positron emission tomograph (J-PET) for the registration of gamma quanta from decays of ortho-positronium (o-Ps). The J-PET is the first positron emission tomography scanner based on organic scintillators in contrast to all current PET scanners based on inorganic crystals. Monte Carlo simulations show that the J-PET as an axially symmetric and high acceptance scanner can be used as a multi-purpose detector well suited to pursue research including e.g. tests of discrete symmetries in decays of ortho-positronium in addition to the medical imaging. The gamma quanta originating from o-Ps decay interact in the plastic scintillators predominantly via the Compton effect, making the direct measurement of their energy impossible. Nevertheless, it is shown in this paper that the J-PET scanner will enable studies of the text{ o-Ps }rightarrow 3gamma decays with angular and energy resolution equal to sigma (theta ) approx {0.4^{circ }} and sigma (E) approx 4.1,{mathrm{keV}}, respectively. An order of magnitude shorter decay time of signals from plastic scintillators with respect to the inorganic crystals results not only in better timing properties crucial for the reduction of physical and instrumental background, but also suppresses significantly the pile-ups, thus enabling compensation of the lower efficiency of the plastic scintillators by performing measurements with higher positron source activities.

Beam Profile Investigation of the New Collimator System for the J-PET Detector

Jagiellonian Positron Emission Tomograph (J-PET) is a multi-purpose detector which will be used for search for discrete symmetries violations in the decays of positronium atoms and for investigations with positronium atoms in life-sciences and medical diagnostics. In this article we present three methods for determination of the beam profile of collimated annihilation gamma quanta. Precise monitoring of this profile is essential for time and energy calibration of the J-PET detector and for the determination of the library of model signals used in the hit-time and hit-position reconstruction. We have we have shown that usage of two lead bricks with dimensions of 5x10x20 cm^3 enables to form a beam of annihilation quanta with Gaussian profile characterized by 1 mm FWHM. Determination of this characteristic is essential for designing and construction the collimator system for the 24-module J-PET prototype. Simulations of the beam profile for different collimator dimensions were performed. This allowed us to choose optimal collimation system in terms of the beam profile parameters, dimensions and weight of the collimator taking into account the design of the 24 module J-PET detector.