Irritative Lower Urinary Symptoms Research Articles

Bladder Metastatic Breast Cancer Presenting Initially with Lower Urinary Tract Symptoms: A Rare Case Report

Introduction: Breast cancer (BC) is the most frequently diagnosed malignancy (25% of all cancers) and the leading cause of cancer-related death in women; death is mainly attributed to the metastatic spread of the primary tumor. On the other hand, secondary tumors of the bladder are rare, representing 2% of all bladder neoplasms. Breast cancer rarely spreads to the urinary bladder. Patients in almost all previous reports have been diagnosed with BC several months before the bladder metastasis (BM) was discovered. Case Presentation: A 67-year-old woman presented with irritative bladder symptoms with no history suggestive of BC. Normal breast examination and normal laboratory investigations with Breast Imaging Reporting and Data System 1 (BI-RADS 1) in mammographic evaluation challenged the pathological findings of the bladder biopsy that was positive for metastatized BC to the bladder. Conclusions: Metastatic BC may rarely initially present with irritative lower urinary symptoms and absent clinical and radiological features of BC-but positive histopathological findings.

Successful management of ectopic kidney stones in a patient with situs inversus totalis: a rare case report

BackgroundSitus inversus totalis is a very rare congenital anatomical variation, in which all thoracic and abdominal organs are right-left inverted. This condition is associated with an increased risk of organ malformations including ectopic kidney, which is a very rare combination.Case presentationA 56-year-old male presented with colicky left iliac pain associated with nausea, vomiting, and irritative lower urinary symptoms. The patient has a medical history of recurrent lower urinary infections and a family history of situs inversus totalis. Radiological images demonstrated dextrocardia, situs inversus totalis of all the abdominal organs, and an ectopic pelvic kidney on the left side, with 4 stones inside it. Left nephrectomy was performed due to extensive renal damage. At discharge and during follow-up, the patient's condition was satisfactory and stable.ConclusionsThe ectopic kidney may present diagnostic and therapeutic challenges when associated with situs inversus.