AbstractThere is a lack of nitrogen response research on dark red kidney beans (Phaseolus vulgaris L.). This is of particular importance as most cultivars form nodules and are commonly grown on sandy soil. The objectives of this study were to determine the effects of nitrogen rates and irrigation amounts on leaf area index, white mold occurrence, yield, and N uptake of dark red kidney beans. The study occurred at the University of Wisconsin Hancock Agricultural Research Station over two growing seasons (2020 and 2021), across four N rates, three irrigation levels, and five cultivars. Preceding crop for each study year was potato and field corn, respectively. More heavy rainfall events that may lead to leaching were observed in 2021. Neither irrigation effect nor general cultivar difference was observed on bean yield, disease resistance, and nitrogen use across the 2 years. Bean yield was significantly influenced by N rates across the five cultivars in 2020 but not in 2021, with 56 kg ha−1 more total N uptake at the lowest N rate in 2021. This highlights large site‐year influences on N supply from fixation. Furthermore, although greater N application did lead to greater yield in 1 year, it was also associated with greater white mold disease pressure and lower partial factor productivity (PFP). Thus, there is economic risk in N application to dark red kidney beans on irrigated sandy soil from reduced quality (mold damage) and lower N use efficiency (indicated by lower PFP), although site‐year effects remain unknown.