Ipsilateral Seminal Vesicle Cyst Research Articles

A case with an ectopic ejaculatory duct opening into the bladder trigone in Zinner syndrome, congenital unilateral renal agenesis, and an ipsilateral seminal vesicle cyst

IntroductionThis report describes a case with an ectopic ejaculatory duct opening into the bladder trigone in Zinner syndrome, congenital unilateral renal agenesis, and an ipsilateral seminal vesicle cyst.Case presentationThe patient was identified when no left kidney was detected in the fetal period. Abdominal ultrasonography and pelvic plain MRI at 6 months old revealed a 10‐mm cystic lesion on the dorsal aspect of the bladder. Cysto‐urethroscopy at 1 year old revealed a rather short posterior urethra and right and left inferior crests extending from the posterior urethra beyond the bladder neck. The ejaculatory duct opening was identified on the bladder trigone.ConclusionAnatomical abnormality of the ejaculatory duct may represent a cause of infertility and ejaculatory dysfunction in Zinner syndrome. Endoscopic evaluation should be performed for this rare anomaly, even in children.

Incidental Zinner Syndrome in Nigeria: A Case Report

Zinner syndrome (ZS) is a rare urogenital condition characterised by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction, resulting from malformation during early embryogenesis of the mesonephric (Wolffian) duct. The authors present a 35-year-old male who was being evaluated for chronic hepatitis B virus infection. He was referred to the urology outpatient clinic on account of incidental ultrasound finding of solitary right kidney. General physical examination revealed a healthy-looking young male with a flat abdomen and no palpable enlarged organs. Digital rectal examination revealed normal sized prostate with no palpable pararectal masses. MRI of the pelvis revealed a triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. The clinical diagnosis was asymptomatic ZS. He is on yearly follow-up at the urology outpatient clinic for lower urinary tract symptoms, pelvic pain, painful ejaculation, features of infertility, and pelvic ultrasound. If any of these symptoms occur, he will be treated with an α-adrenergic receptor blocker, drainage of the seminal vesicle cyst, and appropriate treatment for infertility. He is also on active surveillance for viral hepatitis by the gastroenterology team. In conclusion, prompt referral and comprehensive radiological imaging investigations of patients with unilateral agenesis of the kidney will lead to increased identification and report of patients with ZS. There is paucity of literature reports on ZS in the authors’ environment, and this case report, to the best of the authors’ knowledge, is the first from Nigeria.

Clinicopathological and genetic features of Zinner’s syndrome: two case reports and review of the literature

Zinner’s syndrome (ZS) is a rare congenital malformation due to abnormal development of the urogenital tract. It is characterized by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst and ipsilateral ejaculatory duct obstruction. Cases are rarely reported in China since the incidence of the disease is low. Symptoms also vary widely among patients and its etiology is unclear. In this article, we described two patients with totally different cinicopathological and genetic features based on exon sequencing.

Zinner’s Syndrome: Case report of a Developmental Anomaly of the Mesonephric Duct

Zinner’s syndrome is a rare congenital malformation characterized by the association of unilateral renal agenesis with ipsilateral seminal vesicle cyst and ejaculatory duct obstruction. Most patients are asymptomatic until the third or fourth decade of life when the syndrome is associated with dysuria, perineal pain, infertility, and painful ejaculation. In this report, we present the common imaging findings of this rare developmental anomaly involving the mesonephric duct in a 48-year-old male patient experiencing pelvic pain, recurrent dysuria, and pollakiuria.

A rare case of Zinner syndrome with unilateral testicular agenesis and aberrant course of left common iliac artery

BackgroundZinner syndrome is a rare Wolffian duct anomaly presenting as a triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst and ipsilateral ejaculatory duct obstruction. The condition is due to a developmental anomaly leading to malformation of the mesonephric duct. Magnetic resonance imaging is considered to be the gold standard for the diagnosis of Zinner syndrome. Due to the limited number of cases reported in the literature, the associations of Zinner syndrome are not well established. Case presentationIn this case report, we are presenting a case of a 38-year-old male with dysuria, intermittent pain in the scrotum and lower abdomen and painful ejaculation for the past six months. Imaging findings led to the diagnosis of Zinner syndrome, with unilateral testicular agenesis and an aberrant course of the left common iliac artery.ConclusionsApart from the known associations of Zinner syndrome, testicular agenesis in a patient with Zinner syndrome has not been reported in the literature and is an important addition to the limited literature available.

Role of magnetic resonance imaging in evaluation of ejaculatory duct in Zinner’s syndrome: case series of five patients and review of the literature

BackgroundZinner's syndrome is a mesonephric duct anomaly characterized by unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction due to insult occurred at urogenital tract embryogenesis during the first trimester. In the third and fourth decades of life, it is frequently diagnosed when patients begin to be symptomatic, such as lower urinary tract symptoms, infertility and painful ejaculation.Case presentationHerein we illustrate case review including five patients diagnosed as Zinner’s syndrome, three of them complaining from infertility; however, the remaining two cases were fertile and incidentally diagnosed.ConclusionsRadiological investigations play significant role in the diagnostic and management processes including US, CT and MRI for detecting ipsilateral renal agenesis and unilateral seminal vesicles dilatation, but evaluation of ejaculatory duct can be done only by MRI and transrectal ultrasound; however, the latter may be sometimes nonconclusive or intolerable by patients, so MRI is considered the golden modality with its high capability to assess the lower male genital tract which played a significant role in our case series starting with detection of the presence or absence of the ejaculatory duct obstruction as well as the high delineation of the origin and nature the seminal vesicle cyst including also its size and content and finally by detection of the communication between ureteral bud and the seminal vesicles cystic dilatation.

Zinner syndrome – a rare radiological diagnosis in a young male presenting with recurrent dysuria

Zinner syndrome is a rare congenital abnormality of the mesonephric (Wolffian) duct consisting of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. The syndrome usually presents in the second or third decade of life mainly after the beginning of sexual activity and usually in the form of voiding manifestations. The main imaging modality is magnetic resonance imaging (MRI); however, usually suspected in transabdominal sonography, which may give initial clue to the diagnosis. Herein, we report a rare case of a 24 - year male with right renal agenesis with cystic pelvic mass diagnosed as Zinner syndrome via multimodality imaging.

Zinner Syndrome.

Zinner syndrome is a developmental anomaly of the urogenital tract. This condition is defined by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst and ipsilateral ejaculatory duct obstruction. The syndrome is due to malformation of the mesonephric duct during embryogenesis. The condition used to be rare but is now frequently encountered due to the advent of MRI and CT. MRI confirms the diagnosis by revealing the seminal vesicle cyst and its contents, and the ejaculatory duct obstruction, while CT confirms renal agenesis. We report the case of a young patient with Zinner syndrome.LEARNING POINTSZinner syndrome consists of the triad of renal agenesis, seminal vesicle cyst and ejaculatory duct obstruction.Any insult during embryogenesis of the mesonephric duct in men can result in Zinner syndrome.Pelvic MRI is the gold standard to confirm the diagnosis of Zinner syndrome.

Zinner syndrome: A case report of rare urogenital anomaly

Zinner Syndrome is a rare urogenital tract anomaly with unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. The syndrome occurs due to an insult to the development of the paramesonephric duct during embryogenesis. Patients may present late due to dysejaculation as a result of obstruction of the ejaculatory duct or commonly remain asymptomatic. Here, we present such a case presenting with dysejaculation which was diagnosed with Zinner syndrome on ultrasound.

Синдром Циннера у детей

In this article, we report three cases of Zinner syndrome (renal agenesis or renal dysplasia, ipsilateral seminal vesicle cyst, and seminal duct obstruction) in children of different age and describe their diagnosis and treatment. All patients have undergone kidney and bladder ultrasonography, renal scintigraphy, and cystoscopy. Two children have also undergone contrast-enhanced computed tomography; one child has undergone magnetic resonance imaging. A 6-month-old patient with a large cyst and clinical manifestations of infravesical obstruction and chronic constipation was operated on. He has undergone diagnostic laparoscopy and cyst removal; seminal duct atresia was confirmed intraoperatively. Key words: Zinner syndrome, renal agenesis, seminal vesicle cyst

ZINNER SYNDROME

Developmental malformations of the urogenital tract are rare, and most of them are cystic anomalies. In the embryogenesis, exactly during the first trimester of gestation developmental arrest affecting mesonephric (Wolffian) duct results in unilateral renal agenesis. Ipsilateral seminal vesicle cyst also affecting the caudal end of Mullerian duct produces ipsilateral ejaculatory duct obstruction. Most of the patients with this malformation are asymptomatic until the 2nd or 3rd decade of life. Initially, majority of patients have nonspecific symptoms such as perineal discomfort, urinary urgency, prostatism, painful ejaculation and dysuria. We report an uncommon case of a 24-year-old patient presented with symptoms of lower urinary tract irritation. Radiologic imaging modalities as ultrasonography, contrast-enhanced computed tomography and magnetic resonance imaging are all helpful in diagnosis of this extremely rare developmental anomaly. Keywords: MRI, seminal vesicles, ejaculatory duct, CT. https://doi.org/10.55302/JMS2143171s

Zinner’s Syndrome: A Confusing Diagnosis in the Face of Chronic Disabling Perineoscrotal Pain in the Young Subject, about a Case

Zinner syndrome is a rare congenital malformation related to an abnormality in the development of the Wolffian duct, the clinical picture of which consists of a triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and obstruction of the ejaculatory duct. Chronic perineoscrotal pain may be an indication of the diagnosis of Zïnner syndrome to some extent. We report the observation of a 23-year-old patient, married and father of one child, who presented with chronic perineo-scrotal pain revealing on morphological assessment (ultrasound, uroscanner, prostatic MRI) a cystic formation of the seminal vesicle, left renal agenesis with an empty left renal compartment. Given the patient’s refusal of any surgical procedure, treatment consisted of echo-guided puncture of the seminal vesicle cyst bringing back 30 cc of a seroviscous liquid whose analysis revealed spermatozoa, without atypical cells, compatible with a cyst. The clinical evolution was marked by a progressive remission of the scrotal pain with a delay of several months.

Rare Cause of Painful Ejaculation – Zinner’s Syndrome: A Case Report

Zinner’s syndrome is a rare congenital abnormality consisting of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. The mutual embryological origins of the seminal vesicle and the ureteral bud from the Wolffian duct result in both anomalous seminal vesicle and urinary tracts. Most cases have nonspecific symptoms such as prostatism, urinary urgency, dysuria, painful ejaculation, and perineal discomfort. The usual presentation is between the third and fourth decades of life, with infertility being the most common complaint. Ultrasound and magnetic resonance imaging can easily detect this condition. We present here an extremely rare developmental anomaly involving the Wolffian ducts, which would remain undiagnosed but for radiologic imaging.

A rare case of abdominal pain.

A rare case of abdominal pain.

Squamous cell carcinoma of the seminal vesicle from zinner syndrome: a case report and review of literature.

Until now, fewer than 60 cases of tumors originating from the seminal vesicle have been reported. Most of them were adenocarcinoma, cystadenoma, and benign mesenchymal tumor [1]. Among them, only three cases in the English literature have been reported as squamous cell carcinoma [2-4]. Although all three cases had a prolonged history of stone formation or chronic inflammation, none of them were associated with congenital malformation of the urogenital system such as Zinner syndrome. Zinner syndrome is a rare Mullerian duct abnormality consisting of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. Herein, we report a 41-year-old male with Zinner syndrome, who developed a poorly differentiated squamous cell carcinoma of the seminal vesicle as a result of prolonged inflammation.

Minimal Invasive Approach should become the Standard for the Management of Zinner Syndrome

The presence of a renal agenesis with an ipsilateral seminal vesicle cyst and an ejaculatory duct obstruction is a rare congenital anomaly initially reported by Zinner in 1914. This anomaly can be responsible of perineal pain, hemospermia, hematuria, post-ejaculatory pain, urinary tract infection, infertility and lower urinary tract symptoms (LUTS).

Epididymal tissue in the dilated portion of a dysgenetic kidney with an ipsilateral seminal vesicle cyst and ectopic ureteral insertion

Epididymal tissue in the dilated portion of a dysgenetic kidney with an ipsilateral seminal vesicle cyst and ectopic ureteral insertion

Zinner syndrome: A unique triad of mesonephric duct abnormalities as an unusual cause of urinary symptoms in late adolescence

The present article reports a triad of right renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction (Zinner syndrome) in a 19-year boy who presented with urinary symptoms. A detailed review of the relevant literature is also presented.