Sources Of Ionizing Radiation Research Articles

Biological Efficacy of Ionizing Radiation Sources on 3D Organotypic Tissue Slices Assessed by Fluorescence Microscopy.

Traditional cell-based radiobiological methods are inadequate for assessing the toxicity of ionizing radiation exposure in relation to the microstructure of the extracellular matrix. Organotypic tissue slices preserve the spatial organization observed in vivo, making the tissue easily accessible for visualization and staining. This study aims to explore the use of fluorescence microscopy of physiologically compatible 3D tissue cultures to assess the effects of ionizing radiation. Organotypic tissue slices were obtained by vibratome, and their mechanical properties were studied. Slices were exposed by two ionizing radiation sources; electron beams (80 Gy and 4 Gy), and soft gamma irradiation (80 Gy and 4 Gy). Two tissue culture protocols were used: the standard (37°C), and hypothermic (30°C) conditions. A qualitative analysis of cell viability in organotypic tissue slices was performed using fluorescent dyes and standard laser confocal microscopy. Biological dosimetry is represented by differentially stained 200-µm thick organotypic tissue sections related to living and dead cells and cell metabolic activity. Our results underscore the ability of fluorescence laser scanning confocal microscopy to rapidly assess the radiobiological effects of ionizing radiation in vitro on 3D organotypic tissue slices.

Clinical guidelines for prevention, diagnostics, treatment and recovery from acute radiation injuries: classification and basic pathology

The provision of state guarantees to citizens with medical care is achieved by compliance with clinical recommendations by medical organizations. However, acute diseases (conditions) caused by excess radiation were excluded from the relevant pathologies for the development of appropriate clinical recommendations. The current events increase the relevance of acute radiation pathology for the healthcare system and determine the high risk of such cases among the personnel of radiation-hazardous facilities and population. The necessity of developing national clinical guidelines for the prevention, diagnosis, treatment, and rehabilitation of acute radiation injury victims is substantiated. Based on an analytical review of the databases of NEB, PubMed, and Medline for 1970 to 2023 on the problem of prevention, diagnosis, treatment, and rehabilitation of individuals exposed to excess radiation and analysis of the regulatory framework governing the process of creating clinical recommendations in the Russian Federation on the provision of medical care to victims of acute radiation injuries, the main terms and their definitions relevant to acute radiation pathology were formulated, which must be unified when developing clinical recommendations. The basic classification of acute radiation lesions is presented, systematizing the variety of possible clinical forms of diseases (conditions) and their etiopathogenetic variants based on the characteristics of the types of ionizing radiation sources and individual characteristics of the conditions of acute radiation exposure. Variants of working clinical classifications of acute radiation lesions based on the generalization of the experience in the country and the world on the systematization of acute radiation pathology were determined. In general, the expediency of developing a group of clinical recommendations for the prevention, diagnosis, treatment, and rehabilitation of acute radiation injuries, covering all the various current clinical forms of diseases caused by excess (uncontrolled, unregulated, emergency) exposure, is justified. The task of determining the current list of diseases (conditions) and groups of diseases (conditions) caused by excessive human exposure in the dose range that can lead to the development of acute radiation lesions is of practical importance both for departmental medicine and the country’s healthcare system.

Развитие правовой базы в области обеспечения радиационной безопасности

Purpose: To justify the main areas of Russian legacy framework in the field of radiation safety assurance as a basis for improvement of the current standards and regulations. Material and methods: The article analyses international documents and Russian federal laws regulating different aspects of human safety and highlights the most important approaches and procedures of safety assurance proven in practice. Results: The necessity of developing new federal law “On Radiation Safety in Russian Federation” is substantiated. The article shows that internationally recognized principles of radiation safety assurance should be applied in Russia: those are the preservation principle, the responsibility principle, the continuous control principle and, in particular, the permission principle. The last principle means that what is not permitted is forbidden when it comes to handling ionizing radiation sources. The article describes the main provisions and elements of new law and details some considerations that need to be articulated and enhanced in new federal law based on positive experience of their implementation in the current federal laws on different safety aspects. Conclusion: New federal Law “On Radiation Safety in Russian Federation” should incorporate all positive experience of applying the current Federal Law of 09.01.1996 N 3-FL “On Radiation Safety of the Public” and other Russian laws regulating different aspects of human safety assurance in various fields. New law should be based on unconditional priority of protection of human life and health, present and future generations and the environment from possible radiation exposure. New law should enable interaction of the facilities whose activities are related to handling ionizing radiation sources and facilities of the infrastructure for radiation safety assurance, as well as provide connection to other regulations that set specific norms and requirements in the field of radiation safety assurance.

Extended study of the influence of europium doping on phosphate glass

The phosphate glasses with various Eu2O3 concentrations (0.1–3.0 w/w%) were synthesized and studied regarding the influence of europium dopant on the properties of irradiated phosphate glasses. During studies, samples were irradiated using two types of ionizing radiation sources (β− and γ), with obtained doses up to 40 kGy. TL studies were investigated using various methods, such as TL response vs. radiation dose and the TMax-Tstop method. To further investigate, if increasing the europium concentration affects the structure of electron traps, Computer Glow Curve Deconvolution studies linked with various heating rates methods were applied –increasing the concentration of dopant does not influence the number and energy of electron traps in irradiated samples. This fact was also supported by the results of the thermoluminescence spectrum – where no additional signals, besides wide signals from native glass were observed. OSL and IRSL studies were also conducted, for OSL we observed quenching of the signals, similar as in the TLD case. For IRSL studies all samples didn't display any signals. Finally, to understand if Eu3+ also has a “protective” effect, decreasing the yield of generating F-centers during irradiation, UV-VIS spectroscopy was used. It was established that samples doped with europium oxide possess ca. 20% lower signals at F-center maximum (at 475 nm), the building-up maximum at 320 nm was observed, characteristic of the absorption band of Eu2+. All data indicate that europium in phosphate glass is taking the role of an efficient electron quencher. This quenching phenomenon occurs in three ways: first (direct) when the ion reduction process (Eu3+→Eu2+) competes with the formation of F-centers, and second (indirect) when during heating electrons coming from F-centers were quenched by near Eu3+ ions. The third mechanism of quenching occurs through the electron's non-radiative transition induced by increased stress in the glass matrix caused by a large ionic radius of the dopant.

The Molecular Mechanisms in Senescent Cells Induced by Natural Aging and Ionizing Radiation.

This review discusses the relationship between cellular senescence and radiation exposure. Given the wide range of ionizing radiation sources encountered by people in professional and medical spheres, as well as the influence of natural background radiation, the question of the effect of radiation on biological processes, particularly on aging processes, remains highly relevant. The parallel relationship between natural and radiation-induced cellular senescence reveals the common aspects underlying these processes. Based on recent scientific data, the key points of the effects of ionizing radiation on cellular processes associated with aging, such as genome instability, mitochondrial dysfunction, altered expression of miRNAs, epigenetic profile, and manifestation of the senescence-associated secretory phenotype (SASP), are discussed. Unraveling the molecular mechanisms of cellular senescence can make a valuable contribution to the understanding of the molecular genetic basis of age-associated diseases in the context of environmental exposure.

POPULATION'S RADIATION ANXIETY STRUCTURE ANALYSIS FOR THE PRE-COVID-19 PERIOD

Introduction. A considerable amount of conflicting reports creates conditions for concern about the effects of radiation on health. The adequacy of the assessment of problems and responses to these challenges depends on the sources used by a person, his culture and education level, as well as the emotional overtone of this assessment.
 The aim of the study is to determine dynamic changes in the prevalence and structure of population’s radiation anxiety states under stable social conditions based on a psychological and hygienic assessment.
 Materials and methods: In order to research and assess the perception of Kropyvnytskyi residents about the degree and prevalence of radiation anxiety states, a survey was conducted on Facebook and Instagram social networks from February to December 2019 using Google Form. For assessment of dynamic changes in radiation anxiety, data from our own studies in 2014 were used [9]. The questionnaire methodology was based on the principles of the previously tested and patented "Methodology for determining radiation anxiety among the population" and the monograph "Radiation anxiety among the population". Three hundred and twenty four residents of Kropyvnytskyi aged 18 to 73 were included in the study, 155 (47.8%) men and 169 (52.2%) women. The average age of the interviewees (Me (LQ; HQ)) was 27 (20; 33) years old.
 Results. A specific psycho-emotional state is developed and maintained at some level in the residents of cities with nuclear power plants – radiation anxiety, which is manifested by a complex of neuropsychological and somato-physiological disorders against the fear of ionizing radiation sources background. At the same time, such a psychogenic effect may not be related to the degree of actual effects of ionizing radiation on human health. It was determined that in 2019, before the COVID-19 pandemic and Russia's full armed aggression against Ukraine, more than 90% of the surveyed residents of Kropyvnytskyi, regardless of gender and age, were concerned about potential radiation pollution of the environment and foodstuffs, medium level of radiation anxiety was in 34,9%, and high level in 14.8% . Low radiation anxiety was detected in 41.4% of respondents, and in 8.9% it was absent.
 Conclusions. Over 5 years (from 2014 to 2019), there were noticeable negative changes in the structure of the radiation anxiety states among the surveyed urban residents, namely: the amount of people without signs of radiation anxiety halved (8.9% vs. 16.0%) and respondents with the high level of this psycho-emotional state increased almost four times (14.8% versus 3.9%). The obtained results encourage the authors to future studies of specific radiation anxiety states among the population to clarify their dynamics.

USE OF CONTROL CHARTS OF CUMULATIVE AMOUNTS FOR THE METHOD OF EXTENDING THE SERVICE LIFE OF THE IONIZING RADIATION SOURCE ACCORDING TO CALIBRATION RESULTS

The article forms and substantiates the application of control charts for the method of extending the service life of the source of ionizing radiation (SIR). An algorithm for its aim was developed. The main types of con- trol charts and the features of their application were considered. A methodology for constructing a cusum map for extending the service life of SIRs based on the results of their calibrations, as well as a methodology for checking the results of SIR calibration for statistical controllability, were developed. Extrapolation methods were considered, and the method of least squares was chosen as the most optimal for this technique.

Physical and radiation shielding properties for borate, boro-tellurite, and tellurite glass system modified with different modifiers: Comparative study

Two newly synthesized glass series, 10Bi2O3-20BaO-(70-x)B2O3-xTeO2, and 10MoO3-20SrO-(70-x)B2O3-xTeO2, where x = 0, 35, and 70 mol%, were fabricated using the melt-quenching technique. The fabricated glass samples' physical properties and radiation shielding capabilities were examined. The insertion of TeO2 into the glass composition increased the density values, with the glass samples labeled BBB-T70 (6.53 g/cm3) and SBM-T70 (5.66 g/cm3) exhibiting the highest density due to the increased concentration of TeO2. The addition of TeO2 led to loosely bonded glasses, indicating lower glass stability. Using SRIM and Phy-X/PSD software, the radiation shielding capabilities of the produced samples were investigated for various radiation types, including alpha particles, protons, neutrons, and gamma rays. The increase in TeO2 content and the reduction in B2O3 revealed significant increases in the linear attenuation coefficient (LAC) values and improved gamma shielding properties. For example, the LAC values at 0.283 MeV are 0.283, 0.367, 0.667, 0.902, 1.095, 1.313, and 1.55315 cm−1 for SBM-T00, SBM-T35, SBM-T70, BBB-T00, BBB-T53, and BBB-T70, respectively. However, the SBM-T00 sample exhibited lower charged particle shielding properties. The SBT-T35 and BBB-T00 samples showed the highest ability to stop fast neutrons. In conclusion, the glass samples synthesized in this work are highly recommended for shielding against various ionizing radiation sources.

Radiation Protection of a 3D Computer Tomography Scanning Workplace for Logs-A Case Study.

Despite its undeniable advantages, the operation of a CT scanner also carries risks to human health. The CT scanner is a source of ionizing radiation, which also affects people in its surroundings. The aim of this paper is to quantify the radiation exposure of workers at a 3D CT wood scanning workplace and to determine a monitoring program based on measurements of ionizing radiation levels during the operation of a CT log scanner. The workplace is located in the Biotechnology Park of the National Forestry Centre. The ionizing radiation source is located in a protective cabin as a MICROTEC 3D CT machine with an X-ray lamp as X-ray source. The CT scanner is part of the 3D CT scanning line and its function is continuous quality scanning or detection of internal defects of the examined wood. The measurement of leakage radiation during scanning is performed with a metrologically verified meter. The measured quantity is the ambient dose equivalent rate H˙*10. The results of the measurements at the selected measurement sites have shown that, after installation of additional safety barriers, the CT scanner for the logs complies with the most strict criteria in terms of radiation protection. Workers present at the workplace during the operation of the CT scanner are not exposed to radiation higher than the background radiation level.

Preparation of pollucite ceramic matrices as 137Cs ionizing radiation source by spark plasma sintering

The paper proposes an original one-stage method using spark plasma sintering technology (SPS) of manufacturing the ionizing radiation source (IRS) of closed type with a non-dispersible ceramic core based on pollucite obtained using aluminosilicate raw materials saturated (24.3 wt%) with cesium, and doped with 10–40 wt% CsCl. According to the XRD, EDX, AAS and DTA-TG data, optimal conditions for hydrothermal synthesis zeolite NaA were established, the consolidation kinetics and phase transformations into ceramic pollucite under SPS conditions were studied. The ceramics had a relative density of 99.8 % and mechanical strength up to 732 MPa, a low rate of cesium leaching 10−7 g/cm2 day and thermal resistance in air up to 1000 °C. It was confirmed by SEM and EDX that the destruction and deformation of pollucite ceramics in the composition with CsCl and steel at the boundary of their contact in the design of the IRS product was absent and diffusion of cesium outside the ceramics did not occur. The achieved cesium content in the ceramic core of the resulting the ionizing radiation source, which meets high quality and regulatory requirements, is 44.3 wt%. The results of the study may be promising for the manufacture of industrial products.

APLIKASI PENGELOLAAN LIMBAH RADIOAKTIF BERBASIS ANDROID DI KEDOKTERAN NUKLIR RSUP DR. KARIADI

The utilization of ionizing radiation sources for diagnostics and therapy, such as radioactive substances, including radionuclides and radiopharmaceuticals, generates radioactive waste. This radioactive waste poses potential radiation hazards for workers, members of the public, and the environment. Therefore, it is crucial to manage it correctly by established regulations. Radioactive waste resulting from the utilization of Nuclear Medicine varies in terms of activity value and mass, necessitating different storage times and appropriate management. Considering these factors, this study aims to develop an Android-based application called 'Si Mbah KeCE Kariadi' (Kalkulasi Limbah Kedokteran-Nuklir Cepat dan Efektif di RSUP Dr. Kariadi) for the management of low and medium-level open radioactive waste in Nuclear Medicine. This application aims to estimate when radioactive waste can be released before being discharged to the hospital's sanitation department. The research method employed in this study involves applying the principles of radioactive waste management, specifically the decay of activity. The radioactive waste release calculator application is generated by utilizing the radioactive decay equation derived from measuring the initial radioactive waste radiation exposure rate using a survey meter radiation measuring instrument and referencing the clearance level value to estimate the release time of the radioactive waste. The evaluation of this application indicates that the radiation exposure value of the radioactive waste is equivalent to the background radiation level at its release, suggesting that it can be disposed of in the hospital sanitation department for further management as infectious waste from patients. Keywords: radioactive waste management, activity decay, application of android, nuclear medicine, clearance level.

BEST PRACTICE PERAN TIM PETUGAS PROTEKSI RADIASI (PPR) DALAM IMPLEMENTASI KESELAMATAN RADIASI DI MANDAYA ROYAL HOSPITAL PURI

Utilizing ionizing radiation sources at Mandaya Royal Hospital Puri requires strict implementation of radiation protection measures. The principles of radiation protection must be applied meticulously, considering the potential effects. The hospital has a team of radiation protection officers (RPO) comprising radiographers and medical physicists responsible for ensuring radiation safety and implementing radiation protection measures. The RPO team has conducted various radiation protection activities between January and July 2023, including monitoring radiation worker doses, optimizing patient radiation doses, conducting internal and external quality control, checking radiation protection equipment, monitoring supporting equipment related to radiation safety, socializing radiation protection across all hospital departments, and testing room radiation exposure. The RPO team has been executing their 2023 program, adhering to the best practices. The hospital management plays a crucial role in carrying out radiation protection activities, and their support and commitment are vital to the practical and sustainable implementation of the RPO team's activities. Keywords: Radiation protection officers (RPO), radiation safety culture, radiation dose, radiation protection.

Experimental study of dosimetric properties of thermoluminescent powder TLD-100

The creation of a scientifically substantiated quality assurance system for dosimetry and the optimization of medical exposure of the population of Ukraine during diagnostic and therapeutic procedures (and the possibility of dosimetric control and monitoring of emergency situations) falls within the field of the application of ionizing radiation sources (IRs). Trends in modern medicine in most countries, including Ukraine, prove a continued increase in the share of medical exposure. The main requirements and recommendations for the use of IRs for medical purposes while ensuring the radiation safety requirements for patients are provided in the documents of such International Organizations as the International Commission on Radiological Protection (ICRP), the International Atomic Energy Agency (IAEA), the World Health Organization (WHO) and the European Commission (EC).
 One of the key factors to ensure the quality of radiation therapy is metrological and dosimetric support. To enhance the effectiveness of radiation treatment and reduce the number of complications in the future, it is necessary to irradiate the local target within the patient’s body with a dose error of no more than 5%. Control of the radiation output of the therapeutic device, i.e., the calibration of the therapeutic beam used in the treatment process, is an essential element of radiation therapy.
 Radiation protection programmes are based on checking the accuracy of the calibration of remote radiotherapy devices using thermoluminescent dosimeters (TLDs) – small plastic capsules filled with thermoluminescent powder that are sent by post to radiology centres for exposure to a specific dose in a water phantom.
 Radiation therapy in Ukraine is primarily conducted using cobalt machines, X-ray therapy devices and linear accelerators.
 The results of the study include the examination of the dependency of measurement results on various exposure parameters using the automatic reader PCL-3, the determination of dosimetric characteristics of the thermoluminescent powder TLD-100, and the development of a calibration method for thermoluminescent dosimeters under standard irradiation conditions on a remote gamma therapy device.
 Therefore, the accuracy of beam calibration using TLD dosimeters has been studied, which will enable to timely detect errors in clinical dosimetry and reduce the number of cases of radiation-related complications for patients during their treatment.

Development of Gamma Flaw Detectors for Non-Destructive Testing

The radiographic method of control is implemented by a set of control tools in the form of gamma flaw detectors, which are distinguished by: mobility, reliability, radiation safety, adaptability to a wide climatic range, ease of operation, and the ability to control products with small and large radiation thicknesses. The paper describes portable gamma flaw detectors manufactured by JSC NIITFA: Gammarid 2010R, UNIGAM R, Stapel-5 Se75 Ir192, Stapel-5 Se75W, gamma flaw detector γ-RID-75/80R and stationary gamma flaw detectors RID K-100 and RID K-400. Also paper describes a brief technology for the production of ionizing radiation sources Ir-192 with activity of 120 Curie, a technology for rolling the source holder with Ir-192 source and completing the Ir-192 source with a portable gamma flaw detector Gammarid-192/120M in the INP AS.

Assessment of the clinical and hematological status in acute radiation damage of Leningrad calico chickens

The problem of radiation damage to the human body, animals, birds and its individual systems and organs against the background of the use of ionizing radiation sources has acquired relevance throughout the world over the past decades. In the event of an emergency, acute radiation damage in poultry will be massive and increase the risks of developing infectious and noninfectious diseases, due to a decrease in the level of specific resistance, low effectiveness of therapeutic and preventive measures and, as a result, will lead to a decrease in the quality of the resulting product. In view of this, studies aimed at studying the features of the course of radiation pathology in chickens are very relevant and will be taken into account when developing and applying radioprotective formulations.The study of the features of the course of acute radiation damage caused by uniform single irradiation at doses of 7 Gy; 9 Gy; 11 Gy and 13 Gy, at a power of 0.99 Gy/min, was carried out on Leningrad calico chickens. Resistance to ionizing radiation was assessed by generally accepted clinical and hematological methods. Pronounced changes in clinical manifestations and shifts in morphological parameters of peripheral blood were noted under the influence of gamma radiation. Thus, irradiation of chickens with doses of 11 Gy and 13 Gy caused the development of acute radiation damage of an extremely severe degree, which led to severe depression, refusal of feed, shortening the duration or absence of a latent period, against the background of severe leuko- and erythropenia. Irradiation with a dose of 9 Gy caused severe acute radiation damage characterized by adynamia, reduced feed intake, diarrhea with an admixture of blood. Leukopenia was noted in the blood, which by day 12 values were lower than before irradiation by 41.9% and erythropenia. During acute radiation damage in chickens, when irradiated at a dose of 7 Gy, the development of the initial, latent, peak and recovery period in the surviving individuals was clearly traced. The clinical manifestation was characterized by a complex of dyspeptic and neuromotor disorders, moderate leukopenia was noted in the blood. In all experimental chickens, a violation of egg production was noted, up to complete cessation against the background of irradiation at doses of 11 Gy and 13 Gy. It is concluded that uniform single irradiation of chickens in doses from 7 Gy to 13 Gy leads to acute radiation damage and negatively affects the productive qualities of poultry. In order to conduct the experiment on the principle of pairs of analogues, 5 groups of animals were formed, 10 chickens in each. Determination of the content of erythrocytes, leukocytes and platelets in the blood was determined by counting in the Goryaev chamber. External total single exposure to gamma radiation at doses of 7 Gy, 9 Gy, 11 Gy and 13 Gy led to the development of acute radiation exposure of medium, severe and extremely severe degrees, respectively.

GUI development for SSDL to calibrate photon measuring equipment

Current legislation mandates the inspection and calibration of operational survey radiation monitoring instruments used in nuclear medicine, radiotherapy departments, and other fields utilizing ionizing radiation sources. To comply with national and international radiation protection standards, Morocco's National Secondary Standard Dosimetry Laboratory provides reliable calibration results with high accuracy and covers various measurement ranges using attenuators provided by the automated Gamma G10 irradiator or validated beam qualities produced by the X-ray irradiator type X80–320 kV.This study aims to develop a digital graphical user interface using Python programming language, designed for calibrating radiation protection measuring instruments . The interface is intended to facilitate all operations and calculations related to determining calibration factors and measurement uncertainties in accordance with the ISO 4037 standard, ensuring minimal processing time and minimizing potential error sources . The interface enables calculations to be recorded, as well as the establishment and electronic archiving of the calibration certificate and the report in PDF format using the Hypertext Preprocessor FPDF library (PHP FPDF). With the development of this interface, multiple instruments can be processed per day with high accuracy, streamlining the calibration process and improving efficiency.•The importance of compliance with international standards to ensure the quality and reliability of measurements in radiation protection was examined.•Description of X-ray and Gamma-ray irradiators designed for the calibration of radiation protection measuring instruments within the Secondary Dosimetry Calibration Laboratory (SSDL) which is a member of the WHO/IAEA network within the National Center for Radiation Protection of Morocco•Graphical User Interface using python for the calibration of photon measurement instruments for radiation protection purposes was developped.

Риск заболеваний щитовидной железы, связанных с йодной недостаточностью, ликвидаторов последствий аварии на Чернобыльской АЭС ‒ работников предприятий атомной промышленности

Purpose: Assessment of thyroid disease risk associated with iodine deficiency, liquidators of the Chernobyl accident consequences, employees of nuclear industry enterprises depending on the doses of different types of exposure. Material and methods: The dose-risk assessment study included 12663 men, 1327 of whom had occupational exposure data. A Poisson’s process with intensity parameter was chosen as a statistical model of morbidity risk. The statistical package of epidemiological data analysis EPICURE was used for the estimation of excess relative risk (ERR) of thyroid diseases related to iodine deficiency. There was conducted a cohort epidemiological study of a group of liquidators who worked in the 30-km zone in 1986‒1990 over a period of more than thirty years depending on the dose received both during liquidation of the Chernobyl accident consequences and during professional work with radioactive substances (RS) and ionizing radiation sources (IRS). Results: As a result of the study direct estimates of radiogenic risk of thyroid diseases associated with iodine deficiency in the liquidators of the Chernobyl accident consequences were obtained for the first time using the data on doses of Chernobyl and the sum of these doses with the doses of occupational exposure. It is shown that the risk of disease per unit dose (ERR/Zv) for dose loads received both at liquidation of Chernobyl accident consequences and for total doses give different results. Conclusion: Assessment of the risk of thyroid diseases associated with iodine deficiency, liquidators of the Chernobyl NPP accident consequences and workers of nuclear industry enterprises, serviced by FMBA health care institutions of Russia using the doses of different types of exposure gives different results. Correct results of assessing the risk of radiation-related diseases can only be given by the register using the total radiation dose (occupational, accidental, medical, natural), as required by the directive documents.

РАДИАЦИОННЫЕ ИСТОЧНИКИ И ДОЗЫ ОБЛУЧЕНИЯ ПЕРСОНАЛА И ПАЦИЕНТОВ ПЭТ-ЦЕНТРА

Introduction 1. Emissions in cyclotron facility and their influence on staff 2. Radiation sources of radiochemical laboratory and radiation exposure of radiochemists 3. Ionizing radiation sources in PET diagnostics division and doses of medical staff 4. Doses of PET center patients Conclusion

ПРОГНОЗ РАДИАЦИОННЫХ РИСКОВ РАКА ЩИТОВИДНОЙ ЖЕЛЕЗЫ СРЕДИ НАСЕЛЕНИЯ РАЙОНОВ БРЯНСКОЙ ОБЛАСТИ, ЗАГРЯЗНЕННЫХ ВСЛЕДСТВИЕ АВАРИИ НА ЧЕРНОБЫЛЬСКОЙ АЭС, С УЧЕТОМ НЕОПРЕДЕЛЕННОСТЕЙ ОЦЕНОК МОДЕЛЕЙ РИСКА

Purpose: Forecasting the lifetime attributable radiation risk of incidence with malignant neoplasm (MN) of the thyroid gland and identifying groups of increased radiation risk (HR) for the population of the Bryansk region currently (at the beginning of 2023) living in six areas most contaminated with radionuclides after the accident at Chernobyl NPP, based on a conservative approach, taking into account dose uncertainty factors and parameters of mathematical risk models. Material and methods: The mathematical model of the radiation risk of thyroid cancer is the model recommended by the International Commission on Radiological Protection (ICRP). The uncertainty assessment of radiation risks was carried out by simulation modeling, i.e. by multiple calculation of random realizations of the risk using the normal or log-normal distribution of all parameters involved in the calculation of this risk. Based on a set of random realizations, 95 % confidence limits of risks were estimated. The Unified Federal Database of the National Radiation and Epidemiological Register (NRER) containing reconstructed absorbed doses in the thyroid gland in the population was used as the initial data for the calculation. Results: At the beginning of 2023, the group of 37–40-year-old women is characterized by the maximum radiation risks of thyroid cancer. According to conservative estimates (according to the upper 95 % confidence limits of radiation risk assessments), up to 19.9 % of people from this group may experience the development of radiation-induced thyroid cancer in the future, and for 37-year-old women this proportion can be up to 30.0 %. The greatest risk is predicted for people living in the Krasnogorsk district of the Bryansk region. Radiation-induced thyroid cancer can develop in 40.1 % of individuals from this group. Radiation risks of thyroid cancer in men are up to 10 times lower than in women. For 74.5 % of the population of the entire studied cohort, it is predicted that the maximum individual risk of 5.0×10-5, established by NRB-99/2009 for the population under normal operation of ionizing radiation sources, will be exceeded. Conclusions: At present (since 2023 and for life), the population of the most polluted districts of the Bryansk region continues to be at a high risk of developing radiation-induced thyroid cancers. Women at the age of 0–3 years at the time of exposure (in 1986) should be allocated to the maximum risk group. The results of this work can be used in the preparation of recommendations by health authorities to improve medical monitoring of exposed citizens.

Effects of ionizing radiation sources and dose levels on quality characteristics of meal ready to eat (Minced cow meat)

Effects of ionizing radiation sources and dose levels on quality characteristics of meal ready to eat (Minced cow meat)