Investigate Body Composition Research Articles

Body composition asymmetry between dominant and non-dominant arms in experienced overhead throwing sports athletes.

Overhead throwing can cause asymmetric physical characteristics induced by certain repeated asymmetric movements. Characterizing these physical properties could provide insights for health promotion, conditioning, and training planning. The status of asymmetric body composition and physical function in overhead throwing sports athletes remains unclear. The aim of this study was to investigate body composition asymmetries in experienced overhead throwing sports athletes. This study included 77 college students classified into three groups, overhead throw sports, non-overhead throw sports, and non-sports experience groups, based on past and current sports activities and years of experience. A body composition analyzer was used to measure body composition variables. The asymmetry in body composition variables between limbs was evaluated using the asymmetry index. Differences between groups were compared using one-way analysis of variance and post-hoc tests. The lean muscle mass asymmetry index of the arms in the overhead throw group was significantly higher than that in the other groups. The dominant arm lean muscle mass in the overhead throw group was significantly higher than that in the other groups. However, the non-dominant arm lean muscle mass in the overhead throw group was significantly higher than that in the non-sports experience group. Overhead throwing sports results in increased muscle mass in the dominant arm and produces asymmetry in muscle mass between the arms. This asymmetry may be induced by repeated and frequent asymmetrical motions. Our findings highlight the importance of characterizing the effect of sports activities on the athletes and may provide insights for conditioning regimens for them.

53 Associations between body composition, ClearCode34, and clinical outcomes in localized clear cell renal cell carcinoma

Abstract Background Emerging evidence suggests that pre-surgical body composition is a prognostic factor for cancer outcomes. Lower skeletal muscle quantity and radiodensity have been associated with renal cell carcinoma (RCC) outcomes in other studies, while reports of the relationship between visceral adipose tissue and RCC outcomes have been inconsistent. Mechanisms underlying these associations are unclear but may relate to tumor biology. We leveraged a large molecular epidemiology study of localized clear cell renal cell carcinoma (ccRCC) patients to examine how pre-surgical body composition features were associated with survival post-nephrectomy as well as ClearCode34 status, a previously validated prognostic gene expression signature. Methods The RESOLVE study at Memorial Sloan Kettering Cancer Center is a retrospective study of 1,239 patients with stage I-III ccRCC undergoing nephrectomy without systemic therapy. Pre-surgical CT scans at the third lumbar vertebrae were segmented for the cross-sectional areas and radiodensities of skeletal muscle, subcutaneous adipose and visceral adipose tissues using Automatica software. Formalin-fixed, paraffin-embedded tumor tissue samples were available for 929 patients, which were sent to the University of North Carolina at Chapel Hill and assayed for gene expression. RNA was extracted from these samples and analyzed using the Nanostring nCounter system on a custom panel of 356 genes, including the 34 genes used in the ClearCode34 assay. Of the 929 patients with tumor tissue available, gene expression data from 837 patients (90.1%) passed RNA extraction and data QC. Samples were classified into either ccA or ccB ClearCode34 classes using a reference data set and PAM (prediction analysis of microarrays) centroid-based classification. We estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for disease-free survival (DFS) within five years of diagnosis using Cox proportional hazards models for both body composition variables and ClearCode34 subtype. We also estimated odds ratios (ORs) and 95% CIs for associations between ClearCode34 subtype and body composition with logistic regression. All multivariable models were adjusted for age, sex, and all body composition variables. Results Of the 837 patients in our analytic sample, 219 (26%) had ccB tumors. Men, patients with high stage or grade tumors, and patients with chronic kidney disease prior to nephrectomy were more likely to present with ccB tumors. Lower skeletal muscle density (SMD) was significantly associated with lower five-year DFS [HR (95% CI) per 10 HU decrease in SMD: 1.7 (1.2, 2.3)]. While no other body composition features were significantly associated, we also observed non-significantly increased HRs for VATI and VATD [HR (95% CIs): 1.3 (0.8, 2.0) and 1.5 (0.9, 2.7), respectively]. ClearCode34 subtype was significantly associated with five-year DFS, where patients with ccB tumors had poorer DFS [HR (95% CI): 1.7 (1.1, 2.5)] compared to patients with ccA tumors. Notably, we observed no significant associations between any body composition feature and ClearCode34 in univariable analyses. However, in multivariable models that accounted for all body composition variables simultaneously as well as age and sex, lower SMD emerged as significantly associated with ccB subtype [OR (95% CI) per 10 HU decrease in SMD: 1.3 (1.0, 1.7)]. Conclusions Our findings suggest that the associations observed between body composition features and clinical outcomes in ccRCC may be related to tumor biology. Lower pre-surgical SMD, which may represent myosteatosis and metabolic dysregulation in ccRCC patients, was associated with both decreased five-year DFS and an increased likelihood of presenting with a more aggressive ccB tumor. Future studies should investigate body composition features related to ccRCC prognosis and additional markers of tumor biology, such as immune-related gene expression patterns, to extend these findings.

The Influence of Models of Different Structures of Strength Training Classes in Horting on the Indicators of Bioimpedansometry

Topicality. In the modern system of training in mixed martial arts, in particular in the sport of horticulture, the search for optimal models of training programs aimed at improving strength capabilities and body composition of athletes is actively investigated. The Purpose of the Research. To study the peculiarities of the influence of different models of strength training in horting on the indicators of the body composition of athletes.. Methods. 60 athletes who have been involved in horting for 3–4 years took part in the study. 3 research groups were formed. The representatives of the examined groups used experimental training models during 3 months of strength training. Using the non-invasive method of bioimpedance measurement during all stages of the study, the nature of changes in parameters of body composition indicators was assessed. The Results. It was established that only representatives of the 2nd group showed a positive increase in parameters of active cellular body mass (ACM, %) by 3,7 % (p<0,05) during the 3 months of the study compared to the initial data. A significant decrease in the parameters of this body composition indicator was found in the athletes of the other two groups. The greatest increase in BJM among the participants was found in athletes of group 3. At the same time, in representatives of group 1, the level of the studied indicator is almost half as low as compared to the results that were found in athletes of group 3 during the three months of the experiment. The greatest dynamics towards a decrease in the BM indicator (%) by 2,8 % (p<0,05), over the entire period of the study, is observed in athletes of group 1. At the same time, in the representatives of the other two groups, during the entire period of the experiment, we observe identical dynamics of the investigated body composition indicator, the level of which differs by only 0,7 % from the results demonstrated by the athletes of the 1st group. Findings. The use in the process of strength training in horting of variations of exercise complexes effective in strength fitness on simulators under the conditions of the principle of “premature fatigue” of agonist muscles due to exercises of an isolating nature, allows to maximally influence the parameters of body composition compared to the results that were found in other conditions of training activities.

Impact of sustained calorie restriction and weight cycling on body composition in high-fat diet-fed male and female C57BL/6J mice.

The objective of this study was to investigate body composition changes with weight cycling (WC) among adult C57BL/6J mice with diet-induced obesity. A total of 555 single-housed mice were fed a high-fat diet ad libitum (AL) from 8 to 43 weeks of age. The 200 heaviest mice of each sex were randomized to the following four groups: ever obese (EO, continued AL feeding); obese weight loser (OWL, calorie-restricted); obese weight loser moderate (OWLM, body weight halfway between EO and OWL); and WC (diet restricted to OWL followed by AL refeeding cycles). Body weight and composition data were collected. Linear regression was used to calculate residuals between predicted and observed fat mass. Linear mixed models were used to compare diet groups. Although weight loss and regain resulted in changes in body weight and composition, fat mass, body weight, and relative body fat were not significantly greater for the WC group compared with the EO group. During long-term calorie restriction, males (but not females) in the OWLM group remained relatively fatter than the EO group. WC did not increase body weight or relative fat mass for middle-aged, high-fat diet-fed adult mice. However, long-term moderate calorie restriction resulted in lower body weight but greater "relative" fat in male mice.

Associations between Geriatric Nutrition Risk Index, bone mineral density and body composition in type 2 diabetes patients.

Type 2 diabetes mellitus (T2DM), a fast-growing issue in public health, is one of the most common chronic metabolic disorders in older individuals. Osteoporosis and sarcopenia are highly prevalent in T2DM patients and may result in fractures and disabilities. In people with T2DM, the association between nutrition, sarcopenia, and osteoporosis has rarely been explored. To evaluate the connections among nutrition, bone mineral density (BMD) and body composition in patients with T2DM. We enrolled 689 patients with T2DM for this cross-sectional study. All patients underwent dual energy X-ray absorptiometry (DXA) examination and were categorized according to baseline Geriatric Nutritional Risk Index (GNRI) values calculated from serum albumin levels and body weight. The GNRI was used to evaluate nutritional status, and DXA was used to investigate BMD and body composition. Multivariate forward linear regression analysis was used to identify the factors associated with BMD and skeletal muscle mass index. Of the total patients, 394 were men and 295 were women. Compared with patients in tertile 1, those in tertile 3 who had a high GNRI tended to be younger and had lower HbA1c, higher BMD at all bone sites, and higher appendicular skeletal muscle index (ASMI). These important trends persisted even when the patients were divided into younger and older subgroups. The GNRI was positively related to ASMI (men: r = 0.644, P < 0.001; women: r = 0.649, P < 0.001), total body fat (men: r = 0.453, P < 0.001; women: r = 0.557, P < 0.001), BMD at all bone sites, lumbar spine (L1-L4) BMD (men: r = 0.110, P = 0.029; women: r = 0.256, P < 0.001), FN-BMD (men: r = 0.293, P < 0.001; women: r = 0.273, P < 0.001), and hip BMD (men: r = 0.358, P < 0.001; women: r = 0.377, P < 0.001). After adjustment for other clinical parameters, the GNRI was still significantly associated with BMD at the lumbar spine and femoral neck. Additionally, a low lean mass index and higher β-collagen special sequence were associated with low BMD at all bone sites. Age was negatively correlated with ASMI, whereas weight was positively correlated with ASMI. Poor nutrition, as indicated by a low GNRI, was associated with low levels of ASMI and BMD at all bone sites in T2DM patients. Using the GNRI to evaluate nutritional status and using DXA to investigate body composition in patients with T2DM is of value in assessing bone health and physical performance.

Body composition in early pubescent children with obesity: effects following 1 year of nonintervention.

Little is known about whether body composition changes differently between children with and without obesity following 1 year of nonintervention. Therefore, we investigated body composition in early pubescent children (8-12 yr) with and without obesity before and after a period of 1 year of nonintervention. Early pubescent children (8-12 yr; Tanner stage ≤ 3) with (body mass index, BMI ≥ 95th percentile) and without obesity (15th < BMI < 85th percentile) were recruited. At baseline, 88 children (n = 25 without obesity) completed dual-energy X-ray absorptiometry imaging (DXA) for body composition measurements [%body fat, fat mass, fat-free mass (FFM)]. One year later, 47 participants (n = 15 without obesity) returned for repeat testing. The children without obesity were older (11.0 ± 1.0 vs. 10.0 ± 1.2 yr; means ± SD) (P = 0.013). There was no group difference in height, and both groups increased in height similarly after 1 year (147.7 ± 8.9 to 154.5 ± 9.2 cm without vs. 145.6 ± 5.8 to 152.5 ± 5.9 cm with obesity) (P < 0.001). Weight was greater (P < 0.001) in children with obesity at baseline as was the increase in weight after 1 yr (9.25 vs. 5.82 kg) (interaction, P = 0.005). Fat mass increased by 4.4 kg in children with obesity and by 1.1 kg in children without obesity (interaction, P < 0.001). However, there was no difference in fat-free mass between those with and without obesity at baseline (29.9 ± 5.9 vs. 31.6 ± 4.8 kg) (P = 0.206) with both groups increasing similarly over 1 year (gain of 4.87 vs. 4.85 kg with and without obesity, respectively). Without intervention, the increase in fat mass is four times greater in children with obesity after 1 year as compared with children without obesity.NEW & NOTEWORTHY Little is known about changes in body composition in children with and without obesity following 1 year of nonintervention. We report that without intervention, fat mass gain is significantly greater in children with obesity after 1 year compared with those without obesity. Body mass index (BMI) and %body fat measurements after 1 year yielded no significant increase suggesting that BMI and %fat alone are not suitable measures for tracking changes in adiposity among children.

A ANTROPOMETRIA ESTÁ RELACIONADA ÀS HABILIDADES MOTORAS E FUTEBOLÍSTICAS EM JOGADORES SUB-13?

Introduction: Anthropometric profile of soccer players is known to have a strong effect on performance. However, there are limited studies in the literature as to which component of anthropometric profile has the greatest impact on performance among youth soccer players. Objectives: The aim of the study was to investigate body composition’s relationship with biomotor abilities and soccer specific skills in U13 soccer players. Methods: 84 soccer players participated to the study. Body composition parameters, subcutaneous fat tissue, vertical jump, horizontal jump, sprint performance, agility, balance and soccer skills of soccer players were evaluated. Results: Balance, sprint performance, agility and vertical and horizontal jump performances were negatively correlated with body fat percentage (p&lt;0.05). Agility, vertical and horizontal jumps were negatively correlated with body mass index (BMI) and waist circumference (p&lt;0.05). Sprint time was positively correlated with waist circumference (p&lt;0.05). Positive correlation was found between body fat percentage and dribbling time (p&lt;0.05). Conclusion: Waist circumference and body fat percentage may serve as a better predictor on performance compared to BMI and FFM in U13 soccer players. Therefore, coaches of youth soccer players should adopt a multidisciplinary approach and monitor body fat percentage to improve their players’ biomotor abilities and soccer skills.

Body composition, cardiorespiratory fitness, and neuromuscular adaptations induced by a home-based whole-body high intensity interval training

Background/objectiveBodyweight exercises performed at home could be a complementary approach to improve health-related fitness in people having little spare time and during stay-at-home periods. This study then investigated body composition, cardiorespiratory fitness, and neuromuscular adaptations to a home-based, video-directed, whole-body high-intensity interval training (WB-HIIT). MethodsFourteen subjects participated to an 8-week WB-HIIT (6 females, 23 ± 1 years) and fourteen were included in a non-exercise control group (CTL; 6 females, 24 ± 4 years). All took part to pre- and post-intervention assessments of body composition, peak oxygen uptake (VO2peak) and first ventilatory threshold (VT1; index of aerobic capacity), dynamic (leg press 3-repetition maximum) and isometric strength (knee extensors maximal isometric contractions with assessment of voluntary activation), and muscle endurance during an isometric submaximal contraction maintained till exhaustion. WB-HIIT consisted in 30-s all-out whole-body exercises interspaced with 30 s of active recovery. Training sessions were performed at home by means of videos with demonstration of exercises. Heart rate was monitored during sessions. ResultsWB-HIIT increased VO2peak (5%), VT1 (20%), leg lean mass (3%), dynamic (13%) and isometric strength (6%), and muscle endurance (28%; p < 0.05), while they did not improve in CTL. VO2peak increase was correlated (r = 0.56; p < 0.05) with the time spent above 80% of maximal heart rate during training sessions. Isometric strength increase was correlated with change in voluntary activation (r = 0.74; p < 0.01). ConclusionThe home-based WB-HIIT induced concomitant cardiorespiratory fitness and neuromuscular improvements. The predominant effect was observed for aerobic capacity and muscle endurance which could improve exercise tolerance and reduce fatigability.

The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study

BackgroundStudies focusing on the relationships of adiposity and body shape indices with reproductive factors have reported conflicting results. This study aimed to investigate the influence of reproductive factors on adiposity and body shape indices changes overtime.Materials and methodsIn this community-based prospective study, 1636 postmenopausal women were selected from Tehran Lipid and Glucose Study (TLGS). The unadjusted and adjusted Generalized Estimating Equation models (GEE) were applied to investigate secular longitudinal trends of adiposity and body shape indices.ResultsAccording to the adjusted GEE models, mean changes in body mass index (BMI) in women with early menarche was 1.18 kg/m2 higher than those with normal menarche age (P = 0.030). Moreover, the mean changes in BMI overtime were 0.11 kg/m2 higher in women with premature/early menopausal age than those with normal menopausal age (P = 0.012). Mean changes of waist circumference (WC) in women with late menopause were 2.27 cm higher than those with normal menopausal age (P = 0.036). We also observed higher mean changes in a body shape index (ABSI) in women with late menopause (P = 0.037), compared to those with normal menopausal age. We found a marginal effect of parity on BMI and WC as well.ConclusionsThis study demonstrated higher BMI in females with earlier menarche age. We also showed higher values of BMI overtime in women with premature/ early menopause, whereas women with late menopausal age had higher WC and ABSI values. However, more longitudinal studies investigating body composition indices by adjusting all potential confounders are still required to confirm our study findings.

Application of bioelectrical impedance in newborns: an integrative review.

the objective of this study was to identify the use of bioelectrical impedance in newborns (NB), as this is an easy-to-apply and non-invasive method of measurement that can be used for distinguishing fat-free mass (FFM), fat mass (FM), and total body water (TBW). this was an integrative review of the literature using the PUBMED/MEDLINE, EMBASE, Web of Science, and Virtual Health Library databases to search for original articles between 2010-2020. A total of 900 articles were retrieved; after checking for duplicity and applying the eligibility criteria, 9 were further analyzed. about the results, five studies used single frequency bioimpedance, with a specific population of neonates, preterm and/or full term, and different clinical conditions. Resistance was the most studied bioelectric indicator, the phase angle is little explored, and four studies investigated body composition (FFM, FM and TBW). Studies found that preterm newborns had lower amounts of TBW, FFM, and FM than term newborns, and there were differences in body composition between sex. The phase angle was lower for preterm newborns and fed babies with high protein formulas had increases in the FFM. there is a need for multicenter studies to define standardized methods to be used with this public.

Body Composition and Fitness Characteristics of Firefighters Participating in a Health and Wellness Program: Relationships and Descriptive Data.

This study investigated body composition and fitness test relationships from firefighters participating in a health and wellness program and categorized firefighters according to population norms relative to sex and age. Data from 270 firefighters (men = 258, women = 12) were analyzed, including body composition (body mass index [BMI], body fat percentage [BF%], waist circumference [WC], waist-to-hip ratio) and fitness (sit-and-reach, grip strength, leg press, crunches, push-ups, maximal aerobic capacity [V̇O2max]) tests. Mann-Whitney U-test analysis (p < 0.05) showed that male firefighters had a greater WC, WHR, grip strength and leg press. Female firefighters had a greater BF% and better sit-and-reach. Partial correlations controlling for sex indicated 22/24 correlations between body composition and fitness were significant (r = -0.143--0.640). ~52% of firefighters were overweight, and 25% were Obesity Class I-III. ~76% had an increased risk of cardiovascular disease (CVD) considering BMI and WC. ~22% were fatter than average-to-overfat considering BF%. Most firefighters (73-94%) were good-to-excellent in sit-and-reach, grip strength, and push-ups; average-to-well above average in crunches; average-to-above average in leg press; and had good-to-superior V̇O2max. Although most firefighters had better fitness compared to the general population, many had increased CVD risk. The data highlighted the need for comprehensive approaches to improving firefighter health and decreasing CVD risk.

Body composition does not influence conditioned pain modulation and exercise-induced hyperalgesia in healthy males and females.

Obese individuals report a higher susceptibility to chronic pain. Females are more likely to have chronic pain and excess adipose tissue. Chronic pain is associated with dysfunctional pain-modulatory mechanisms. Body composition differences may be associated with pain modulation differences in males and females. The purpose of this study was to investigate body composition (lean vs fat mass) differences and pain-modulatory functioning in healthy males and females. Pressure pain thresholds (PPT) of 96 participants (47 M; 49F) were assessed in both arms and legs before and after a double-footed ice bath (2°C) for 1 min and an isometric knee extension, time to failure task. The difference between post- and pre-measures was defined as conditioned pain-modulatory (CPM) response (ice bath) and exercise-induced hypoalgesia (EIH) response. Whole-body and site-specific fat and lean tissue were assessed via the DXA scan. Sex differences were found in whole-body lean mass (61.5 ± 6.7kg vs 41.2 ± 5.4kg; p < 0.001) but not fat mass amount (17.2 ± 10.5kg vs 21.0 ± 9.7kg; p=0.068). No effect of sex was found between limb CPM (p=0.237) and limb EIH (p=0.512). When controlling for lean mass, there was no significant effect of sex on CPM (p=0.732) or EIH (p=0.474) response. Similar findings were found for fat mass. The lack of difference suggests that males and females have similar modulatory functioning. It appears that in healthy adults free from chronic pain, neither fat mass nor lean mass has an influence on endogenous pain-modulatory function. Men and women exhibited similar CPM and EIH despite marked differences in body composition. Our findings suggest whole-body and limb-specific lean tissue mass and fat mass do not influence CPM and EIH in adults without chronic pain.

Body Composition Asymmetries in University Ice Hockey Players and Their Implications for Lower Back Pain and Leg Injury.

Resta, T, Frenette, S, Rizk, A, and Fortin, M. Body composition asymmetries in university ice hockey players and their implications for lower back pain and leg injury. J Strength Cond Res 36(10): 2830-2836, 2022-Right to left asymmetries in body composition have been examined across many sports, suggesting possible implications for lower back pain (LBP) and decreased level of performance. However, we are not aware of any study that has examined the presence and implications of morphological asymmetries in ice hockey players. The purpose of this study was to (a) investigate body composition asymmetries in female and male university-level ice hockey players and (b) examine whether the degree of body composition asymmetry is associated with the history of LBP and lower-limb injury (LLI). A total of 32 players (female = 18, male = 14) were included in this cross-sectional study (e.g., university research center setting). Dual-energy X-ray absorptiometry (DEXA) was used to acquire body composition measurements. The parameters of interest included bone mass, lean body mass, and fat mass, for the right and left sides and body segments (e.g., arm, leg, trunk, and total), separately. The history of LBP and LLI was obtained using a self-reported demographic questionnaire. The statistical significance for the study was set at p < 0.05. Our findings revealed significant side-to-side asymmetry in arm and total bone mass in females, with higher values on the right side. Both males and females also had significantly greater trunk lean body mass on the left side. With the exception of greater arm bone mass asymmetry being associated with LBP in the past 3 months, there was no other significant association between the degree of asymmetry with LBP and LLI. This study provides novel data regarding the presence of asymmetry in body composition in university-level ice hockey players. Monitoring body composition in athletes provides information that can be used by athletic trainers and strength and conditioning coaches to develop injury prevention, performance optimization, and targeted rehabilitation programs.

MRI characterization of skeletal muscle size and fatty infiltration in long-term trained and untrained individuals.

This study investigated body composition measures in highly trained and untrained individuals using whole‐body magnetic resonance imaging (MRI). Additionally, correlations between these measures and skeletal muscle gene expression were performed. Thirty‐six individuals were included: endurance‐trained males (ME, n = 8) and females (FE, n = 7), strength‐trained males (MS, n = 7), and untrained control males (MC, n = 8) and females (FC, n = 6). MRI scans were performed, and resting M. vastus lateralis (VL) biopsies were subjected to RNA sequencing. Liver fat fraction, visceral adipose tissue volume (VAT), total body fat, and total lean tissue were measured from MRI data. Additionally, cross‐sectional area (CSA) and fat signal fraction (FSF) were calculated from Mm. pectoralis, M. erector spinae and M. multifidus combined, Mm. quadriceps, and Mm. triceps surae (TS). Liver fat fraction, VAT, and total body fat relative to body weight were lower in ME and FE compared with corresponding controls. MS had a larger CSA across all four muscle groups and lower FSF in all muscles apart from TS compared with MC. ME had a lower FSF across all muscle groups and a larger CSA in all muscles except TS than MC. FE athletes showed a higher CSA in Mm. pectoralis and Mm. quadriceps and a lower CSA in TS than FC with no CSA differences found in the back muscles investigated. Surprisingly, the only difference in FSF between FE and FC was found in Mm. pectoralis. Lastly, correlations between VL gene expression and VL CSA as well as FSF showed that genes positively correlated with CSA revealed an enrichment of the oxidative phosphorylation and thermogenesis pathways, while the genes positively correlated with FSF showed significant enrichment of the spliceosome pathway. Although limited differences were found with training in females, our study suggests that both regular endurance and resistance training are useful in maintaining muscle mass, reducing adipose tissue deposits, and reducing muscle fat content in males.

Clinical impact of body composition on postoperative outcomes during neoadjuvant chemoradiation therapy for distal bile duct cancer.

Body composition changes during neoadjuvant therapy and their clinical significance have not been clarified. The present study aimed to investigate body composition changes during neoadjuvant chemoradiation therapy (NACRT) in patients with distal bile duct cancer and the clinical impact on postoperative complications and the prognosis. A total of 16 patients with distal bile duct cancer who underwent curative resection after NACRT were retrospectively evaluated. The area of skeletal muscle, visceral fat and subcutaneous fat on computed tomography and immunological and nutritional indices were assessed before and after NACRT. All 16 patients completed NACRT followed by pancreaticoduodenectomy without mortality. There was no significant change in the skeletal muscle mass index (SMI) during NACRT. Of the 16 patients, nine (56%) were defined as sarcopenic before NACRT, and eight (50%) met the criteria for sarcopenic after NACRT. The SMI and total fat area were significantly associated with postoperative pancreatic fistula (POPF) (P=0.019 and P=0.007, respectively). The patients with sarcopenia had a shorter disease-free survival time and overall survival time in comparison to patients without sarcopenia (P=0.025 and P=0.115, respectively). In conclusion, NACRT for distal bile duct cancer did not significantly affect the body composition, or the immunological or nutritional indices. Sarcopenia after NACRT was significantly associated with early recurrence in patients with distal bile duct cancer who received NACRT.

Nutritional Intake and Biomarker Status in Strict Raw Food Eaters.

Following a strict raw food diet (primarily based on fresh fruit and raw vegetables, waiving any consumption of heated or processed food) has the risk of undersupply of energy and certain macro- and micronutrients. In this cross-sectional study, we compared 16 non-smoking strict raw food eaters (5 women and 11 men, age 44.6 ± 12.3 years, duration of following the diet 11.6 ± 10.8 years) with the non-smoking participants (32 vegans, 27 omnivores) of the “Risk and Benefits of a Vegan Diet” (RBVD) study. We investigated body composition, dietary intake from 3-day weighed food records, and relevant fasting blood and serum parameters. Food choice and dietary behavior were very heterogenic in raw food eaters. They had lower mean values of BMI and percentage of body fat than the respective RBVD participants. The same holds true for energy supply and intakes of protein, carbohydrate, calcium and iodine. Serum levels revealed lower levels of HDL cholesterol, triglycerides, zinc, and vitamin D3. The raw food eaters with (n = 9) and without (n = 7) supplementation of vitamin B12 had median vitamin B12 levels of 399 and 152 ng/L, respectively. Accordingly, eight raw food eaters (50%) had homocysteine levels above 12 µmol/L. The study allows a close look at strict raw food eaters with respect to possible dietary deficiencies, but also provides insights into motivations and daily life.

복합 운동 프로그램이 성인의 simple NAFLD score에 미치는 영향

The purpose of this study was to identify 8 weeks combined exercise training for simple NAFLD score in adults and to investigate the correlation between simple NAFLD score and body composition, health and exercise related fitness, total cholesterol and blood glucose. Participant in this study divided into two groups, exercise group and control group. Subjects participating in this experiment were divided into two groups, and all subjects investigated body composition, health-related and exercise-related fitness level, total cholesterol and blood glucose before and after the experiment. A paired-samples t-test and Pearson

Skeletal muscle loss and body composition in progressive supranuclear palsy: A retrospective cross-sectional study.

Skeletal muscle mass loss has been associated with decreased physical performance; however, the body composition characteristics in progressive supranuclear palsy (PSP) are not well understood. We investigated body composition parameters, focusing on skeletal muscle mass, in patients with PSP and compared them with those of healthy older adults. This retrospective cross-sectional study included 39 patients with PSP and 30 healthy older adults (control group). Using a multi-frequency bioelectrical impedance analysis, we measured the skeletal mass index (SMI), basal metabolism, extracellular water/total body water ratio (ECW/TBW), and body fat percentage and examined the relationship between SMI and age, body mass index (BMI) and other body composition parameters. The PSP group had a higher rate of low muscle mass (56.4%) than the control group (10.0%), although the ages and BMIs were similar. The leg SMI was lower for the PSP group, while the ECW/TBW was higher for the PSP group. The basal metabolism was lower for the PSP group than for the controls but only in the women. The basal metabolism and BMI showed a significant correlation with SMI in the PSP group. There was a significant correlation between SMI and age, ECW/TBW, and body fat percentage in the PSP group but only in the women. This study is the first to show that a high proportion of patients with PSP have low muscle mass. We showed differences in terms of sex in muscle mass loss in women with PSP, which was associated with inactivity and aging.

Physiological Effects of Intermittent Passive Exposure to Hypobaric Hypoxia and Cold in Rats.

The benefits of intermittent hypobaric hypoxia (IHH) exposure for health and its potential use as a training tool are well-documented. However, since hypobaric hypoxia and cold are environmental factors always strongly associated in the biosphere, additive or synergistic adaptations could have evolved in animals’ genomes. For that reason, the aim of the present study was to investigate body composition and hematological and muscle morphofunctional responses to simultaneous intermittent exposure to hypoxia and cold. Adult male rats were randomly divided into four groups: (1) control, maintained in normoxia at 25°C (CTRL); (2) IHH exposed 4 h/day at 4,500 m (HYPO); (3) intermittent cold exposed 4 h/day at 4°C (COLD); and (4) simultaneously cold and hypoxia exposed (COHY). At the end of 9 and 21 days of exposure, blood was withdrawn and gastrocnemius (GAS) and tibialis anterior muscles, perigonadal and brown adipose tissue, diaphragm, and heart were excised. GAS transversal sections were stained for myofibrillar ATPase and succinate dehydrogenase for fiber typing and for endothelial ATPase to assess capillarization. Hypoxia-inducible factor 1α (HIF-1α), vascular endothelial growth factor (VEGF), and glucose transporter 1 (GLUT1) from GAS samples were semi-quantified by Western blotting. COLD and HYPO underwent physiological adjustments such as higher brown adipose tissue weight and increase in blood-related oxygen transport parameters, while avoiding some negative effects of chronic exposure to cold and hypoxia, such as body weight and muscle mass loss. COHY presented an additive erythropoietic response and was prevented from right ventricle hypertrophy. Intermittent cold exposure induced muscle angiogenesis, and IHH seems to indicate better muscle oxygenation through fiber area reduction.

Thermal optimum for mass production of the live feed organism Enchytraeus albidus.

Live feed organisms are essential for the larval stages of many fish species grown in aquaculture, and juvenile fish reared on live feeds often exhibit higher survival and growth than those reared on formulated feed. The terrestrial enchytraeid (white worm), Enchytraeus albidus, has potential as a sustainable source of live feed because it can easily be mass produced, feeds on a wide range of organic waste materials and has high contents of protein and long-chain poly-unsaturated fatty acids. In the present study, we observed the effect of temperature on population growth over five months using soil microcosms. At the outset, each microcosm was supplied with approximately the same number of cocoons. Hatched enchytraeids were given rolled oats ad libitum as feed. We followed the population growth at seven temperatures in the range of 4-25°C and investigated body composition in order to find optimal temperature for mass production. Results showed that E. albidus has a broad thermal optimum range and displays almost similar biomass production in the range of 15-22°C with specific growth rates between 6.5 and 6.8%. In this temperature range, protein contents were 40-45%, glycogen contents 20-25% and total fatty acid contents 15-20% of dry weight. The temperature had a highly significant effect on fatty acid composition. In particular, the abundance of omega-3 fatty acids (18:3ω3 and 20:5ω3) was largest at low temperature. For what concerns achievable density of worms in mass cultures, our results surpassed previous results and showed that densities close to 100gL-1 substrate are realistic. Maximum production of biomass can likely reach 80g live worms L-1 month-1at temperatures between 15 and 22°C.