Congenital heart disease due to ventricular septal defect is a serious congenital defect, most of the time, and although exceptional, it can also be acquired after rupture of the interventricular septum in an acute myocardial infarction. The objective was to manage the nursing care process in a post-operative preschool patient. The study had a qualitative approach, single case type, the methodology was the nursing care process, the assessment stage was carried out through the assessment framework of Maryori Gordon's 11 functional patterns, the diagnostic stage was developed based on To taxonomy II of NANDA I, nursing diagnoses were identified, prioritizing three of them: Decreased cardiac output, ineffective tissue perfusion and dysfunctional ventilatory response to weaning according to the SSPFR format (signs and symptoms, problem, related factor/risk factor/ associated to); Likewise, the planning stage was carried out taking into account the NOC Taxonomy, NIC, in the execution stage the care was administered and the evaluation was given by the difference in final and baseline scores respectively. A change score of +1, 0, +1 was obtained in the results. In conclusion, the nursing care process for the patient was managed that allowed quality care to be provided to the patient