Objective:To evaluate the clinical indication, technique, effect and cautions of intranasal endoscopic surgery for nasopharyngeal tumor. Methods:Between December 2016 and April 2021, 31 patients who received endoscopic nasopharyngectomy for nasopharyngeal tumors were analyzed retrospectively, 8 benign and 23 malignant cases were included. 8 benign cases included 7 cases with nasopharyngeal fiber hemangioma and 1 case with polymorphic adenoma. Twenty-three malignant cases included 12 cases with recurrent nasopharyngeal carcinoma after chemoradiotherapy and 11 cases with various types of malignancies. All patients underwent endoscopic resection of nasopharyngeal tumors through bilateral transnasal approach. Results:Total resection of the tumor was achieved for all cases without severe surgical complications. 8 cases with benign tumors, with following-up of 5-49 months, showed no recurrence. 23 cases with malignant tumors, with following-up of 6-58 months, 22 cases show no recurrence, 1 recurent nasopharyngeal osteosarcoma, curved after another operation and assisted with chemotherapy, 1 case with nasopharyngeal carcinoma survived with disease after two endoscopic operations. Conclusion:Nasopharyngeal tumor could be completely resected with endonasal endoscopic surgery according to the anatomic structure. Surgery should provide a panoramic view on nasopharyngeal cavity and tumors, protect important structures.