Intracerebral Brain Hemorrhage Research Articles

Estimation of Linoleic Acid in Flax Seed Oil Formulation using a Validated High-performance Thin-layer Chromatograph Method

Linoleic acid, an omega-6 fatty acid present widely in plant seeds and one of the major components among the fatty acids in Linum Usitatissimum L., commonly called as flax seed and represents the content of 12–19% out of the total lipids in flax seed. This work attempted to quantify the Linoleic acid from flax seed oil using the high-performance thin layer chromatography (HPTLC) method with mobile phase, methanol: toluene: formic acid (3:7:1 v/v), and the wavelength used is 254 nm. The method gave a sharp, symmetrical peak at Rf value 0.63 ± 0.02. The method was validated using intracerebral brain hemorrhage (ICH) guidelines and applied to the assay of marketed capsules of flaxseed. It is confirmed that the reported method can help analyze flax seed oil in different dosage forms, along with cosmetic products containing linoleic acid-rich oils.

Effect of Intravenous Tranexamic Acid on Intracerebral Brain Hemorrhage in Traumatic Brain Injury.

To determine the effect of Intravenous Tranexamic Acid (TXA) on traumatic intracerebral hemorrhage. A total of 94 cases of TBI with intracerebral hemorrhage, admitted to the emergency department who did not need surgical intervention based on a primary brain spiral computed tomography (CT) scan, were randomly assigned into two groups of 47 patients. In the intervention group, intravenous TXA was administered as one gram of bolus and one gram every 6 hours for 48 hours, and in the control group, the placebo was administered in the same way. After 6, 24, and 48 hours all the cases underwent a brain CT scan. Scans were examined for the size and diameter of hematoma and the midline shift. The information regarding the level of consciousness, hematoma volume, and diameter on CT scan were recorded on arrival and 48 hours later. Statistical results depict that while there was no considerable difference in the demographic aspect of the two groups, the volume and diameter of hematoma and the midline shift in the first CT scans and also their level of consciousness, the diameter and volume of hematoma and also the amount of hematoma expansion in follow up are significantly different in the two groups. The present study showed that the prescription of TXA would reduce the amount of hematoma expansion in traumatic intracerebral hemorrhage, and that medication can be introduced to reduce morbidity and complications.

Spontaneous Intracerebral Brain Hemorrhage Localized in the Basal Ganglia

Spontaneous Intracerebral Brain Hemorrhage Localized in the Basal Ganglia

The natural course of spontaneous intracerebral brain hemorrhage localized in the basal ganglia of the brain: The analysis of a series of 39 patients

The study included 39 patients treated in a Special hospital for the prevention and treatment of cerebrovascular diseases ? Sveti Sava? in Belgrade in the period from October 2010 to January 2012. The criteria for inclusion in the study is the moment of diagnosis of spontaneous intracerebral hemorrhage (ICH) in the basal ganglia of the brain (BG). The results: we analyzed 25 male patients and 14 female patients, aged 54 years to 95 years. In deceased group - 22 (56.4%), 20 (90.9%) were the age group 60 to 80 years., GCS: 3-5 -12 patients (54.5%) died, GCS 6 -8 -10 patients (45.5%), 20 patients (90.9%) also had intracerebral and intraventricular hemorrhage complicated by acute hydrocephalus. Conclusion: predisposing factors for mortality within one year in patients with spontaneous intracerebral hemorrhage in the basal ganglia of the brain are: males older than 60 years, unregulated hypertension and penetration of blood in the chamber system.

3-D image analysis of intra-cerebral brain hemorrhage from digitized CT films

A new 3-D technique for the segmentation and quantification of human spontaneous intra-cerebral brain hemorrhage (ICH) is presented in this paper. The algorithm for ICH primary region segmentation uses the spatially weighted K-means histogram-based clustering algorithm. The ICH edema region segmentation algorithm employs an iterative morphological processing of the ICH brain data. A volume rendering technique is used for the effective 3-D visualization of ICH segmented regions. A computer program is developed for use in the human spontaneous ICH study involving a large number of patients. Experimental measurements and visualization results are presented which were computed on real ICH patient brain data.