Intimal Angiosarcoma Research Articles

Intimal angiosarcoma of the thoracic aorta diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration: a case report

BackgroundPrimary malignant tumors of the aorta are extremely rare. They are frequently located in the abdominal aorta, followed by the thoracic aorta. Sarcomas are the most common histological type. These tumors originate from the middle or intimal layer, the latter being the most common. Symptoms and radiological findings are generally nonspecific. Since their growth is endovascular, embolic phenomena can occur leading to occlusive signs and symptoms.Case presentationWe describe the case of a 75-year-old Hispanic man, a former tobacco smoker, with a history of pain and epigastric tenderness, dysphagia, and weight loss of approximately 6 kg. A thorax computed tomography scan showed a mass within the posterior mediastinum with poorly defined borders and heterogeneous density, located between thoracic vertebra 5–8, with a size of 78 × 53 × 76 mm, with left main bronchus compression. Endobronchial ultrasound-guided transbronchial needle aspiration was performed; it found an extrinsic posterior compression of the left main bronchus with no endobronchial injury. An intimal angiosarcoma of the thoracic aorta was diagnosed.ConclusionTumors of the aorta are rare and difficult to diagnose; they are a challenge during the diagnosis, since they usually require open surgical procedures. Endobronchial ultrasound-guided transbronchial needle aspiration associated with rapid on-site examination offered, in this case, the possibility of a successful diagnosis, avoiding major procedures. This is the first case reported in the literature of an intimal angiosarcoma of the thoracic aorta diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration.

Intimal Angiosarcoma of the Aorta: Single Case Report and Effective Surgical Management

Primary malignant tumors of the aorta (PMTAs) are not only extremely rare, but also exhibit enormous histological heterogeneity. We present the first recorded case of a female patient with intimal angiosarcoma of the aortic arch and descending thoracic aorta in China, along with the clinical presentation, histopathologic diagnosis, and surgical excision of the lesion. We propose surgery as a viable curative approach to angiosarcomas of intimal origin. J Curr Surg. 2017;7(4):64-68 doi: https://doi.org/10.14740/jcs332w

Acute Arterial Occlusive Disease caused by An Intimal Angiosarcoma

Acute Arterial Occlusive Disease caused by An Intimal Angiosarcoma

Intimal Angiosarcoma of the Carotid Artery

Introduction Intimal angiosarcoma of the carotid artery is extremely rare. Report We report the case of a 77-year-old-man who presented with a 2-month history of a right-lateral cervical mass and paralysis of cranial nerves with a chronic occlusion of the carotid artery. The patient underwent en-bloc tumour resection. Diagnosis was made using immunohistochemical testing: tumour cells were positive for CD31, vimentin, and CD68 (in this case), and negative for CD34 and cytokeratin. Discussion Even after successful removal of the tumour and adjuvant therapy, prognosis is poor.

Pseudocoarctation of the Aorta Secondary to Aortic Intimal Sarcoma

We describe a case of a 66-year-old woman who presented with upper extremity hypertension and a pseudocoarctation-like picture secondary to an aortic arch intimal sarcoma.

Intimal angiosarcoma presenting with common femoral artery aneurysm

Intimal angiosarcoma is a rare malignant vascular tumor with an aggressive natural history. Presenting symptoms vary according to the location of the lesion, but symptoms are typically due to intravascular obstruction or embolization. We present a case of an intimal angiosarcoma presenting with a common femoral artery aneurysm.

Postoperative outcomes in intimal aortic angiosarcoma: A case report and review of the literature

Intimal angiosarcoma is a most unexpected cause of aortic occlusion. We present the case of a 74-year-old woman with intimal angiosarcoma that manifested with the triad of congestive heart failure, acute renal failure, and abdominal angina. A review of the literature and discussion of postoperative outcomes follows.

Femoral artery angiosarcoma presenting with distal embolization: Report of a case

Angiosarcoma of the femoral artery is an extremely rare malignant vascular tumor. The initial diagnosis is difficult to establish and distal metastasis can sometimes be the only presenting symptom. In this paper, we report the case of a 54-year-old man who presented with multiple painful necrotic lesions over the right foot secondary to an intimal angiosarcoma of the right common femoral artery.

Primary aortic intimal sarcoma

Aortic intimal angiosarcoma is extremely rare, and the prognosis of patients with a tumor is unfavorable even if they have undergone surgery. We treated a patient with primary intimal angiosarcoma of the aortic arch who underwent an operation. The tumor originated from the inner wall of the aortic arch on the lesser curve. In order to remove the tumor completely, the entire aortic arch from the ascending to the middle of descending aorta was resected through an L-shape skin incision. On histologic examination, an undifferentiated intimal sarcoma was diagnosed. It grew into the aortic lumen while spreading along the aortic intima, focally infiltrating the media. The postoperative course was uneventful. Postoperative CT performed at 6, 12 and 18 months after surgery showed no local recurrence or metastasis. According to some reports endoarterectomy has been performed to treat this type of tumor, since the malignant cells are thought to be limited to the luminal surface. However, we favor aortic resections and graft interpositions rather than an endoarterectomy because the tumor could have invaded the media.

術後に多発性転移を生じた血管肉腫による遠位弓部大動脈解離の 1 例

術後に多発性転移を生じた血管肉腫による遠位弓部大動脈解離の 1 例

Intimal angiosarcoma of the aorta: Report of a case and review of the literature

Although extremely rare, the group of primary malignant tumors of the aorta (PMTA) exhibits enormous histologic heterogeneity. In most cases, diagnosis is established late in the course of the disease; the median survival time is only a few months. We present the case of a 75-year-old patient with an intimal angiosarcoma of the infrarenal abdominal aorta and discuss the clinical presentation, histopathologic diagnosis, and classification of primary aortic sarcomas. A critical review of the diagnostic and therapeutic management in this case revealed that the atypical aortic thrombus should have prompted a comprehensive preoperative diagnostic work-up, specifically with magnetic resonance tomography of the aorta and bone scintigraphy.