Intestinal Intussusception Research Articles

Endoscopic resection of a juvenile jejunum polyp which caused recurrent intestinal bleeding in a 12-month-old child: clinical observation

BACKGROUND: To verify a source of obscure gastrointestinal bleeding leading to iron deficiency anemia is a challenging diagnostic problem. Intestinal polyps can be one of such sources. Sporadic juvenile intestinal polyps are extremely rare at the first year of life. The authors present a clinical case which demonstrates endoscopic diagnostics and resection of a jejunum polyp in a 12-month-old child weighing 6.3 kg. We did not find similar publications in literature. CLINICAL CASE DESCRIPTION: A 12-month-old boy was admitted to our clinic with long-lasting complaints of dark stool and iron deficiency anemia. For the first time, gastrointestinal bleeding symptoms appeared at the age of one month. The child was repeatedly examined, but gastrointestinal bleeding source was not found. The child was prescribed symptomatic therapy for iron deficiency anemia including red blood cell transfusion. At current hospitalization in our clinic an intestinal polyp and transient small intestinal intussusception were suspected at ultrasound examination. The child underwent esophagogastroduodenoscopy, video capsule endoscopy, colonoscopy, laparoscopy. But the source of the bleeding was not found. During the repeated enteroscopy at 40 cm distally to the pylorus a sporadic juvenile jejunum polyp 17×15 mm was found and resected. The postoperative period was uneventful. In 1 month, there were no complaints as for the catamnesis, the child's stool had the usual characteristics, the indicators of "red blood" corresponded to the age norm. CONCLUSION: A sporadic juvenile jejunal polyp may be a cause of obscure recurrent intestinal bleeding in children. Modern intraluminal endoscopy allows not only to put diagnosis, but also to perform a minimally invasive surgical intervention.

065. Ileoileal Small Bowel Intussusception in Adult

Background: Intestinal Intussusception is invagination of a proximal segment of the gastrointestinal tract into the distal. In adults, ileoileal intussusception is a rare case and diagnostically challenging. We present four cases of ileoileal small bowel intussusception in adults. Case: a 19-year-old man with complaint of abdominal pain. An exploratory laparotomy was performed, an ileoileal invagination was found. Second case : a 29-year-old woman with complaint of not being able to defecate or flatus. An ileal dilatation up to 240 cm from the ligament of treitz and ileoileal invagination with an ileal tumor was found in exploratory laparotomy. Third case : a 51-year-old man with complaint of difficulty defecating since 1 day before admission. A 30 cm long ileoileal invagination and tumor in the invaginated ileum was found. Fourth case : a 77-year-old man with a difficulty in defecating. A dilatation of the bowel starting from jejunum-ileum and a 20 cm long invagination was found. Conclusion: Clinical presentation of bowel obstruction is helpful to diagnose adult ileoileal small bowel intussusception. The mainstay of treatment is surgical intervention.

Intestinal intussusception: Uncommon occurrence in a 25-year-old female: A case report

Intestinal intussusception: Uncommon occurrence in a 25-year-old female: A case report

Malignancy predictors and treatment strategies for adult intestinal intussusception.

Intussusception in adult patients is a rare medical finding, which is accompanied by an underlying tumor in some cases. However, no accepted method has been established to identify patients at risk for tumor-related intussusception. This study aimed to identify imaging features as predictors for tumor-related intussusception.CT images of patients with confirmed intussusception were retrospectively acquired between 01/2008 and 12/2022. Available follow-up images and medical health records were evaluated to identify various imaging features, the cause of intussusception, and treatment strategies. Imaging interpretation was conducted by two blinded radiologists. A third radiologist was consulted in cases of disagreement.A total of 71 consecutive patients were included in this study (42 males, 29 females) with a median age of 56 years (interquartile range: 40.5-73.8 years). Enteroenteric intussusceptions in the small bowel were the most common type observed in adult patients. In contrast, colocolic intussusception was more frequently associated with malignancy, and this association was statistically significant (p < 0.05). Among the malignant tumors, adenocarcinoma was the most common, followed by metastases and lymphoma. Additionally, bowel obstruction and wall thickening were significantly correlated with malignancy (p < 0.05). The high negative predictive values (NPVs) and high specificities for ileus (NPV 88.5%, specificity 82.1%), bowel wall thickening (NPV 90.9%, specificity 71.4%), and acute abdomen (NPV 84.6%, specificity 78.8%) suggest that the absence of these features strongly predicts a low probability of malignancy in cases of adult intussusception.Active surveillance with follow-up exams is suitable for asymptomatic and transient intussusception when imaging features suggest a low likelihood of a neoplasm. Additionally, malignancy predictors such as ileus and thickening of the bowel wall in the affected segment could guide tailored treatment. Surgical interventions are essential for symptomatic cases, with adenocarcinoma being the most common malignancy found in colocolic intussusceptions.Intussusception in adults is rare and is often associated with underlying tumors, particularly in colocolic intussusceptions. Key imaging predictors for malignancy include bowel obstruction, wall thickening in the affected segment, and the presence of acute abdomen, with high NPVs and specificities indicating low malignancy risk when these features are absent. Active surveillance is recommended for asymptomatic cases with low neoplasm probability, while surgical intervention is the method of choice for symptomatic patients. · Reschke P, Le Hong QA, Gruenewald LD et al. Malignancy predictors and treatment strategies for adult intestinal intussusception. Fortschr Röntgenstr 2024; DOI 10.1055/a-2434-7932.

Simultaneous Laparoscopic Hernioplasty in Urgent Pediatric Surgery

One of the variants of clinical manifestation of Meckel’s diverticulum in pediatric patients is intestinal intussusception. In this case, the surgical intervention option may be laparoscopic disinvagination and resection of the diverticulum (if the clinic is equipped accordingly) or video-assisted surgery.This article presents a clinical observation of the diagnosis and simultaneous treatment of Meckel’s diverticulitis complicated by small-colonic intussusception and necrosis of the ileum, secondary appendicitis in combination with bilateral inguinal hernia in a 5-year-old girl. The described observation demonstrates the features of the intraoperative picture and surgical treatment, and describes in detail the effective treatment tactics and the course of surgical intervention.The described variant of simultaneous treatment of surgical diseases does not affect the course of the surgical period, and also made it possible to avoid repeated intervention (hernioplasty), reduced the anesthetic load (general anesthesia) and neutralized possible surgical stress.

Colonic lipoma, a rare cause of intestinal intussusception: A narrative review and how to diagnose it.

Colonic lipomas (CLs) are benign tumors of the adipose tissue of the gastrointestinal tract that are often asymptomatic. A search of medical literature in English using PubMed and Google Scholar was conducted for articles related to CL. Occasionally, patients present with intestinal bleeding or obstructive symptoms. Although intussusception is commonly observed in children, it is rare in adults. Moreover, CL as the most common entity, is very rare, with an incidence rate of 0.035% to 4.4%. Although fatty composition can assist in diagnosis through computed tomography and magnetic resonance imaging, the latter cannot exclude local infiltration. CLs are distributed evenly between both sexes and can be located anywhere in the gastrointestinal tract; however, they are more frequently located in the colon, particularly in the right colon and cecum (39.6%), followed by the transverse colon (25%), descending colon (20.8%), and the sigmoid colon (14.6%). Symptoms included abdominal pain (79.2%), alterations in bowel habits (45.8%), rectal bleeding (22.9%), colocolic intussusception (50%), weight loss (6.2%), vomiting (14.6%), and nausea (12.5%). Surgical and endoscopic techniques are widely used to manage CLs. The challenge for physicians is differentiating this lesion from malignant colonic lesions, at the outset. The risk of misdiagnosis is possible, and the recommendation in cases of doubt is still segmental surgical resection, as it ensures correct collection of lymph nodes for appropriate staging of presumed colonic carcinoma.

Predictive Factors for Bowel Resection in Childhood Intussusception.

Intestinal intussusception is the most common cause of intestinal obstruction in infants and children under 3 years of age. Any delay in diagnosis or management can lead to intestinal ischaemia and perforation. The aim of this study is to determine the sociodemographic and clinical risk factors associated with bowel resection in infants and children with intussusception. This is a retrospective analytical study of 118 patients operated at the Hassan II Hospital and University of Fez between 1 January 2008 and 1 January 2018. A comparison of risk factors between patients with and without bowel resection was performed using multivariate logistic regression. One hundred and eighteen patients met the inclusion criteria. Of these, 44% had undergone bowel resection. Age >2 years (P = 0.006), duration of symptoms progression of more than 2 days (P = 0.002), bilious vomiting (P = 0.04) and palpation of an abdominal mass (P = 0.01) were significantly associated with bowel resection. Multivariate logistic regression showed that age <2 years (odds ratio [OR] =4.47 95% confidence interval [CI]: 1.12-17.78) and duration of symptom progression of more than 2 days (OR = 2.62 95% CI: 1.12-6.11) were independent risk factors for bowel resection. Intussusception that occurs in child old than 2 years of age, or which has progressed for more than 2 days, is associated with an increased risk of intestinal resection.

Global research landscape of Peutz-Jeghers syndrome and successful endoscopic management of intestinal intussusception in patients with recurrent laparotomies.

Peutz-Jeghers syndrome (PJS) has brought significant physical, psychological and economic burdens on the patients and their families due to its early onset, diagnostic and therapeutic challenges and increased recurrence risk. To explore the current research status and emerging hotspots of PJS. Studies on PJS published during 1994-2023 were gathered based on Web of Science Core Collection. Additionally, a case of PJS-induced intestinal intussusception, successfully treated with endoscopic methods despite three laparotomies, was highlighted. Comprehensive bibliometric and visual analysis were conducted with VOSviewer, R and CiteSpace. Altogether 1760 studies were identified, indicating a steady increase in the publication number. The United States had the highest influence, whereas the University of Helsinki emerged as the leading institution, and Aaltonen LA from the University of Helsinki was the most prolific author. Cancer Research, Oncogene and Endoscopy were the top three journals based on H-index. Keyword burst direction analysis revealed that "cancer risk", "management", "surveillance" and "familial pancreatic cancer" were the potential hotspots for investigation. Additionally, "early detection", "capsule endoscopy", "clinical management", "double-balloon endoscopy", "familial pancreatic cancer" and "molecular genetic basis" were identified as the key clusters of co-cited references. Endoscopic polypectomy remained effective on resolving intestinal intussusception in patients who underwent three previous laparotomies. In the last three decades, global publications related to PJS show a steadily increasing trend in number. Endoscopic management is currently a research hotspot.

Intestinal intussusception, colorectal cancer and intestinal endometriosis as a combined cause of intestinal obstruction: a case study

The paper describes a unique clinical case involving a patient with two tumours of mesenchymal and epithelial origin, along with ectopic endometriosis located within the cecum. This combination of pathologies resulted in colonic intussusception and subsequent colon-small intestine obstruction due to a cecal lipoma, compounded by colorectal cancer in the same area with local endometriosis foci. The surgical intervention involved laparoscopic resection of the terminal ileum, cecum, ascending, transverse, and descending colon, along with D2 lymphadenectomy and laparoscopically assisted ileosigmoid anastomosis. The patient was discharged in satisfactory condition on the 7th day post-surgery. This clinical observation garnered significant attention due to its atypical presentation of a rare complication, initially leading to a misdiagnosis and necessitating extensive intestinal resection for cancer under urgent circumstances with adequate lymph node dissection. Furthermore, the favourable treatment outcome despite the long-term presence of intussusception for at least one month underscores the noteworthy aspect of this case.

When synchronous mucinous metaplasia and neoplasia of the female genital tract and peutz-jeghers syndrome meet: a case report and literature reviews

BackgroundPeutz-Jeghers syndrome (PJS) is characterized by the presence of hamartomatous polyps in the gastrointestinal tract and mucocutaneous pigmentation on the lips, oral mucosa, nose, fingers, and toes. Synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN-FGT) refers to the occurrence of multifocal mucinous lesions in at least two sites, including the cervix, uterus, fallopian tubes, and ovaries, in the female genital tract. SMMN-FGT and PJS are rare diseases with a very low incidence, especially when occurring simultaneously.Case presentationWe report a case in which a woman with a large mass on the left ovary underwent a gynecological surgery and was diagnosed with cervical gastric-type adenocarcinoma and mucinous lesions in the endometrium, bilateral fallopian tubes, and ovary, i.e., SMMN-FGT, by postoperative paraffin pathology. The patient sought medical attention for abdominal distension and enlargement. A gynecological ultrasound revealed a multilocular cystic mass in the pelvis, while serum tumor markers were within normal limits, with mildly elevated carbohydrate antigen 199 and carbohydrate antigen 125 levels. Cervical thin-prep cytology test result was negative. The patient had a family history of PJS with black spots on her skin and mucous membranes since the age of 8 years. She underwent multiple partial small bowel resections and gastrointestinal polypectomy owing to intestinal obstruction and intussusception. She underwent left adnexectomy, hysterectomy, right salpingectomy, greater omental resection, appendectomy and right ovary biopsy, and received six courses of adjuvant chemotherapy with Lopressor plus Carboplatin. Genetic testing revealed a heterozygous serine threonine kinase 11 germline mutation and there were no signs of recurrence during the 18-month follow-up period after treatment.ConclusionsThis is a rare case in which PJS was complicated by SMMN-FGT. Owing to its extreme rarity, there are no guidelines, but reported cases appear to indicate a poor prognosis. We retrospectively reviewed all cases of collisions between PJS and SMMN-FGT and explored the clinical features, pathological characteristics, diagnosis, treatment methods, and prognosis when the two diseases coexisted. The aim is to deepen the clinicians’ understanding of this disease for early detection, diagnosis and treatment.

Clinical characteristics and literature review of ectopic gastric mucosa in the small intestine

The study aims to summarize the clinical characteristics of patients with ectopic gastric mucosa in the small intestine, comparing clinical presentation differences between domestic and foreign patients through literature review. The clinical characteristics of cases diagnosed with ectopic gastric mucosa in the small intestine at Peking Union Medical College Hospital from January 2000 to January 2024 were retrospectively analyzed. By searching databanks, such as PubMed, EMBASE, the Cochrane Library, Wanfang, VIP, CNKI, and etc (the inclusion period was from the establishment of the database to January 1, 2024). The literature review was conducted on ectopic gastric mucosa in the small intestine. A total of 10 cases were included, all male, age [M (Q1, Q3)] was 27 (13-69) years old. Gastrointestinal bleeding was the first manifestation in most cases, with severe cases leading to hemorrhagic shock. Abdominal CT indicated local intestinal wall thickening and luminal narrowing in 3 cases. Four cases lesions were located at the beginning of the jejunum and 6 lesions were located in the end segment of ileum. All cases underwent local lesion resection, with postoperative pathology confirming ectopic gastric mucosa. Symptoms disappeared postoperatively, with a follow-up period of 0.5-3.0 years. Literature review indicates that the main clinical manifestation of gastric mucosa ectopia in the small intestine in China is gastrointestinal bleeding, while foreign patients are often complicated with intestinal duplication and intussusception, with abdominal pain and vomiting as the primary and main symptoms. The occurrence rate of intestinal obstruction in female patients, both domestically and abroad, is higher than that in male patients. The occurrence rate of ileal lesions with intestinal obstruction and small intestinal duplication is higher than that of duodenal lesions in both domestic and foreign patients. Local small intestine resection is an effective treatment method with generally good prognosis. Ectopic small intestinal mucosa is relatively rare, with symptoms of gastrointestinal bleeding and intestinal obstruction being common presentations, which can serve as one of the differential diagnoses for unexplained gastrointestinal bleeding.

LYMPHOME DIFFUS A GRANDES CELLULES B REVELE PAR UNE INVAGINATION INTESTINALE CHEZ LE GRAND ENFANT : A PROPOS D’UN CAS ET REVUE DE LA LITTERATURE

Intussusception occurs when an intestinal segment and its mesentery penetrate and become embedded in the downstream intestinal segment, forming a mass called an “intussusception sausage”. It is known that it can occur on a tumor in older children. Observation: We report the case of a 10-year-old child who was admitted to the emergency room of the Regional Hospital Center of Sokodé/Togo for chronic, recurrent abdominal pain and constipation for 2 months. The diagnosis of intestinal intussusception suggested during the clinical examination was confirmed on abdominal ultrasound: ceco-colo-colicintussusception. The tumor cause of the intussusception was determined intraoperatively during laparotomy. We performed tumor resection and intestinal anastomosis. The histological examination of the tumor specimen revealed a diffuse large B-cell lymphoma. The evolution after a course of chemotherapy was satisfactory and the two-year follow-up showed no recurrence. Conclusion: Intestinal intussusceptions can be a way of revealing tumors when they occur beyond early childhood. The precision of the benign or malignant nature of these tumors is crucial and determining for the treatment and the prognosis. Keywords: Intestinal intussusception, child, tumor, treatment, prognosis

Two intussusceptions in a single infant

Acute intestinal intussusception (AII) is the telescoping of one segment of the intestine and its mesentery into the lumen of the adjacent intestine. It is the most common abdominal emergency in young children between 3 months and 3 years old but can occur at any age. We report the case of a 4-month-old infant.

Intestinal intussusception as a postoperative complication of gastric bypass

Intestinal intussusception as a postoperative complication of gastric bypass

Acute Intestinal Intussusception in Children at Somine Dolo Hospital in Mopti

Introduction: It is defined as the penetration of an intestinal segment and its meso into the lumen of the distal segment by a glove-like turning mechanism (invagination sausage) whose perpetuation results in obstruction of the intestinal lumen and the intestinal necrosis. Acute intestinal intussusception (IIA) or intussusception is the most common cause of intestinal obstruction in infants. IIA is primary or idiopathic in 90% and mainly affects infants between 2 months and 2 years with a peak frequency between 6 and 9 months. Objectives: To study acute intestinal intussusception in children aged 0 to 15 years in the general surgery department of the “SOMINE DOLO” hospital in Mopti. Method: This was a retrospective, descriptive study which took place from January 2017 to September 2020 in the general surgery department of the Sominé Dolo Hospital in Mopti. Result: During the study period, 1244 children were operated on including 32 cases of IIA, representing a frequency of 2.57% of surgical interventions. The male gender was in the majority (62.5%) with a sex ratio of 1.7. The average consultation time was 6.2 ± 4.3 days. Infants were the majority in 68.8% of cases and the main reason for consultation was abdominal pain (78.1%). The average treatment time was 2.9 hours. The ileocecocolic form was more frequent in 50% cases. Manual disinvagination was most often performed in 75% and the postoperative course was simple in 56.3%. Conclusion: AII is a common condition in our structure. It mainly affects infants and boys. Patients consult late but early treatment reduces mortality.

Ileo-ileal intussusception secondary to malignant metastatic melanoma: a case report

Intestinal intussusception in adults is a rare manifestation and almost certainly represents a pathological lead point such as a neoplasm. We present such a case of ileo-ileal intussusception with an extraluminal deposit of metastatic melanoma (MM) acting as a lead point. A 48-year-old gentleman presented with small bowel obstruction secondary to ileo-ileal intussusception. His past medical history included an advanced cutaneous melanoma awaiting work-up. An emergency laparotomy with small-bowel resection and primary anastomosis was performed. Histopathological analysis confirmed metastatic melanoma and systemic therapy was commenced. Melanoma commonly metastases to the small intestine, they often present with intussusception and small bowel obstruction or bleeding. The risk factors for metastatic spread include superficial spreading melanoma, a Clark level of III or IV, Breslow thickness above 1mm, regression, ulceration, and high mitotic rate. Diagnosis is made radiologically with CT, endoscopy, contrast studies or nuclear medicine. Emergency operative management is indicated to relieve the obstruction and definitive therapy is indicated. Malignant melanoma with distal metastases is considered a stage IV disease and such patients are subject to systemic therapy including surgical resection, chemotherapy, immunotherapy, or a combination of all three. Ileo-ileal intussusception with MM as a lead point is a very rare presentation in antemortem patients. A CT scan is the investigatory modality of choice and emergency surgery is indicated to relieve obstruction and obtain histology. Prognosis is poor but novel immunotherapy agents herald opportunities even in palliative patients.

Ileal Lipoma - A Rare Cause of Ileocolic Intussusception in Adults: Case Report and Literature Review

Intestinal intussusception in adults is rare, accounting for only 5% of intestinal intussusception and almost 1%-5% of intestinal obstruction [1, 2]. The condition is detected in less than 1 in 1300 abdominal operations in 100 patients operated for intestinal obstruction. The intestinal intussusception of the adult often leads to the discovery of an organic cause that can be a tumor or not, the ratio of children to adults is greater than 20:1. We describe a rare case of ileocolic intussusception in an adult secondary to an ileal lipoma.

Acute Intestinal Invagination in Adults Relating to Internal Hernia: A Case Report

Acute intestinal intussusception is a pathology of infants and small children. Its occurrence in adults is rare. Its etiology is diverse. In the vast majority of cases, it is secondary to a tumor, which may be benign or malignant. We report the case of a 31-year-old patient, operated on in August 2022 for appendicular peritonitis, admitted to the emergency department of the Hassan II University Hospital in Fez, Morocco, for an intestinal obstruction. The abdominal CT scan showed an acute intestinal intussusception, and treatment was open surgical resection. Based on this new case and a review of the literature, we discuss the clinical features, diagnosis and therapeutic possibilities of this rare pathology.

Inverted Meckel’s diverticulum as a cause of intestinal intussusception in a child: A case report

One of the causes of intussusception is the presence of Meckel’s diverticulum. Although Meckel’s diverticulum is the most common anomaly of the gastrointestinal tract, isolated cases of intussusception caused by the inversion of Meckel’s diverticulum into the lumen of the ileum have been described in world literature. Description of case. The patient was a 2-year-11-month boy who was transported by an ambulance team, with complaints of paroxysmal abdominal pain and single vomiting. Palpation revealed lower abdominal pain without signs of peritoneal irritation. The child underwent an ultrasound examination of the abdominal cavity, which revealed a layered structure consisting of the wall of the large and small intestines in the right lower quadrant. Thus, a diagnosis of intussusception was established. An attempt to conservatively straighten the intussusception during pneumoirrigoscopy was ineffective. Emergency laparoscopy was performed, and ileocecal intussusception was diagnosed, which was eliminated without technical difficulties. During the inspection of the ileum, a crater-shaped depression with a dense formation extending from it into the intestinal lumen was discovered on its antimesenteric edge 30 cm from the ileocecal angle. The operation was continued with a minilaparotomy in the right iliac region. Meckel’s diverticulum was manually inverted from the ileum, tied at the base, and cut off with the stump immersed in a purse-string suture. The postoperative period was event-free. On day 5 after the operation, the child was discharged home in a satisfactory condition. For any intussusception in children aged 1 year, the anatomical causes must be excluded, except for the possibility of an inverted Meckel’s diverticulum. Therefore, after successful intestinal disinvagination, a thorough revision of the ileum is necessary.

Small intestinal polyps in adults: complications, diagnosis and treatment problems

A case from practice is presented, demonstrating the development of small-intestinal intussusception in a patient, the pathogenetic cause of which was polyps of the small intestine. Despite the fact that the patient twice, before entering the surgical clinic with acute intestinal obstruction, came to the attention of medical workers (the first time with signs of gastrointestinal bleeding, the second time with abdominal pain), the patient was not properly examined, although, retrospectively, it can be assumed that the arsenal of diagnostic methods that were at the disposal of physicians made it possible to make a correct clinical diagnosis. With a very high degree of probability, it can be argued that in both cases, the cause of the patient's problems was the polyps of the small intestine. During the last hospitalization, the patient, despite the preoperative diagnosis that was not entirely accurate in terms of the wording, but absolutely correct in terms of tactics, was promptly performed an adequate surgical intervention in terms of volume. Particular attention of surgeons is drawn to the mandatory need for careful palpation and visual revision of all parts of the small intestine when performing surgical interventions for completed small intestinal intussusceptions.