Intervertebral Motion Segment Research Articles

Dynamic interactions between lumbar intervertebral motion segments during forward bending and return

Continuous dynamic multi-segmental studies of lumbar motion have added depth to our understanding of the biomechanics of back pain, but few have attempted to continuously measure the proportions of motion accepted by individual levels. This study attempted to compare the motion contributions of adjacent lumbar levels during an active weight bearing flexion and return protocol in chronic, non-specific low back pain (CNSLBP) patients and controls using quantitative fluoroscopy (QF).Eight CNSLBP patients received QF during guided standing lumbar flexion. Dynamic motion sharing of segments from L2 to S1 were calculated and analysed for interactions between levels. Eight asymptomatic controls were then matched to the 8 patients for age and sex and their motion sharing patterns compared.Share of intersegmental motion was found to be consistently highest at L2-L3 and L3-L4 and lowest at L5-S1 throughout the motion in both groups, with the exception of maximum flexion where L4-L5 received the greatest share.Change in motion sharing occurred throughout the flexion and return motion paths in both participant groups but tended to vary more at L4-L5 in patients (p < 0.05). In patients, L5-S1 provided less angular range (p < 0.05) and contributed less at maximum bend (p < 0.05), while L3-L4, on average over the bending sequence, provided a greater share of motion (p < 0.05).Intervertebral motion sharing inequality is therefore a normal feature during lumbar flexion. However, in patients, inequality was more pronounced, and variability of motion share at some levels increased. These effects may result from differences in muscular contraction or in the mechanical properties of the disc.

Surgical Treatment of the Painful Motion Segment

Literature review of current bone graft technology and bone graft substitutes used in spinal fusion applications. We reviewed current bone graft technologies and identified the range of bioactive properties that each possesses, such as osteoconductivity, osteoinductivity, and structural, load-bearing capabilities that can be used to either augment or replace autogenous bone graft in spinal fusions. Bioactive materials are used in spinal fusion applications to encourage bone formation across an intervertebral motion segment. To be an effective replacement for autogenous bone grafts, a bioactive material must possess the properties of osteoinduction and osteoconduction. Literature review. Platelet gel concentrates deliver nonspecific cytokines that influence local cells at the implantation site. Demineralized bone matrix acts as a bone graft enhancer that excludes fibrous tissue of muscle interposition in a fusion mass and is a mildly osteoinductive material. Bone morphogenetic proteins are an integral part of natural bone formation response. They function as differentiation factors that act on mesenchymal stem cells to induce bone formation. Patient-derived therapies such as platelet gel concentrates contain cytokines that play a role in bone formation; however, none of them is capable of inducing the entire bone formation cascade. Clinical use of these concentrates could possibly interfere with new bone formation. The use of bone marrow aspiration and concentration techniques has not been convincingly studied in spinal fusions in lower order animal or human clinical studies. Demineralized bone matrix contains small and variable amounts of naturally occurring bone morphogenetic proteins. These products can only function as bone graft extenders. Recombinant bone morphogenetic protein products contain much more highly concentrated and focused amounts of bone morphogenetic proteins, and some have been shown to be clinically effective bone graft replacements.

Biomechanical study of adjacent intervertebral motion after lumbar spinal fusion and flexible stabilization using polyethylene-terephthalate bands.

Thirty fresh-frozen calf cadaveric spinal specimens (L3-L6) were used to investigate the effect of flexible stabilization and fixation on the adjacent intervertebral motion segment. The intact spine that had not been subjected to injury was used for comparison as control. The destabilized spine was made up of specimens from which the bilateral facet joints and the supraspinous and interspinous ligaments were removed. The flexible stabilized spine was applied with pedicle screws and polyethylene-terephthalate bands, and the fixed spine was applied with pedicle screws and rods at the L4-L5 segment. The range of motion (ROM) was measured under flexion, extension, and bilateral bending moments, and the ROM ratio (ROM of each model versus ROM of the comparison model) was calculated at L3-L4, L4-L5, and L5-L6 segments. In the flexible stabilized spine, the restriction of motion was high under flexion and bilateral bending moments, and the mobility of the adjacent intervertebral motion segments approximated the normal lumbar vertebra. In the fixed spine, the ROM ratio increased at the cranial and caudal adjacent segments.

Sideflexion induced lumbar spine conjunct rotation and its influencing factors

Twenty motion segments from four male post mortem subjects with a mean age of 29 years were moved into the lumbar spine test positions of extension/left sideflexion, extension/right sideflexion, flexion/left sideflexion and flexion/right sideflexion Jheconjunct rotation (CR) that occurred was measured from a photographic record. The results indicated that the direction of the CR of the whole lumbar spine (ie between L1 and S1) was significantly different between the flexed and extended lumbar spine position. The direction of the CR was also significantly different between the different intervertebral motion segment levels. There was no relationship between CR and zygapophyseal joint geometry or intervertebral disc degeneration.

Three-dimensional osseo-ligamentous model of the thorax representing initiation of scoliosis by asymmetric growth

A biomechanical model of the human thorax was constructed to investigate how asymmetric growth of the thorax might initiate spinal lateral curvature and axial rotation as seen in scoliosis deformities. Geometric data specifying nodal points of the model were taken from stereo-radiographs of an adolescent subject. An initially symmetrical geometry was created by ‘mirroring’ measurements of a hemi-thorax and spine. Published data provided cross-sectional measurements of the ribs, material properties of tissues and global flexibilities of the intervertebral motion segments. The ribs, sternum, intervertebral motion segments and intercostal ligaments were represented by elastic elements. Model deformations were calculated by the direct stiffness finite element method, with growth represented by an initial strain term in the constitutive law. Non-linear behavior was accommodated by running the model recursively, with updated node locations at each step. Both stress relaxation and stress modulation of growth in the component tissues were simulated. Thoracic growth of 20% with asymmetric growth of the ribs was simulated to give rib length asymmetries of 11%, similar to that observed in a previous study of patients with idiopathic scoliosis. This resulted in the model having a small thoracic scoliosis curvature convex toward the side of the longer ribs. Variations of the model which permitted free motion at the costo-vertebral joints or produced changes in the curvature of the posterior parts of the ribs resulted in axial rotation of the vertebrae similar to that observed clinically. The model supports the idea that growth asymmetry could initiate a small scoliosis during adolescence.

Multiplanar ct in the evaluation of degenerative spondylolisthesis. A review of 150 cases

Degenerative spondylolisthesis (pseudospondylolisthesis) is a degenerative disorder of the intervertebral motion segment. It can be divided into two types: forward subluxation and backward subluxation. Forward subluxation is primarily a disease of the posterior joints and is found most commonly at L4/5. Retrolisthesis is a primary disorder of the disc space and is noted more commonly at 1–3/4. This paper reviews the CT findings in 150 patients with degenerative forward and backward subluxation. Proper evaluation of these disorders is extremely important because of the frequency of severe symptomatic spinal stenosis or foraminal encroachment.

Roentgenographic measurement of lumbar intervertebral disc height.

The influences of differences in both intervertebral motion segment orientations and in reader judgments on measurements of the apparent intervertebral disc heights in lateral roentgenographs of the lumbar spine were examined. Forty-nine roentgenographs were obtained of nine discs that were titled laterally up to +/- 10 degrees, and rotated longitudinally up to +/- 20 degrees. Three orthopaedic surgeons and three radiologists measured disc heights from five of these roentgenographs, all using the same measurement method. The differences in apparent height that resulted from the orientation changes and differences in judgments among the six readers were considerable, usually of the order of one half of the nominal disc height. The results show that, while roentgenographic measurements can be used to estimate disc height, accurate measurements cannot readily be made from routine roentgenographs, and the interpretation should always be cautious.

Mechanical Analysis of Harrington Rod Correction of Idiopathic Scoliosis

Correction by Harrington instrumentation of six idiopathic scoliotic spines was studied through computer simulation. As the limit to lateral correction is approached, large force increases are needed to increase correction, beyond those likely to be achieved by improvements in hook fixation, for example. Significant derotation should not be expected in a Harrington procedure, and is likely to be achieved within a short time only by reducing intervertebral motion segment stiffnesses. Correction of the lateral curve and correction of the rotation were not dependent on one another.