Abstract In the USA, politics often dominates the conversation surrounding science and related technologies. We also live in times of high political polarization, leading to political debate over scientific discoveries and subsequent policy implications. Given these dynamics, there is much to be learned about the politicization of science, individuals’ policy views, and the public’s relationship with the communication and interpretation of scientific findings. Agencies are often responsible for facilitating scientific research and framing its policy relevance for decision makers and the public. This paper uses data from a large national public opinion survey to investigate citizen attitudes about government science agencies. We theorize that disparities between objective and self-assessed scientific knowledge coupled with ideological cues help frame citizen evaluations of agencies. We find that individuals’ political ideologies and disparities between knowledge types shape citizen assessments of energy-related scientific agencies. These findings have important implications for our understanding of public acceptance of the work of government science agencies.