Suicide, rooted in antiquity, is now identified as a global dilemma, particularly impacting Indigenous peoples. The backdrop for this non-systematic focused review is the worldwide challenges faced by vulnerable Indigenous peoples with untenable poverty, degraded life-quality conditions, and suicidality, while the focus, as a specific case, is on the complexity of suicidality in Canadian Indigenous high-risk age groups. The aim here is to present overt and covert intersecting factors underlying suicide in Indigenous youths and young adults in the vast Canadian context. Although living in a privileged geopolitical region, their physically remote and economically compromised communities meshed with a haunting history combined with authorities' ingrained attitudes of exclusion and neglect, spawned meager health and education resources, services, and consequent dire results. The article's guiding theoretical frameworks are Transcultural Psychiatry with its emphasis on context that explains health, illness, and recovery in groups and individuals, and the Interpersonal Psychological Theory of Suicide to identify individuals' suicidality triggers. The article highlights indigenous social determinants of health, identifies elements underlying the tragic suicidality trend in these groups, and addresses literacy and education as poverty driven issues and suicidality-contributing factors promoting attitudes of hopelessness. The discussion includes joint suicide combatting efforts by Indigenous communities and Canadian authorities, these authors' psychosocial-cognitive literacy acquisition plan to address all age-groups simultaneously, and a take-home message introducing employers' desirable worker competencies for effective future employment, thereby uplifting life-quality and prospects to help thwart the spectre of suicide. The Conclusion introduces current trends in suicidality science, confirming the authors' intervention plan is a good fit in the psychosocial intervention trend. Future directions include advice to examine the effectiveness of the plan in the Indigenous context, and tweak it accordingly. For ease of reader comprehension, the article flow is included at the start of the Introduction section.
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