Internet Resources Research Articles

Use of Russian and Kyrgyz Languages in Private Medical Centers in the Capital of Kyrgyzstan

This article examines the frequency of use of Russian, Kyrgyz and other languages in private medical centers in the capital of Kyrgyzstan, identifies the features of printed advertising texts and Internet resources that facilitate the functioning of these organizations. The article presents factual data collected during a sociolinguistic study, which are the basis for the formation of grammar language planning in one of the post-Soviet republics. Methods of social linguistics were used to collect the material. The work is of interest to linguists, sociologists, cultural scientists and historians as a source for analyzing the modern socio-linguistic situation in the former republics of the Soviet Union and the modern area of ​​the Russian-speaking space located outside the Russian Federation. In addition, the work allows doctors from different countries to form an idea of communication between colleagues and patients in private medical centers in Bishkek, which directly affects the ability to find work in this region. The scientific article provides an analysis of texts posted on websites and in the Internet space, as well as in advertising brochures, manuals, bulletins, where the dominant role of the Russian language is noted. It should be noted that the article contains an analysis of the graphics used by private medical centers when registering with the Ministry of Justice, in the media and the Internet. In this case, cases of merging Latin and Cyrillic graphics are noted, which indicates a desire to use international medical vocabulary in characterizing the specifics of many centers.

Can't Buy Me Love? The Use of Gifts in the Residency Application Process.

To set themselves apart, some programs use gifts or promotional items to highlight the residency program or unique local culture. The distinction between advertisement and persuasion may be blurry in this case. We sought to quantify the prevalence of gifts to applicants and how frequently the US federal threshold for "nominal gifts" was exceeded. We reviewed a publicly accessible, Internet resource called the "ERAS Megathread." This is a Google spreadsheet found on Reddit where applicants participating in The Match can anonymously contribute information about their experience. The incidence of "gifts" was quantified for surgical residency programs, along with the nominal value if indicated. The spreadsheets were reviewed for 2021, 2022, and 2023. Over the past 3 application cycles, 15.1% [11.1%-18.2%] of general surgery residency programs provided a gift to applicants. Of these programs, the majority (70.2%) are university-based programs. In 2023, 57.9% of these gifts exceeded US$20. Given the anonymous nature of the data set, and the lack of transparency in the match process, it was not possible to correlate gift giving with its effect on recruitment. Students are courted by residency programs, and a significant minority of programs provide a gift to applicants. The impact of a substantial gift on a financially vulnerable student is difficult to quantify. It behooves us as a specialty to determine what should be a universal standard and to consider outlining explicit guidelines for The Match.

Digital Divide: Examining Socioeconomic Inequalities in Internet Access and Usage

The term "digital divide" refers to the disparity that exists between those who have access to digital technologies, most notably the internet, and those who do not have such access. This disparity is caused by several socioeconomic, regional, and demographic reasons. The digital gap not only exacerbates existing disparities but also creates challenges for marginalized communities. This is because the Internet is becoming an increasingly vital instrument for education, communication, employment, and social involvement. The purpose of this review article is to analyze the underlying factors that contribute to these disparities, such as income, education, geographic location, and age, and to investigate the influence that uneven access to the internet has on different elements of contemporary life. In addition to this, it examines the policies and activities of the government, as well as the technical advancements that are being made to narrow this gap. Although attempts have been made to bridge the difference, the results imply that there is still a great deal of work to be done, especially in tackling structural inequities that continue to interfere with development. In conclusion, the article makes recommendations for comprehensive methods that aim to overcome socioeconomic obstacles and encourage fair access to Internet resources.

Artificial intelligence as a modality to enhance the readability of neurosurgical literature for patients.

In this study the authors assessed the ability of Chat Generative Pretrained Transformer (ChatGPT) 3.5 and ChatGPT4 to generate readable and accurate summaries of published neurosurgical literature. Abstracts published in journal issues released between June 2023 and August 2023 (n = 150) were randomly selected from the top 5 ranked neurosurgical journals according to Google Scholar. ChatGPT models were instructed to generate a readable layperson summary of the original abstract from a statistically validated prompt. Readability results and grade-level indicators (RR-GLIs) scores were calculated for GPT3.5- and GPT4-generated summaries and original abstracts. Two physicians independently rated the accuracy of ChatGPT-generated layperson summaries to assess scientific validity. One-way ANOVA followed by pairwise t-test with Bonferroni correction were performed to compare readability scores. Cohen's kappa was used to assess interrater agreement between the two rater physicians. Analysis of 150 original abstracts showed a statistically significant difference for all RR-GLIs between the ChatGPT-generated summaries and original abstracts. The readability scores are formatted as follows (original abstract mean, GPT3.5 summary mean, GPT4 summary mean, p value): Flesch-Kincaid reading grade (12.55, 7.80, 7.70, p < 0.0001); Gunning fog score (15.46, 10.00, 9.00, p < 0.0001); Simple Measure of Gobbledygook (SMOG) index (11.30, 7.13, 6.60, p < 0.0001); Coleman-Liau index (14.67, 11.32, 10.26, p < 0.0001); automated readability index (10.87, 8.50, 7.75, p < 0.0001); and Flesch-Kincaid reading ease (33.29, 68.45, 69.55, p < 0.0001). GPT4-generated summaries demonstrated higher RR-GLIs than GPT3.5-generated summaries in the following categories: Gunning fog score (0.0003); SMOG index (0.027); Coleman-Liau index (< 0.0001); sentences (< 0.0001); complex words (< 0.0001); and % complex words (0.0035). A total of 68.4% and 84.2% of GPT3.5- and GPT4-generated summaries, respectively, maintained moderate scientific accuracy according to the two physician-reviewers. The findings demonstrate promising potential for application of the ChatGPT in patient education. GPT4 is an accessible tool that can be an immediate solution to enhancing the readability of current neurosurgical literature. Layperson summaries generated by GPT4 would be a valuable addition to a neurosurgical journal and would be likely to improve comprehension for patients using internet resources like PubMed.

МОЖЛИВОСТІ ВИКОРИСТАННЯ МОБІЛЬНИХ ТЕХНОЛОГІЙ ПІД ЧАС ПРОВЕДЕННЯ НАВЧАЛЬНОГО ФІЗИЧНОГО ЕКСПЕРИМЕНТУ

The article discusses modern approaches to the integration of mobile technologies into the educational process, in particular during physical experiments. The potential of mobile devices, such as smartphones and tablets, to perform experimental tasks in physics has been analyzed, which significantly expands the capabilities of educational laboratories and increases the efficiency of the educational process. The purpose of the article is to clarify the expediency of using mobile technologies during the organization and conduct of an educational physical experiment. The research was based on a comprehensive approach, which included the analysis of scientific and methodical sources, periodicals, Internet resources regarding the possibilities of using mobile technologies in the educational process, in particular in the study of physics. Modern mobile applications, tools and platforms that can be used in educational physical experiments were also analyzed. The main attention is paid to mobile applications that make it possible to measure physical quantities, model and visualize physical processes in real time. The use of such technologies greatly simplifies conducting experiments both in the classroom and in distance learning conditions. It is emphasized that mobile technologies make it possible to reduce the need for expensive laboratory equipment. This makes education more accessible to a wide range of students. The advantages of using mobile technologies during physical experiments are highlighted, including convenience, accessibility, the possibility of instant data analysis and their visualization. In addition, the issue of individualization of training is taken into account, when each student can work independently at his own pace, using various applications and technologies. Mobile devices allow you to conduct physical experiments even at home, which significantly expands the opportunities for independent work of students.

ECOLINGUISTIC REVIEW OF THE INTERNET LINGUOCYNICISMS

The purpose. The purpose of the article is to study of the impact of Internet communication on the language behaviour of users, the identification of specific linguistic changes and their shades in this environment, as well as the analyse the ecological consequences of these phenomena. Methodology. The research is based on the use of the ecolinguistic approach, which combines the methods of linguistics, ecology and cultural studies. Methods of analysis include descriptive analysis of language means, content analysis of Internet resources, as well as observation of the language practice of users. The use of a multi-method approach allows readers to get a comprehensive picture of the phenomenon of linguistics on the Internet. Methods such as analysis and synthesis of literature on the research problem, web scraping, analysis of social networks, discourse and content analysis were also used in the research. Scientific novelty. The article reveals a new aspect of language learning in the context of the modern digital environment. The study reveals unique linguistic features that occur online, such as language abbreviations, the use of emojis, and other forms of non-standard communication. The impact of these phenomena on language culture and ways of expressing thoughts and feelings is analyzed. The article analyzes for the first time the interaction between language practice in the online environment and the natural environment, highlighting the impact of the Internet language on the language ecosystem and cultural landscape in general. Changes in the presentation of language units to the public can be clearly traced through the ecolinguistic prism. In addition, language clogging is traced and ways to overcome linguocynicisms are provided. Conclusions. The results of the study indicate that the Internet significantly affects the evolution of language, creating new linguistic realities and changing the ways of communication. Awareness of these changes is important for the further development of linguistics and society as a whole. Investigating the ecolinguistic aspects of Internet linguocynicisms can be an important contribution to understanding the interaction between language, culture, and technology.

The necessity and demand of machine learning in treatment and diagnostics in dentistry

Aim: to justify the necessity of machine learning technology in treatment and diagnostics in dentistry.Material and methods: the research was taken using the method of anonymous questionnaire to estimate the demand and necessity of machine learning technology in diagnostics and treatment in dentistry on the basis of the E.V Borovsky Institute of Dentistry I.M Sechenov First Moscow State Medical University (Sechenov University). 100 participants from different dental specialities aged 20 to 54 took part in the questionnaire. Wilson score interval and Student’s T Critical Values were used for the statistical analysis of the Results.Results: during the study, it was found that the majority of dentists who participated in the questionnaire (54%) have challenges in diagnosing oral mucosal diseases. Herewith dentists with work experience more than 5 years diagnose this kind of disease more frequently than specialists with less work experience (p&lt;0.05). Surgical dentists (46,6%) and prosthetic specialists (50%) diagnose this pathology most often. Clinicians attribute diagnostic challenges to the lack of experience (85%) and low occurrence of patients with this group of diseases. During treatment and diagnostics 84% of residents mentioned that they compare their patients’ clinical cases with clinical cases from the Internet and other resources, 78% of residents believe that machine learning will help to increase the efficiency of diagnosing oral mucosal diseases in clinical work. During the held research, it was found that 85% of participating dentists would definitely use digital programs with machine learning in their clinical work for treatment and diagnostics.Conclusions: the presence of problems in treatment and diagnostics of oral mucosal diseases was confirmed, and to solve it, the demand and the need to develop and implement digital systems based on artificial intelligence using machine learning technology were substantiated.

Features of the use of digital technologies when teaching the Russian language to foreign citizens in Russian universities

Introduction. Currently, the education system around the world is undergoing a number of changes due to the active development of distance and digital learning technologies: learning is becoming more individualized, flexible, dynamic, and most importantly, technologically advanced. In these conditions, it seems necessary to rethink the role and specifics of using digital technologies when teaching Russian to foreign students. Materials and methods. The study involved 60 teachers of Russian as a foreign language aged from 25 to 67 years old, working at various universities in Russia: Peter the Great St. Petersburg Polytechnic University, St. Petersburg Mining University, Herzen State Pedagogical University, etc. The following methods were used: questionnaire method, comparative analysis, statistical method, systematization method, as well as a method of graphical presentation of data. Research results. The survey revealed that the majority of Russian as a foreign language teachers (78%) consider the digitalization of higher education to be a positive phenomenon, and 60% of respondents currently conduct their classes in a mixed mode. The most common digital tools used are basic computer programs (96%), instant messengers/email (85%), Internet resources (84%), platforms for conducting distance learning (81%) etc. The vast majority of respondents (95%) made changes to the process of teaching Russian language, taking into account the experience of the distance mode: they began to use the latest teaching methods, digital resources etc. 32% of survey participants believe that the use of electronic technologies is most relevant at the stage of skill building; speaking about teaching various types of speech activity and aspects of language, 80% of teachers noted that the use of electronic technologies is most appropriate when teaching listening and vocabulary. The majority of respondents believe that the use of digital technologies makes it possible to optimize control over the mastering of educational material. Conclusion. The obtained research results made it possible to identify and describe the most important aspects of the digitalization of higher education in the field of methods of teaching Russian as a foreign language, as well as to determine the prospects for further methodological study of the use of digital technologies in Russian as a foreign language classes.

AI chatbots and political learning

ABSTRACT We preregistered and experimentally tested six hypotheses assessing AI chatbot effects on political learning. We randomly assigned subjects to the AI chatbot ChatGPT, Google Search, or a control group with no stimulus or outside assistance in two nationally representative survey experiments on U.S. crime rates and vaccine safety. Subjects using AI chatbots learn more than those with no Internet resources and are confident in what they learn. However, none of these attributes from AI usage were substantively different from those using Google searches in both samples and topics. Directly engaging with ChatGPT increases subjects’ comprehension of their researched content compared to Google. These findings suggest that AI chatbots help promote political learning but are not necessarily more impactful than traditional Internet searches. The impact of AI evolution on shaping political discourse and public knowledge warrants further exploration.

The influence of trekkers’ personal and subjective norms on their pro-environmental behaviors

The call for pro-environmental behaviors (PEBs) is increasing amid the growing negative impact of human activity on the environment. Most studies in this domain have focused on the environmental impact of specific human behaviors, overlooking how these behaviors evolve over time. The purpose of this study is to elucidate how trekkers maintain and practice environmentally friendly behaviors in daily life. To achieve this goal, this study examined the influence of subjective norms and personal norms on daily PEBs and adopted environmental awareness as a mediating variable. This study recruited trekkers in Taiwan (n = 528) as the research subjects and employed structural equation modeling to test the proposed hypotheses. The results showed that subjective norms, personal norms, and their interaction effects all indirectly influenced PEBs through environmental awareness. In particular, the influence of subjective norms was much greater than that of personal norms, indicating that people's behaviors are more significantly impacted by others' expectations than by their own personal beliefs. These findings not only highlighted the importance of subjective and personal norms in shaping PEBs but also revealed that the PEBs cultivated during trekking activities may extend to behaviors in daily life. Management implicationsThis study offers practical implications for management teams and practitioners at trekking destinations: they should promote daily PEBs and effective communication with trekkers. Since 2020, the number of trekkers in Taiwan has surged by 57%, resulting in significant environmental degradation. This increase can largely be attributed to insufficient staffing, as the overwhelming number of trekkers places additional burdens and stress on existing personnel. Therefore, it is essential to implement measures to regulate the number of trekkers in sensitive areas. Furthermore, the government should enhance recruitment efforts for mountain rangers to ensure adequate oversight and support.Trekking activities often take place in remote and sparsely populated mountainous areas, where the natural environment is relatively undisturbed. As a result, environmental management faces greater challenges in these regions. In this context, local governments should consider adopting nature-oriented recreation and tourism activation strategies through direct and indirect experiences. These could include formal and informal educational programs and services, mass media, internet resources, and interpretive programs. Such initiatives aim to enhance human understanding, knowledge, and appreciation of nature, thereby shaping personal norms and subjective norms while fostering environmental awareness.In terms of durable outcomes, it is recommended that destination management agencies and environmental protection organizations invite trekkers to participate in destination environmental management and provide a platform for expression, organize public welfare activities (such as mountain garbage cleanup, and tree planting), and provide spiritual incentives and economic rewards, durable outcomes for travelers and continued PEB (Liu et al., 2024).

İnternet provayderlərin məsuliyyətinə dair təcrübənin Azərbaycan, Türkiyə və Avropa hüquqi tənzimlənməsi əsasında müqayisəli təhlili

In the article, a comparative analysis of the practice of the liability of Internet providers is carried out based on the legal regulation of Azerbaijan, Turkey and Europe. It is noted that the issue of responsibility of providers for the content shared in the virtual space is based on the regulation of the Internet and information legal responsibility as a unity of two main information legal research topics. In the end, it is concluded that Internet providers are not classified in the legislation of the Republic of Azerbaijan. Thus, the terms host provider, Internet information resource owner, and telecommunications operator and provider are used. Only the legal understanding given to the host provider complies with international norms and best foreign practices. The lack of basic legal concepts also makes it difficult to solve the issues of responsibility in case of violation of rights and freedoms. Keywords: Internet provider, virtual space, Internet regulation, information-legal responsibility, Internet information resource, rights and freedoms, legal regulation.

Container migration for edge computing in industrial Internet with joint latency reduction and reliability enhancement

Edge computing has emerged as a prominent trend in the field of information technology, offering flexible and robust resources for the industrial Internet. How to migrate container accurately is crucial for edge computing in the industrial Internet, as it plays a vital role in enhancing service response speed and safeguarding uninterrupted continuity of production operations. In this paper, we explore the problem of container migration in edge computing within the industrial Internet, aiming to reduce latency and enhance reliability. We establish a two-objective optimization model to comprehensively capture the container migration problem and formulate it as a constrained optimization model. The formulated model provides a systematic framework that effectively balances the trade-off between reducing latency and enhancing reliability. To tackle the migration strategy derived from the optimization model, we propose a migration algorithm based on the improved binary whale optimization algorithm. Our migration algorithm incorporates the adaptive probability and adaptive position weight within the hunting and searching operations, effectively enhancing the search efficiency during the solving process. The experimental results demonstrate the effectiveness of the established model in reducing the objective value, while the proposed migration algorithm surpasses existing algorithms by achieving an average reduction of at least 15.59% in the objective value.

33 Use of CHU Ste. Justine online resources prior to visiting the Emergency Department for less-urgent, acute febrile illness

Abstract Background Over the past 20 years, visits to paediatric emergency departments (EDs) across Canada have steadily increased, with a higher proportion of presentations for lower acuity symptoms. Many paediatric institutions’ websites now provide information and recommendations for caregivers on common illnesses and reasons for seeing healthcare providers or going to the ED. Increasing the use of internet resources may improve health literacy and hopefully decrease ED use for lower acuity presentations like uncomplicated viral illness. Objectives The objective of this study was to assess whether caregivers presenting with children with lower acuity at triage were aware of and using the online resources provided by our paediatric institution to help with at-home management of febrile illnesses and to guide their decision to present to the ED. Design/Methods This was a cross-sectional study in a tertiary care university-affiliated paediatric ED in an urban setting. Participants were a convenience sample of caregivers of children 6 months to 17 years old with a fever 72 hours or less and triaged low acuity (Canadian Triage and Acuity Scale levels 3 to 5). Caregivers of children with underlying significant systemic illness were excluded. Consenting participants completed two questionnaires. The first questionnaire included demographic data, information on baseline internet utilisation, use of general online health information and our institutions’ website specifically, and whether use of those resources influenced their decision to present to the ED. After browsing dedicated web materials developed by our institution (“Before going to the emergency room” and “Fever”), questionnaire 2 asked for feedback on the website. Results From April to July 2023, 100 caregivers participated in the study (response rates questionnaires 1 and 2: 80% and 70%, respectively) (Table 1). Half (49%) of caregivers researched their child’s symptoms prior to coming to the ED (Table 2). Approximately one third (39%) of respondents were aware that our institution provided online information for caregivers about common symptoms and when to present to the ED. Half (51%) of caregivers who completed questionnaire 2 said they would not have come to the ED if they had read these resources prior (Table 3). Many (66%) respondents reported they would be “likely/very likely” to look up their child’s symptoms on the institutional website before going to the ED in the future. Conclusion Half of caregivers presenting to the ED for their child’s lower-acuity febrile illness conducted research on their child’s symptoms prior to visiting the ED and most were influenced in their decision to come to ED by what they found. Most caregivers were not aware that our institution had online resources available. Promotion of the institutional resources available to parents may empower parents to manage common symptoms at home and prevent ED visits for lower-acuity illness.

Perspectives of Czech High School Students on Cheating in Remote Education

This study explores the perspectives of Czech high school students on using digital technologies for cheating during remote education, a phenomenon encouraged by the abrupt transition to online learning due to the COVID-19 pandemic. Through a mixed-methods research design, this study collected data via an online questionnaire with 24 questions completed by 316 students from secondary schools and conducted individual interviews with seven teachers. In their study, the authors focus on three questions: How much do high school students know which digital technology they can use for cheating in remote online education? What are their experiences with cheating in remote online education? What are the preventive solutions recommended by students and teachers to eliminate online cheating? The research findings indicate that students perceive online cheating as justifiable, primarily due to their disengagement with the course material and lack of interest in learning under the pandemic's extraordinary circumstances. Students frequently used technical means for cheating, with mobile phones and screen-sharing during online tests being the most popular methods. Additionally, the use of internet resources to find answers was the most commonly reported form of online cheating. To address this issue, students outlined various anti-cheating strategies, categorised into three perspectives: pessimistic, practical, and critical-realistic. The pessimistic perspective indicates scepticism about the feasibility of effectively combating cheating, whereas the practical perspective offers tangible, immediate solutions. The critical-realistic view provides a thoughtful and pragmatic approach to the problem, suggesting a balance between understanding the complexities of cheating and implementing realistic measures. The study highlights educators' critical role and emphasises the importance of aligning assessment methods with students' learning needs and expectations to reduce cheating tendencies naturally. The rise of AI technologies has introduced new dimensions to the problem of online cheating, as AI tools can facilitate academic dishonesty. However, AI can help detect and prevent cheating. The authors suggest using formative assessments and creating an engaging, supportive online learning environment to deter dishonesty and promote academic integrity.

How Students Behave while Solving Critical Thinking Tasks in an Unconstrained Online Environment: Insights from Process Mining

To learn successfully with the use of various internet resources, students must acquire critical thinking skills that will enable them to critically search, evaluate, select and verify information online. Defined as Critical Online Reasoning, this complex latent construct manifests itself in an unconstrained online environment and is measured on two levels: students’ work product (an essay) and the process of task completion (online behaviour patterns). This research employs process mining techniques to investigate the possibility of distinguishing between students’ successful and unsuccessful attempts to take the test. The findings of the work were gained on generalised behaviour patterns from the process mining algorithm deployed on two groups of students (63 low performing and 45 high performing students). Divided by the work product score, the two groups exposed some differences in their online behaviour, with the high performers showing more strategic behaviour and effective search and use of information online. However, the research has also shown the downside of process mining as a tool for generalisation of process patterns.

Empirical Study on the Influence of Internet Use on the Employability of Local College Students

Based on the data of China Family Panel Studies (CFPS) in 2020, this paper analyzes the impact of Internet use on the employability of local college students through OLS and logit regression models. The study found that the Internet has become an important tool for local college students to improve their employability. Students who actively participate in online learning, use career recruitment platforms and social media to expand career networks in local colleges and universities show stronger competitiveness in terms of professional skills, comprehensive quality and job search skills. The importance of Internet use to work, learning and information channels has a significant impact on the employability of local college students, and has a significant moderating effect. Through heterogeneity analysis, it is found that the impact of Internet use on the employability of local college students in eastern China is significantly higher than that in central and western China : the employability of college students with urban household registration is higher than that of local college students with rural household registration, and the employability of female local college students is lower than that of male local college students. Therefore, this study suggests that local colleges and universities should further guide students to make rational use of Internet resources and strengthen network literacy education, so as to better adapt to the employment market demand and promote high-quality employment of graduates.

Meta Ads digital advertising in social networks

A progressive tool for achieving the marketing goals of retail enterprises in digital advertising in social networks, taking into account the current situation in Ukraine, is Meta Ads. Advanced targeting parameters based on demographics, interests and own audience make Meta Ads a powerful tool for digital advertising professionals, allowing them to reach a wide audience with targeted messages. The study was conducted using the following methods: data analysis, synthesis and logical generalization of results; systemic, structural and statistical analysis with the use of graphical methods. The main sources of information are scientific papers, the results of marketing research, expert blogs in the field of digital advertising, and official statistical information from Internet resources. In the article there were considered the functions of generative artificial intelligence in Meta Ads, such as image enhancement, background generation, and ad text variations, which can reduce the time required to create advertising materials. Advantage+ tools that automate the process of creating advertising campaigns and targeting have been analysed, in particular Advantage+ Shopping Campaigns and Advantage+ Creative. The development trends of Meta Ads in the Ukrainian market, which will affect the results and efficiency of work with digital advertising, are substantiated. It was determined that the use of existing artificial intelligence technologies will allow enterprises to better find the target audience and work with advertisements

Activation of Students' Cognitive Activity through Physical and Health-Improving Activities

The methodology for developing cognitive activity through physical and health-improving activities is thoroughly examined for primary school students. Regarding the methodology for developing cognitive activity through physical and health-improving activities for middle school students, there are practically few developments, and recommendations are often given in a general form. Thus, the issue of the impact of physical and health- improving activities on the cognitive activity of middle school students is still largely unexplored and has not yet received scientific substantiation. The article determines the influence of the level of physical working capacity on the cognitive activity of 6th-grade students. A method for activating cognitive activity through small forms of physical culture is presented. The study involved the analysis of literary sources and internet resources; analysis of students' academic performance; research on physical working capacity; speed of thinking; determination of the average academic score; mathematical statistics methods using the SPSS program: the Kolmogorov-Smirnov one-sample test; Pearson correlation.

THE MAIN TRENDS AND DIRECTIONS OF THE SUSTAINABLE DEVELOPMENT AND REGENERATION OF THE HISTORICAL ENVIRONMENT

Objective: The purpose of this study is an attempt to reveal and analyze the modern trends and directions of the sustainable development and regeneration of the historical environment from the point of view of the harmonious combination of new and historical architecture and to define some methodological principles of its design at the different hierarchical levels. Theoretical Framework: The study is grounded in a thorough literature review that examines existing research and is based on international scientific publications, reports, scientific papers. Diverse practical materials in the area under study were used as well as own experience in designing urban complexes and buildings in the historical environment. Methods: This study is based on a set of scientific research methods, using an extensive review of literature, Internet resources, and the views of stakeholders. Preference was given to methods such as comparative analysis, synthesis, generalization, complex and systemic approaches. Results: Research identifies key areas of the development and regeneration of the complexes and buildings in the historical environment, which can be divided into several directions. The features, conditions, and directions of such implementations on various examples are examined in this study. Some methodological principles of designing in historical areas at different hierarchical levels are considered. Research Implications: Implications of the study: The results and recommendations of this study will be useful for contemporary design practice, may increase awareness of project management in the field of architecture and urban planning, and help to manage practice in this field more effectively.

Modern alternative research methods in genetic toxicology (literature review)

The review represents the current principles of assessment of chemicals genotoxicity. The main attention is paid to alternative research methods. The international experience of the application of alternative approaches and prospects of their use for regulatory purposes are discussed. The data for this review were collected from the Russian and foreign literature, as well as Internet resources, concerning the development of the new alternative methods for testing chemicals for genotoxicity. The OECD database, Scopus, Medline, Google Scholar, RISC, CyberLeninka were used for the information retrieval. Although the evaluation of genotoxicity of chemical substances is the well-established and based on the battery of validated methods, the studies for improving the existing tests and developing new technologies, including the alternative approaches, continue unabated up to now. In general, three trends of development of genetic toxicology can be outlined, including creating of new methods based on the whole-genome sequencing and the application of genome editing technologies; implementation of quantitative system of effects assessment in addition to the existing qualitative approach (mutagenic/non-mutagenic) and testing of various combinations of genotoxicity evaluation methods to identify a battery of tests with a greater predictive activity regarding carcinogenic effects. To use the developed alternative models for regulatory purposes, it is necessary to provide convincing evidence that the data obtained are good predictors of the organism’s actual response to the effects of toxicants/genotoxicants, validation of methods, standardization, and harmonization of research protocols, and changes to the existing regulatory framework are required.