International Research Program Research Articles

COVID-19 vaccination intention among people who use drugs in France in 2021: results from the international community-based research program EPIC

BackgroundCOVID-19 vaccination is crucial to reduce the incidence of severe forms of the disease in the population. However, people who use drugs (PWUD) face structural and individual barriers to vaccination, and little is known about vaccination intention and factors associated with that intention among PWUD. This study aimed to estimate vaccination intention in PWUD and associated factors in the early stage of vaccination campaigns.MethodsWe conducted cross-sectional study in France among PWUD, as part of the international EPIC program, a community-based research study coordinated by Coalition PLUS. It included 166 unvaccinated PWUD attending harm reduction centers. A questionnaire collected data on sociodemographic characteristics, COVID-19 related difficulties, and mental health, among other things. Multivariate logistic regression was used to identify factors associated with low vaccination intention.ResultsOnly 19% of participants reported strong intention to get vaccinated against COVID-19. Factors independently associated with low vaccination intention were younger age (aOR = 0.90, 95%CI = 0.85–0.95), lower education level (aOR = 2.67, 95% CI = 0.95–7.55), and unstable housing (aOR = 6.44, 95% CI = 1.59–40.34). The most-cited reasons for low intention were mistrust in COVID-19 vaccines (66.1%), fear of side effects (48.7%), and non-belief in vaccinations in general (25.2%).ConclusionsThis study highlights the need for targeted COVID-19 information and interventions to increase vaccine uptake in PWUD, especially those living in precarity. Community-based interventions and targeted government assistance could play a crucial role in addressing vaccine hesitancy in this population, not only for COVID-19 but for future epidemics.

Facies variability and depositional cyclicity in central Northern Switzerland: insights from new Opalinus Clay drill cores

The Opalinus Clay, a silty to sandy claystone formation, Early to Middle Jurassic (Toarcian and Aalenian) in age, has been selected as the host rock for deep subsurface disposal of radioactive waste in Switzerland. Over the past thirty years, numerous geotechnical, mineralogical, and sedimentological studies have been conducted on the Opalinus Clay within the framework of the Nagra (National Cooperative for the Disposal of Radioactive Waste) deep drilling campaigns and the Mont Terri Project, an international research program dedicated to the study of claystone. The present study aims to unravel the variability of the lateral and vertical facies of the Opalinus Clay in central Northern Switzerland and to place this variability in a regional and basinal context. Analyses of new cores drilled in central Northern Switzerland, including petrographic, mineralogical (X-ray diffraction, multi-mineral interpretation), geochemical (X-ray fluorescence), statistical (non-metric multidimensional scaling analysis), and bedding dip and azimuth data, shed new light on the depositional facies and the spatial and temporal variability of the Opalinus Clay. Petrographic descriptions encompass nine new drill cores using a revised subfacies/facies classification scheme based on texture (colour, grain size, bedding) and composition (mineralogy). Particularly, one new subfacies (SF6) is described and interpreted as mass-wasting deposits. The drill cores are correlated laterally using specific marker horizons. This correlation is achieved by combining thorough facies investigations with lithostratigraphy, biostratigraphy, and chemostratigraphy. Six to seven small coarsening-upward cycles and two long-term coarsening-upward sequences can be interpreted as regressive trends. The observed trends are influenced by the interplay between sediment supply, eustatic sea level change, synsedimentary subsidence, but also the palaeogeographic configuration in an epicontinental sea, provenance and delivery of sediments, current dynamics and climate change. Finally, combined results show that the current dynamics in the Opalinus Clay has been underestimated until now and new depositional models, including the occurrence of drift deposits, are discussed.

How an international research programme can contribute to improvements in the research environment: the perspective of doctoral students in sub-Saharan Africa

Background The Africa Capacity Building Initiative (ACBI) programme aimed to ‘strengthen the research and training capacity of higher education institutions and support the development of individual scientists in sub-Saharan Africa through UK-Africa research collaborations’ including by funding PhD studentships. We conducted research to understand students’ experiences and to see how consortia-based programmes such as ACBI and their own institutions can enhance PhD students’ research environment and progress. Methods In-depth interviews with 35 ACBI-funded PhD students explored their perspectives about how their research and personal development benefitted from belonging to a research consortium. Questionnaires were used to corroborate interview findings. Results Students recognised that membership of a research consortium provided many benefits compared to less well-resourced peers. By drawing on the programme and consortiums’ resources, they were often able to overcome some limitations in their own institution’s systems and facilities. Through their consortia they could access a wide range of international expertise and support from mentors and colleagues for their technical and psychosocial needs. Multiple consortia opportunities for engaging with the international scientific community and for networking, gave them confidence and motivation and enhanced their career prospects. Conclusion Our study and its recommendations highlight how the breadth and diversity of resources available to PhD students through research consortia can be harnessed to facilitate students’ progress and to create a supportive and conducive research environment. It also underlines how, through a multi-level approach, consortia can contribute to longer-term improvements in institutional research environments for PhD students.

VSEMERA: pilot project assessing health profession students’ experiences in an international virtual research program

BackgroundThe “Virtual Semester for Medical Research Aachen” (vSEMERA) is an international, interdisciplinary, virtual education program developed for health profession students. The first edition (2021) was hosted by the Medical Faculty of RWTH Aachen University (Germany) in cooperation with Centro Universitário Christus (Brazil) and Universidad Peruana Cayetano Heredia (Peru). The primary aim of the 12-weeks program was to provide students with skills in health science research and prepare them for scientific career paths.MethodsvSEMERA was built on a virtual learning platform, the “vSEMERA-Campus”, designed to foster students’ learning process and social interactions. Maximum flexibility was offered through synchronous and asynchronous teaching, enabling participants to join via any device from any part of the Globe alongside their regular studies. For the program’s first edition (September - November 2021), health profession students from Germany, Brazil, Peru, Spain, and Italy filled all 30 available spots. Satisfaction, quality of the program and courses offered, as well as perceived learning outcomes, were examined using questionnaires throughout and at the end of the program.ResultsThe program received a rating of 4.38 out of 5 stars. While it met most expectations (4.29 out of 5), participants were unable to attend as many courses as intended (2.81 out of 5), mainly due to scheduling conflicts with the home university schedule (46%), internships (23%), and general timing issues (31%). Participants acknowledged considerable improvements in their scientific skills, English language skills, confidence in scientific project management, research career progression, and enthusiasm for a scientific career.ConclusionsvSEMERA represents a promising example of an online international learning and exchange program using pedagogical and technological elements of virtual collaboration and teaching. In addition to advancing future vSEMERA editions, our results may offer insights for similar projects that address the targeted integration of scientific research education into an international, digital learning environment.

How an international research programme can contribute to improvements in the research environment: the perspective of doctoral students in sub-Saharan Africa.

The Africa Capacity Building Initiative (ACBI) programme aimed to 'strengthen the research and training capacity of higher education institutions and support the development of individual scientists in sub-Saharan Africa through UK-Africa research collaborations' including by funding PhD studentships. We conducted research to understand students' experiences and to see how consortia-based programmes such as ACBI and their own institutions can enhance PhD students' research environment and progress. In-depth interviews with 35 ACBI-funded PhD students explored their perspectives about how their research and personal development benefitted from belonging to a research consortium. Questionnaires were used to corroborate interview findings. Students recognised that membership of a research consortium provided many benefits compared to less well-resourced peers. By drawing on the programme and consortiums' resources, they were often able to overcome some limitations in their own institution's systems and facilities. Through their consortia they could access a wide range of international expertise and support from mentors and colleagues for their technical and psychosocial needs. Multiple consortia opportunities for engaging with the international scientific community and for networking, gave them confidence and motivation and enhanced their career prospects. Our study and its recommendations highlight how the breadth and diversity of resources available to PhD students through research consortia can be harnessed to facilitate students' progress and to create a supportive and conducive research environment. It also underlines how, through a multi-level approach, consortia can contribute to longer-term improvements in institutional research environments for PhD students.

Cultural adaptation of INDIGO mental health stigma reduction interventions using an ecological validity model in north India.

The International Study of Discrimination and Stigma Outcomes (INDIGO) Partnership is a multi-country international research program in seven sites across five low- and middle-income countries (LMICs) in Africa and Asia to develop, contextually adapt mental health stigma reduction interventions and pilot these among a variety of target populations. The aim of this paper is to report on the process of culturally adapting these interventions in India using an established framework. As part of this larger program, we have contextualized and implemented these interventions from March 2022 to August 2023 in a site in north India. The Ecological Validity Model (EVM) was used to guide the adaptation and contextualization process comprising eight dimensions. Six dimensions of the Ecological Validity Model were adapted, namely language, persons, metaphors, content, methods, and context; and two dimensions, namely concepts and goals, were retained. Stigma reduction strategies with varied target groups, based on culturally appropriate adaptations, are more likely to be acceptable to the stakeholders involved in the intervention, and to be effective in terms of the program impact.

The development and evaluation of a short-term international student research and educational program

ObjectivesThis study aimed to describe the “how-to” details and processes for developing and evaluating a short-term international student research and education program. MethodsThis study included two parts: development and implementation, and evaluation of the program. A foreign doctoral nursing student requested to visit the West Virginia University School of Nursing for research training and academic teaching experience. The global nursing program coordinator and the lead mentor met and identified the program basis and team participants. Learning activities were related to this student’s interest in older adults and in-home end-of-life care, included four contents: research; educational engagement; practice/clinical engagement; special activities & professional development training and courses. The program evaluation was conducted at the end of the six-month visit using a focus group and an anonymous short survey. Participants (n = 10) included the host university’s faculty, graduate students, and one short-term international student. ResultsContent analysis of the participant’s short survey answers and the focus group discussion resulted in three themes: 1) lessons learned from participating in the program (enhanced diversity in education and research, gaining new global healthcare knowledge, and self-reflection on and promoting cultural awareness); 2) program barriers and challenges (the visa application process, the English language barrier, the lack of public transportation in the town, and scheduling conflicts); and 3) strategies to overcome these barriers and challenges (adding cultural diversity information into curriculum; attending English proficiency with others in the class; using different communication techniques; continuous collaboration with the University’s Office of Global Affairs for the Visa application process; providing interactive experiences). All participants rated their engagement in the program as very satisfactory (Mean = 4.67, SD = 0.50), and highly impacted their nursing skills in research, teaching, and clinical practice (Mean = 4.67, SD = 0.50). ConclusionsAll the participants have gained some experience in this program, which can be used for future teaching guidance. Further, international nursing students need assistance to adjust and thrive in the host university learning community. Faculty must be culturally sensitive, understand the visiting foreign nursing student’ learning needs, and advocate for an environment suitable for enhancing the students’ learning.

Experimental investigation of uranium release from spent nuclear fuels under conditions expected in a deep geological repository

Abstract. Direct disposal of spent nuclear fuel (SNF) in a deep geological repository is planned for the long-term management of the highly radioactive waste discharged from the light water reactors (LWRs) of nuclear power plants in Germany. The aim is to safely isolate the radionuclide inventory from the biosphere, ad infinitum, making use of a multi-barrier system consisting of technical, geotechnical and geological barriers interposed between the emplaced waste and the environment. Still, reversibility measures including retrievability of the waste products are considered in this concept. Internationally, in safety assessments for deep underground repositories (DGRs), the access of groundwater, followed by failure of canisters and finally loss of the SNF's cladding integrity is considered in the long term. Hence, the evaluation of the performance of SNF in the near field of a deep geological repository requires process understanding of SNF dissolution and rates, in addition to the quantification of the radionuclide release from SNF under reducing conditions of a breached container. With the aim to derive a radionuclide source term, the SNF dissolution and alteration processes can be assigned to two steps, namely the (i) instantaneous release of radionuclides upon cladding failure from gap and grain boundaries and (ii) a long-term release that results from the dissolution of the fuel grains themselves (Ewing, 2015). Since most radionuclides produced during irradiation of nuclear fuel in a reactor are trapped within the SNF matrix, understanding the processes leading to the dissolution of the matrix and its dissolution rates are of particular interest for post-closure safety assessments (Pastina and LaVerne, 2021). Research at the Institute for Nuclear Waste Disposal (INE) at the Karlsruhe Institute of Technology (KIT) has focused, for more than 25 years, on the behaviour of SNF (irradiated UO2 and mixed-oxide, MOX, fuels) under geochemical conditions (pH, redox milieu, gas atmosphere and ionic strength) representative of various repository concepts and radiolytic reactions on SNF dissolution mechanisms. This contribution will give an overview on the radionuclide release from dissolving SNFs under repository conditions. In particular, uranium released into solution from UO2 and MOX fuels during up to 1629 d of leaching in salt brines, granitic/bentonitic or cementitious groundwaters under Ar or Ar/H2 atmospheres. As observed in other published studies on SNF dissolution under reducing conditions, a large scatter of the uranium concentration is seen in the initial stages of our experiments. After about 1 year of leaching, the aqueous concentration of uranium slowly approaches the solubility limit of U(IV), independent of the type of studied SNF samples (various irradiated UO2 and MOX fuels). A similar behaviour is observed for other redox-sensitive actinides. The release rate of uranium decreases significantly in all experiments within first 400 d of leaching. Although the rate is very low, it is >0, and a continuous release is observed. A comparison of the results from SNF experiments under various redox conditions demonstrates that oxidative matrix dissolution is inhibited due to the presence of hydrogen. Our results are discussed in the context of the outcome of international research programmes on SNF corrosion. These findings are considered to be of relevance for the definition of source terms for various irradiated LWR fuels in safety investigations for a DGR in Germany.

Giving a Voice to Nurse Managers and Staff Nurses: A Two-Centres Multi-Method Research Protocol to Optimize Nurses’ Actual Scope of Practice

Introduction: Numerous studies have revealed that a limited time is devoted to value-added care activities that are part of nurses’ professional role (Déry et al., 2022). This has an impact on the performance of healthcare systems in terms of overall costs. The COVID-19 pandemic has put more pressure on healthcare organizations, on its nurse managers (NMs) and staff nurses. Objective: To mobilize key players in care units to propose effective and realistic strategies to facilitate the optimal deployment of nursing practice. Methods: This international research program encompasses 3 consecutive cross-sectional studies involving 2 healthcare centres: 1 in Canada and 1 in Switzerland. Study 1’s qualitative design will include focus groups with NMs. Study 2’s quantitative correlational design will survey staff nurses. Study 3 will include multiple meetings with NMs, staff nurses, clinical nurse specialists and educators (key players) to develop a logic model of intervention to propose effective and realistic strategies to facilitate the full deployment of nurses’ scope of practice. Discussion and Research Spin-offs: Study 1 will help describe the innovative management practices of NMs since the onset of the COVID-19 pandemic and identify their support and educational needs. Study 2 will explore the perceptions of staff nurses regarding the work psychological climate and work recognition, their actual scope of practice, their professional satisfaction at work and their perception of the quality of care. Study 3 will take advantage of this new data and mobilize key players in the identification of improvement strategies adapted to their own reality.

The renaissance of ordoliberalism in the 1970s and 1980s*

AbstractThe economic tradition of ordoliberalism, understood as the theoretical and policy ideas of the Freiburg School, emerged in 1930s and 1940s Germany. In the years thereafter, it was quickly superseded by Keynesianism and other theories imported from the English-speaking world. The crisis in Keynesian economics in the mid-1970s led to what has been described as a “renaissance of ordoliberal reasoning” (Gebhard Kirchgässner) during the late 1970s and the 1980s. The present paper describes this development in detail and shows how it affected the academic discourse and, more indirectly, policymaking. In academic economics, ordoliberal concepts were used to inform debates about pressing issues of the day such as unemployment, social security reform, competition policy, the provision of public goods, and European integration. There was, however, no consensus on the methodological question of whether ordoliberalism could be fully integrated into international research programs such as the new institutional economics or constitutional economics. The paper argues that the renaissance of ordoliberalism failed to have a lasting impact on German academic economics and discusses possible implications of this finding for the future of the ordoliberal research agenda.

The challenges of international collaboration in conflict and health research: experience from the Research for Health in Conflict-Middle East and North Africa (R4HC-MENA) partnership

BackgroundHealthcare is a basic human right extending across all humanitarian contexts, including conflict. Globally, two billion people are living under conditions of insecurity and violent armed conflict with a consequent impact on public health. Health research in conflict-affected regions has been recognised as important to gain more understanding of the actual needs of such populations, to optimise healthcare delivery, as well as to inform advocacy and policy change. International collaborative research maximises the resources and skills available for dealing with global health issues, builds capacity and endeavours to ensure the research reflects real needs of the populations. Under the UK’s Global Challenge Research Fund in 2017 a number of such international programs were created including the Research for Health in Conflict-Middle East and North Africa (R4HC-MENA) partnership to build capacity in conflict and health research as well as study specific areas, namely noncommunicable diseases in conflict (cancer & mental health) and the political economy of health in conflict.MethodsA qualitative study using semi-structured online interviews was conducted to explore researchers’ and stakeholders’ perspectives on the R4HC-MENA programme over its lifetime from 2017 to 2021. It aimed to understand the factors that influenced and accelerated international collaboration within the R4HC-MENA programme on conflict and health research, and to provide deeper insights into the implementation of the programme. Data collection was conducted from March 2022 to June 2022. Purposive and snowball sampling techniques were used for participant recruitment. Thematic analysis was applied for data analysis.ResultsTwelve researchers/stakeholders participated in this study: four men and eight women. Four main themes were generated: Theme 1: Network building (personal and institutional levels); Theme 2: Hierarchies and power dynamics (power imbalance between different academic status, genders and institutions); Theme 3: Communication challenges; Theme 4: Career development (management, leadership, research, and teaching skills).ConclusionsThis study provided preliminary insights into perspectives on international collaboration in a major international programme of research on conflict and health. Several key challenges and outputs were generated by the researchers in this study. The findings are important for further developing effective strategies to tackle the challenge of power imbalance and ineffective communication in international research collaborations.

Cannabis use and psychotic disorders in diverse settings in the Global South: findings from INTREPID II.

Cannabis use has been linked to psychotic disorders but this association has been primarily observed in the Global North. This study investigates patterns of cannabis use and associations with psychoses in three Global South (regions within Latin America, Asia, Africa and Oceania) settings. Case-control study within the International Programme of Research on Psychotic Disorders (INTREPID) II conducted between May 2018 and September 2020. In each setting, we recruited over 200 individuals with an untreated psychosis and individually-matched controls (Kancheepuram India; Ibadan, Nigeria; northern Trinidad). Controls, with no past or current psychotic disorder, were individually-matched to cases by 5-year age group, sex and neighbourhood. Presence of psychotic disorder assessed using the Schedules for Clinical Assessment in Neuropsychiatry and cannabis exposure measured by the World Health Organisation Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). Cases reported higher lifetime and frequent cannabis use than controls in each setting. In Trinidad, cannabis use was associated with increased odds of psychotic disorder: lifetime cannabis use (adj. OR 1.58, 95% CI 0.99-2.53); frequent cannabis use (adj. OR 1.99, 95% CI 1.10-3.60); cannabis dependency (as measured by high ASSIST score) (adj. OR 4.70, 95% CI 1.77-12.47), early age of first use (adj. OR 1.83, 95% CI 1.03-3.27). Cannabis use in the other two settings was too rare to examine associations. In line with previous studies, we found associations between cannabis use and the occurrence and age of onset of psychoses in Trinidad. These findings have implications for strategies for prevention of psychosis.

A review of beaked whale behaviour and ecology in relation to assessing and mitigating impacts of anthropogenic noise

Little is known about the ecology and behaviour of species within the family Ziphiidae. In this paper, five aspects of beaked whale ecology and behaviour are reviewed in relation to possible anthropogenic impacts upon them: social structure; life history; foraging/diving ecology; form and function of beaked whale sounds; and habitat characteristics. Differences in social structure within and between species may affect how anthropogenic activities affect local populations. Life history parameters may likewise vary within and between species and may influence the extent of and ability to recovery from population level impacts. Foraging and diving ecology determine where beaked whales spend most of their time and therefore, where in the water column they are most likely to encounter anthropogenic activities. The form and function of beaked whale sounds may be important in determining whether and how beaked whales are affected by anthropogenic noise. Finally, habitat characteristics determine whether beaked whales are likely to occur in a specific area where anthropogenic activities are to be undertaken and may also determine exactly how beaked whales are affected by it within a local area. To help fill the gaps in our knowledge of beaked whale behaviour and ecology, available opportunities for data collection must be maximised. This includes greater levels of co-operation between research groups to build up large datasets, the use of platforms of opportunity to study beaked whales in areas where little research has previously been undertaken and maximising the amount of information that can be learned from each possible source of data, such as stranded animals, through co-ordinated national and international research programmes.

From sequences to species: Charting the phytoplasma classification and taxonomy in the era of taxogenomics.

Phytoplasma taxonomy has been a topic of discussion for the last two and half decades. Since the Japanese scientists discovered the phytoplasma bodies in 1967, the phytoplasma taxonomy was limited to disease symptomology for a long time. The advances in DNA-based markers and sequencing improved phytoplasma classification. In 2004, the International Research Programme on Comparative Mycoplasmology (IRPCM)- Phytoplasma/Spiroplasma Working Team - Phytoplasma taxonomy group provided the description of the provisional genus 'Candidatus Phytoplasma' with guidelines to describe the new provisional phytoplasma species. The unintentional consequences of these guidelines led to the description of many phytoplasma species where species characterization was restricted to a partial sequence of the 16S rRNA gene alone. Additionally, the lack of a complete set of housekeeping gene sequences or genome sequences, as well as the heterogeneity among closely related phytoplasmas limited the development of a comprehensive Multi-Locus Sequence Typing (MLST) system. To address these issues, researchers tried deducing the definition of phytoplasma species using phytoplasmas genome sequences and the average nucleotide identity (ANI). In another attempts, a new phytoplasma species were described based on the Overall Genome relatedness Values (OGRI) values fetched from the genome sequences. These studies align with the attempts to standardize the classification and nomenclature of 'Candidatus' bacteria. With a brief historical account of phytoplasma taxonomy and recent developments, this review highlights the current issues and provides recommendations for a comprehensive system for phytoplasma taxonomy until phytoplasma retains 'Candidatus' status.

Benchmarking of Irrigation Performance in Karataş and Karaçal Irrigation Associations

This study was carried out to evaluate the system performances of Karataş and Karaçal irrigation associations located in Burdur province. Karataş irrigation association was put into operation in 1982 and Karaçal irrigation association in 2015 with irrigation areas are 5476 and 4975 ha, respectively. The same public personnel were appointed to both irrigation associations as the Head of the Association in 2018, and as of 2019, both irrigation Associations were gathered under the management of Karataş irrigation association. In this study, the performances of Karataş irrigation, which has an old and predominantly open canal system, and Karaçal irrigation systems, which are relatively new and have a pressurized irrigation system, between the years 2015-2019 have been evaluated. In the performance evaluation, a set of indicators under two main headings as water use efficiency, and financial efficiency recommended by the International Technology and Research Program in Irrigation and Drainage (IPTRID) was used. According to the results of the research, when the water use efficiency is examined, especially Annual relative irrigation supply (0.53-0.73 for Karataş; 0.47-0.96 for Karaçal) and irrigation ratio (20-72% for Karataş; 36% for Karaçal) 55) values were not at the desired levels. In terms of Financial Efficiency, cost recovery ratio (119-401% for Karataş; 144-311 for Karaçal) and revenue collection performance (78-442% for Karataş; 10-130 for Karaçal) were found to be high. Although this is a new irrigation, Karaçal irrigation shows that relatively high maintenance costs are incurred. Total operating maintenance and management (MOM) cost per unit area is US$ 9.60-14.98/ha for Karataş and as 1.32-22.92 US$/ha for Karaçal. These values showed that, in general, both irrigations have sufficient financial strength.

THE CONTENT OF THE PRIMARY SCIENCE EDUCATION IN THE CONTEXT OF TIMSS INTERNATIONAL STUDY PROGRAM REQUIREMENTS

The article deals with the peculiarities of TIMSS international research program natural science component. The relevance of the primary science education research by means of TIMSS has been substantiated: the international research covers more than 50 world countries; it defines an opportunity for teachers and scientists to assess the state of primary students’ scientific literacy in comparison with other countries; the factors influencing the quality of natural science education have been found out; ways to improve the content of the natural science training in the primary school have been defined.
 The purpose of the article is to compare the content of the natural science by primary typical curriculum and the TIMSS international program, to suggest the ways to improve the natural science education of primary school students in domestic school. The Research methods – comparative analysis, generalization of results. A comparative analysis of the natural education content within a typical primary curriculum and the international TIMSS program for the 4th grade students has been carried out. The content blocks of the basic natural-scientific branches to estimate primary pupils’ natural-scientific literacy have been discussed. Themes of natural character absent in the elementary school typical curriculum have been defined. The goals of studying natural topics according to the international program and the expected results of the natural education field have been compared. The main tasks for cognitive areas (“knowledge”, “applying”, “reasoning”) assessment have been stated. Sample tasks for the fourth-graders’ natural literacy assessing have been given. The content of the concepts “natural sciences competency”, “natural sciences educational achievements”, “natural science literacy” has been revealed. Ways to improve primary school natural training in Ukraine have been suggested.

History of the development of domestic psychiatry: the period 1940-1980

The article briefly presents an analysis of the development of domestic psychiatry (with an emphasis on research in the field of psychopathology and nosology) from the post-war period (the Great Patriotic War) to the era of "perestroika". With the founding of the Institute of Psychiatry of the USSR Academy of Medical Sciences under the leadership of V.A. Gilyarovsky, the study of endogenous diseases was based on a multidisciplinary approach, in which the clinical-psychopathological research method was combined with clinical/biological ones. The most important role of the subsequent school of A.V. Snezhnevsky in describing the syndromes and forms of the course of schizophrenia (G.A. Rotshtein, R.A. Nadzharov, A.B. Smulevich, A.K. Anufriev), its age aspects (E.Ya. Sternberg; M.S. Vrono, G.P. Panteleeva, M.Ya. Tsutsulkovskaya; V.M. Bashina) is reflected. The contribution to psychopathology of other leading Russian psychiatrists, who worked mainly in Moscow and Leningrad research institutions of that period, was noted: students of P.B. Gannushkin - O.V. Kerbikov, V.M. Morozov, D.S. Ozeretskovsky, S.G. Zhislin, as well as G.K. Ushakov, A.E. Lichko, M.M. Kabanov, G.V. Morozov, M.V. Korkina, A.A. Portnov, I.N. Pyatnitskaya and others. The priority of A.V. Snezhnevsky and G.K. Avrutsky with colleagues for the introduction of neuroleptics and other new psychotropic drugs in the treatment of mental illnesses is emphasized. The review ends with the activities of M.E. Vartanyan who headed the country's leading scientific institution in the difficult «perestroika» era and developed the biological approach to mental illness further with the creation of international research programs.

Epidemiology of Untreated Psychoses in 3 Diverse Settings in the Global South

Less than 10% of research on psychotic disorders has been conducted in settings in the Global South, which refers broadly to the regions of Latin America, Asia, Africa, and Oceania. There is a lack of basic epidemiological data on the distribution of and risks for psychoses that can inform the development of services in many parts of the world. To compare demographic and clinical profiles of cohorts of cases and rates of untreated psychoses (proxy for incidence) across and within 3 economically and socially diverse settings in the Global South. Two hypotheses were tested: (1) demographic and clinical profiles of cases with an untreated psychotic disorder vary across setting and (2) rates of untreated psychotic disorders vary across and within setting by clinical and demographic group. The International Research Program on Psychotic Disorders in Diverse Settings (INTREPID II) comprises incidence, case-control, and cohort studies of untreated psychoses in catchment areas in 3 countries in the Global South: Kancheepuram District, India; Ibadan, Nigeria; and northern Trinidad. Participants were individuals with an untreated psychotic disorder. This incidence study was conducted from May 1, 2018, to July 31, 2020. In each setting, comprehensive systems were implemented to identify and assess all individuals with an untreated psychosis during a 2-year period. Data were analyzed from January 1 to May 1, 2022. The presence of an untreated psychotic disorder, assessed using the Schedules for Clinical Assessment in Neuropsychiatry, which incorporate the Present State Examination. Identified were a total of 1038 cases, including 64 through leakage studies (Kancheepuram: 268; median [IQR] age, 42 [33-50] years; 154 women [57.5%]; 114 men [42.5%]; Ibadan: 196; median [IQR] age, 34 [26-41] years; 93 women [47.4%]; 103 men [52.6%]; Trinidad: 574; median [IQR] age, 30 [23-40] years; 235 women [40.9%]; 339 men [59.1%]). Marked variations were found across and within settings in the sex, age, and clinical profiles of cases (eg, lower percentage of men, older age at onset, longer duration of psychosis, and lower percentage of affective psychosis in Kancheepuram compared with Ibadan and Trinidad) and in rates of untreated psychosis. Age- and sex-standardized rates of untreated psychoses were approximately 3 times higher in Trinidad (59.1/100 000 person-years; 95% CI, 54.2-64.0) compared with Kancheepuram (20.7/100 000 person-years; 95% CI, 18.2-23.2) and Ibadan (14.4/100 000 person-years; 95% CI, 12.3-16.5). In Trinidad, rates were approximately 2 times higher in the African Trinidadian population (85.4/100 000 person-years; 95% CI, 76.0-94.9) compared with the Indian Trinidadian (43.9/100 000 person-years; 95% CI, 35.7-52.2) and mixed populations (50.7/100 000 person-years; 95% CI, 42.0-59.5). This analysis adds to research that suggests that core aspects of psychosis vary by historic, economic, and social context, with far-reaching implications for understanding and treatment of psychoses globally.

Ec-Funded Projects’ Lessons Learned In Earth Friendly Freight Transportation

Abstract The paper is based on the research project ePIcenter (www.ePIcenterproject.eu) supported by the EU HORIZON 2020 Programme. ePIcenter connects thirty-six partners: port authorities, logistic service providers, manufacturers, academic institutions, and technology partners. The main goal is to develop and test AI driven logistic software solutions, apply new technologies and methodologies to increase the efficiency of global supply chains and reduce their environmental impact. One of the significant aspect the project focusses on is optimisation, using AI, digitalisation, automation and innovations in freight transport and handling technologies. Finally, modelling powerful solutions to enable resilient, efficient and environment friendly supply chains. Knowledge sharing is one of powerful tool for researchers, policymakers, service providers and other stakeholders to develop a holistic and comprehensive common knowledge base. First, a theoretical framework had been developed through identification and review knowledge available from previous projects funded through the European Commission as well as other international funding projects. Second, lessons learned and success stories from previous EC-funded projects and other international research programmes were reviewed and provided in the first year of project implementation.

Estella Atekwana: Autobiographical Notes

I describe my career journey from a young girl in Cameroon, West Africa, to a trailblazing geophysicist to my current role as dean. I chronicle my time as a student, the transition to being an early career faculty, launching my research career, and ultimately finding my way to administration. Along the way I helped pioneer biogeophysics as a subdiscipline in geophysics while simultaneously maintaining an international research program in continental rift tectonics. I also describe the many intersectionalities in my life including being the first Black woman in many spaces, being a champion for student success, developing a diverse talent pipeline by enhancing diversity in the geosciences, and navigating academic job searches as part of a dual-career couple. Finally, I acknowledge all those who helped shape my career including the many students I had the opportunity to mentor. ▪ Many underrepresented minority geoscientists lack the social capital and professional networks critical for their success. ▪ Geoscience departments must be intentional and deliberate in promoting and ensuring more inclusive workplace environments. ▪ Dual-career couples remain a major challenge, impacting retention and recruitment of top talent; universities should provide resources to alleviate this challenge. ▪ Biogeophysics has untapped potential for advancing understanding of subsurface biogeochemical processes and the search for life in extreme environments. ▪ To date, considerable speculation remains regarding the fundamental geodynamic processes that initiate and sustain the evolution of magma-deficient rifts.