Education has a central role towards humanity development. While it aims to build the capacity of people to be socialized and valued persons, it also develops societies to take advantage in the society of knowledge in the 21st Century. For this reason, the significant purposes of the international educational programs aim at effective learning strategies and curricula covering the contemporary needed issues like modern culture, advanced technology, civil society, and peace building. (Fourth International Conference of e-Learning and Distance Education, KSA, 2015; 2nd International Conference on Education, Culture and Identity. Europe, Bosnia; 2015; 2nd International Conference on Education, Beijing, China, 2015; and the International Conference on Education and e-learning, Cairo, Egypt, 2015, United Nations, 2003). Therefore, those issues would be putting on the highest among the educational objectives for getting new learning outcomes, along with considering the educational institutes that the main responsible bodies for providing learners with the culture and experiences necessary for better life for the third millennium. Najran University located in Najran city in Saudi Arabia. Both of university and city have the same targets toward solving the domestic problems, and keeping pace with the international challenges. The university works to develop a scientific base agreeing with the original culture of students and people. So it needs to adopt an educational approach would be able to collect between modern culture and society traditions at the same learning environment, considering science, technology, society, and religious concepts. In this regard, Science, Technology, and Society (STS) approach is a learning treatment, it would be the suggested learning method to help students in attaining integrative knowledge and the society culture needed. The characteristics of that approach allow to study by collecting STS Fields in the same environment simultaneously (Nuray Yoruk, Inci Morgil, and Nilgun Secken, 2010, 1417-1424; Nasser Mansour, 2009, 287-297). This study involves teaching a course of curriculum foundations by using the Science, Technology, Society and Religion (STSR) approach for students at Najran University, and examination of its possible effectiveness on students' achievement and development of their inclinations towards study.