Introduction: holistic patient care, which integrates the efforts of Internal Medicine, Anesthesiology, and Surgical Practices, has been shown to improve patient outcomes across the continuum of care. This review aimed to explore the synergy between these specialties and highlight how their collaboration contributes to comprehensive, patient-centered care.Method: a narrative review was conducted using peer-reviewed literature from databases such as PubMed, Scopus, and Google Scholar. The search focused on articles published in the last 15 years, using terms related to interdisciplinary collaboration in healthcare. Data from relevant studies were synthesized and grouped into preoperative, intraoperative, and postoperative phases, with emphasis on how each specialty contributes to holistic care.Results: the review demonstrated that collaboration between these specialties is essential for optimizing preoperative risk management, ensuring intraoperative stability, and enhancing postoperative recovery. Internal Medicine played a key role in managing chronic conditions preoperatively, while Anesthesiology tailored anesthesia plans and managed perioperative pain. Surgical Practices, guided by insights from the other specialties, executed patient-centered surgeries. Despite the benefits, challenges such as communication barriers and resource limitations were identified.Conclusion: this review highlighted the critical role of interdisciplinary collaboration in holistic patient care. While the synergy between Internal Medicine, Anesthesiology, and Surgical Practices improved patient outcomes, addressing communication challenges and resource constraints is essential for further enhancing care quality.